1. Background
2. Objectives
3. Methods
3.1. Study the Population
3.2. Study Protocol
3.3. Statistical Analysis
4. Results
4.1. Baseline Characteristics
| Variables | Total (N = 358) | GHQ < 24 (N = 137, 38.3%) | GHQ ≥ 24 (N = 221, 61.7%) | P-Value |
|---|---|---|---|---|
| Age | 25.43 ± 2.31 | 25.37 ± 2.33 | 25.46 ± 2.31 | 0.724 |
| Gender | 0.026 | |||
| Male | 177 (49.4) | 78 (56.9) | 99 (44.8) | |
| Female | 181 (50.5) | 59 (43.1) | 122 (55.2) | |
| Internship months | 0.087 | |||
| ≤ 6 | 71 (19.8) | 20 (14.6) | 51 (23.1) | |
| 6 - 12 | 60 (16.7) | 21 (15.3) | 39 (17.6) | |
| 12 - 24 | 227 (63.4) | 96 (70.1) | 131 (59.3) | |
| Hometown | 0.328 | |||
| Tehran | 179 (50) | 64 (46.7) | 115 (52) | |
| Others | 179 (50) | 73 (53.3) | 106 (48) | |
| Economic status | 0.133 | |||
| Poor/middle | 206 (57.5) | 72 (52.6) | 134 (60.6) | |
| Good | 152 (42.5) | 65 (47.4) | 87 (39.4) | |
| Marital status | 0.975 | |||
| Single | 295 (82.4) | 113 (82.5) | 182 (82.4) | |
| Married | 63 (24.4) | 24 (17.5) | 39 (17.6) | |
| Current department | 0.167 | |||
| Emergency/Surgery | 62 (17.3) | 23 (16.8) | 39 (17.6) | |
| Internal medicine b | 139 (38.8) | 55 (40.1) | 84 (38) | |
| Pediatric | 23 (6.42) | 5 (3.6) | 18 (8.1) | |
| Gynecology | 22 (6.14) | 5 (3.6) | 17 (7.7) | |
| Others | 112 (31.3) | 49 (35.8) | 63 (28.5) | |
| Accommodation | 0.528 | |||
| Dormitory | 64 (17.9) | 29 (21.2) | 35 (15.8) | |
| Home with family | 217 (60.6) | 82 (59.9) | 135 (61.1) | |
| Home with friends | 14 (3.9) | 4 (2.9) | 10 (4.5) | |
| Home alone | 63 (17.6) | 22 (16.1) | 41 (18.6) | |
| Interest in medicine | 0.015 | |||
| Low | 30 (8.4) | 9 (6.6) | 21 (9.5) | |
| Medium | 164 (45.8) | 52 (38.0) | 112 (50.7) | |
| High | 164 (45.8) | 76 (55.5) | 88 (39.8) | |
| Hope for career prospects | < 0.001 | |||
| Low | 94 (26.3) | 16 (11.7) | 78 (35.3) | |
| Medium | 203 (56.7) | 83 (60.6) | 120 (54.3) | |
| High | 61 (17.0) | 38 (27.7) | 23 (10.4) | |
| Personal life satisfaction | < 0.001 | |||
| Low | 67 (18.7) | 7 (5.1) | 60 (27.1) | |
| Medium | 196 (54.7) | 69 (50.4) | 127 (57.5) | |
| High | 95 (26.5) | 61 (44.5) | 34 (15.4) | |
| Physical/mental disease | 0.042 | |||
| Yes | 66 (18.4) | 18 (13.1) | 48 (21.7) | |
| No | 292 (81.6) | 119 (86.9) | 173 (78.3) |
Abbreviation: GHQ, General Health Questionnaire.
a Values are expressed as No. (%) or mean ± SD.
bInternal medicine, cardiology, infectious diseases, and toxicology.
