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New Therapeutic Modalities in Liver Inflammation and Fibrosis
Authors
1Associate Professor, Department of Intensive Care Unit and Anesthesiology
2Clinical Fellow
3Professor of Pharmacotherapy, Sina Hospital, Tehran Uni-versity of Medical Sciences. Iran
*Corresponding Author: Department of Intensive Care Unit, Sina Hospital, Tehran, Iran, falahianfff@yahoo.com. Tel: +98-2188003264. Fax: +98-2188945188. Email: falahianfff@yahoo.com
Published online:Apr 02, 2011
Article type:Review Article
Received:Jul 21, 2010
Accepted:Jan 01, 2011
How to Cite:Najafi A, Fallahian F, Khajavi M, Mojtahedzadeh M. New Therapeutic Modalities in Liver Inflammation and Fibrosis. Shiraz E-Med J. 2011;12(2):20483. doi:
Abstract
Understanding the molecular and cellular mechanisms underlying liver inflammation and fibrosis would facilitate to design appropriate therapeutic interventions to halt or reverse the process of liver fibrosis. A review of literature was performed in 2010 to summarize scientific reports on inflammation pathways of hepatitis. Articles indexed in the Pub Med database during recent ten years searched for hepatitis, inflammation pathways, treatment modalities, and stem cell transplantation to investigate cellular and molecular pathways and biologic role of growth factors, cytokines, and mediators engaged in liver inflammation facilitate the de-velopment of pharmacological intervention. This manuscript reviews some recent scientific advances, and therapeutic interventions in liver inflammation, and fibrosis
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Copyright
© 2011, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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