4.2. Factors Associated with GHQ Score Equal or Greater Than 24
| Variables | Mean ± SD | Unadjusted Model | Adjusted Model | ||
|---|---|---|---|---|---|
| OR (95% CI) | P-Value | OR (95%CI) | P-Value | ||
| Age | - | 1.02 (0.93 - 1.12) | 0.723 | NA a | NA |
| Gender | |||||
| Female | 33.01 ± 14.58 | 1.64 (1.06 - 2.50) | 0.026 | 1.78 (1.12 - 2.85) | 0.015 |
| Male | 27.10 ± 13.72 | Reference | Reference | ||
| Internship months | |||||
| ≤ 6 | 31.24 ± 14.19 | 1.87 (1.05 - 3.34) | 0.035 | NA | NA |
| 6 - 12 | 34.33 ± 15.75 | 1.36 (0.75 - 2.46) | 0.308 | NA | NA |
| 12 - 24 | 28.60 ± 13.97 | Reference | NA | NA | |
| Home town | |||||
| Tehran | 31.15 ± 14.85 | 1.24 (0.80 - 1.89) | 0.328 | NA | NA |
| Others | 29.03 ± 13.99 | Reference | NA | NA | |
| Economic status | |||||
| Poor/middle | 31.11 ± 14.55 | 1.39 (0.90 - 2.14) | 0.133 | NA | NA |
| Good | 28.70 ± 14.24 | Reference | NA | NA | |
| Marital status | |||||
| Single | 30.17 ± 14.42 | 0.99 (0.56 - 1.73) | 0.975 | NA | NA |
| Married | 29.70 ± 14.67 | Reference | NA | NA | |
| Current department | |||||
| Emergency/surgery | 33.26 ± 15.88 | 1.32 (0.70 - 2.49) | 0.394 | NA | NA |
| Internal medicine b | 29.72 ± 14.26 | 1.19 (0.72 - 1.97) | 0.504 | NA | NA |
| Pediatric | 32.30 ± 14.55 | 2.80 (0.97 - 8.07) | 0.057 | NA | NA |
| Gynecology | 35.27 ± 13.62 | 2.64 (0.91 - 7.67) | 0.073 | NA | NA |
| Others | 27.31 ± 13.53 | Reference | NA | NA | |
| Accommodation | |||||
| Dormitory | 26.42 ± 12.05 | 0.65 (0.32 - 1.32) | 0.648 | NA | NA |
| Home with family | 30.61 ± 15.04 | 0.88 (0.49 - 1.59) | 0.883 | NA | NA |
| Home with friends | 28.93 ± 11.63 | 1.34 (0.38 - 4.778) | 0.377 | NA | NA |
| Home alone | 32.27 ± 14.77 | Reference | NA | NA | |
| Interest in medicine | |||||
| Low | 31.67 ± 13.76 | 2.02 (0.87 - 4.66) | 0.102 | NA | NA |
| Medium | 33.24 ± 14.893 | 1.86 (1.18 - 2.92) | 0.007 | NA | NA |
| High | 26.65 ± 13.389 | Reference | NA | NA | |
| Hope for career prospects | |||||
| Low | 37.98 ± 15.87 | 8.05 (3.82 - 16.99) | < 0.001 | 4.09 (1.80 - 9.23) | 0.001 |
| Medium | 28.63 ± 12.96 | 2.39 (1.33 - 4.30) | 0.004 | 1.61 (0.85 - 3.07) | 0.147 |
| High | 22.77 ± 11.27 | Reference | Reference | ||
| Personal life satisfaction | |||||
| Low | 42.13 ± 13.92 | 15.38 (6.33 - 37.38) | < 0.001 | 10.94 (4.33 - 27.66) | < 0.001 |
| Medium | 30.18 ± 13.38 | 3.30 (1.98 - 5.50) | < 0.001 | 2.55 (1.47 - 4.42) | 0.001 |
| High | 21.40 ± 10.29 | Reference | Reference | ||
| Physical/mental disease | |||||
| Yes | 36.73 ± 16.27 | 1.83 (1.02 - 3.31) | 0.044 | NA | NA |
| No | 28.59 ± 13.59 | Reference | NA | NA | |
a Not applicable (NA) indicates that the variable was not included in the multivariable regression equation.
bInternal medicine, cardiology, infectious diseases, and toxicology.
4.3. Factors Associated with Subscale Scores
| Variables | Subscale A (Somatic Symptoms) | Subscale B (Anxiety and Insomnia) | Subscale C (Social Dysfunction) | Subscale D (Severe Depression) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Descriptivea | Adjusted Modelb | P-Value | Descriptivea | Adjusted Modelb | P-Value | Descriptivea | Adjusted Modelb | P-Value | Descriptivea | Adjusted Modelb | P-Value | |
| Total | 7.23 ± 4.22 | - | - | 8.93 ± 5.03 | - | - | 8.87 ± 3.59 | - | - | 5.06 ± 4.69 | - | - |
| Gender | ||||||||||||
| Female | 8.43 ± 3.98 | 2.41 ± 0.41 | < 0.001 | 9.94 ± 4.98 | 2.02 ± 0.49 | < 0.001 | 9.08 ± 3.80 | NA c | NA | 5.55 ± 5.01 | 1.10 ± 0.43 | 0.010 |
| Male | 6.00 ± 4.11 | Reference | 7.89 ± 4.88 | Reference | 8.66 ± 3.37 | NA | NA | 4.55 ± 4.30 | Reference | - | ||
| Internship months | ||||||||||||
| ≤ 6 | 7.44 ± 4.02 | NA | NA | 9.93 ± 5.38 | NA | NA | 8.72 ± 3.57 | NA | NA | 5.15 ± 4.82 | NA | NA |
| 6 - 12 | 8.63 ± 4.84 | 1.84 ± 0.55 | 0.001 | 10.00 ± 5.28 | NA | NA | 9.97 ± 3.68 | NA | NA | 5.73 ± 4.75 | NA | NA |
| 12 - 24 | 6.79 ± 4.04 | Reference | - | 8.33 ± 4.77 | NA | NA | 8.63 ± 3.54 | NA | NA | 4.85 ± 4.64 | NA | NA |
| Hometown | ||||||||||||
| Tehran | 7.63 ± 4.41 | NA | NA | 9.35 ± 5.08 | NA | NA | 8.96 ± 3.58 | NA | NA | 5.22 ± 4.86 | NA | NA |
| Others | 6.83 ± 4.00 | NA | NA | 8.51 ± 4.96 | NA | NA | 8.79 ± 3.61 | NA | NA | 4.89 ± 4.53 | NA | NA |
| Economic status | ||||||||||||
| Poor/middle | 7.31 ± 4.24 | NA | NA | 9.23 ± 4.96 | NA | NA | 9.05 ± 3.59 | NA | NA | 5.51 ± 4.83 | NA | NA |
| Good | 7.12 ± 4.20 | NA | NA | 8.52 ± 5.11 | NA | NA | 8.62 ± 3.59 | NA | NA | 4.43 ± 4.45 | NA | NA |
| Marital status | ||||||||||||
| Single | 7.17 ± 4.25 | NA | NA | 8.88 ± 5.01 | NA | NA | 9.01 ± 3.68 | NA | NA | 5.11 ± 4.69 | NA | NA |
| Married | 7.49 ± 4.10 | NA | NA | 9.16 ± 5.15 | NA | NA | 8.24 ± 3.09 | NA | NA | 4.81 ± 4.75 | NA | NA |
| Current department | ||||||||||||
| Emergency/surgery | 8.23 ± 4.59 | NA | NA | 9.92 ± 4.94 | NA | NA | 9.15 ± 3.94 | NA | NA | 5.97 ± 4.87 | NA | NA |
| Internal medicine d | 7.15 ± 4.04 | NA | NA | 8.58 ± 5.04 | NA | NA | 8.83 ± 3.69 | NA | NA | 5.16 ± 4.72 | NA | NA |
| Pediatrics | 8.57 ± 4.60 | NA | NA | 10.00 ± 4.97 | NA | NA | 8.52 ± 2.81 | NA | NA | 5.22 ± 4.81 | NA | NA |
| Gynecology | 7.64 ± 4.02 | NA | NA | 11.77 ± 5.55 | 3.29 ± 1.05 | 0.002 | 10.55 ± 3.50 | 1.65 ± 0.75 | 0.028 | 5.32 ± 4.52 | NA | NA |
| Others | 6.42 ± 4.06 | NA | NA | 8.04 ± 4.72 | Reference | 8.51 ± 3.38 | Reference | 4.34 ± 4.55 | NA | NA | ||
| Accommodation | ||||||||||||
| Dormitory | 5.80 ± 3.56 | -2.60 ± 0.66 | < 0.001 | 7.97 ± 4.75 | -2.06 ± 0.79 | 0.010 | 8.42 ± 3.08 | -1.11 ± 0.56 | 0.047 | 4.23 ± 4.08 | -1.61 ± 0.70 | 0.022 |
| Home with family | 7.51 ± 4.22 | NA | NA | 9.16 ± 5.24 | NA | NA | 8.87 ± 3.75 | NA | NA | 5.07 ± 4.80 | NA | NA |
| Home with friends | 6.21 ± 2.99 | -2.24 ± 1.10 | 0.042 | 7.43 ± 4.42 | -3.06 ± 1.32 | 0.021 | 9.00 ± 3.09 | NA | NA | 6.29 ± 5.62 | NA | NA |
| Home alone | 7.95 ± 4.76 | Reference | 9.46 ± 4.56 | Reference | 9.30 ± 3.65 | Reference | 5.56 ± 4.66 | Reference | ||||
| Interest in medicine | ||||||||||||
| Low | 7.73 ± 4.53 | NA | NA | 9.53 ± 5.44 | NA | NA | 9.03 ± 2.98 | -1.36 ± 0.67 | 0.043 | 5.37 ± 4.00 | -1.68 ± 0.83 | 0.044 |
| Medium | 7.61 ± 4.37 | NA | NA | 9.96 ± 4.938 | NA | NA | 9.57 ± 3.77 | NA | NA | 6.10 ± 4.87 | NA | NA |
| High | 6.76 ± 3.98 | NA | NA | 7.79 ± 4.823 | NA | NA | 8.15 ± 3.39 | Reference | 3.96 ± 4.41 | Reference | ||
| Hope for career prospects | ||||||||||||
| Low | 8.61 ± 4.75 | 1.95 ± 0.68 | 0.004 | 11.31 ± 5.28 | 2.82 ± 0.81 | 0.001 | 10.40 ± 3.89 | 2.06 ± 0.59 | 0.001 | 7.66 ± 5.07 | 2.26 ± 0.74 | 0.002 |
| Medium | 7.05 ± 3.96 | NA | NA | 8.44 ± 4.64 | NA | NA | 8.73 ± 3.28 | 1.08 ± 0.50 | 0.031 | 4.41 ± 4.35 | NA | NA |
| High | 5.69 ± 3.60 | Reference | 6.90 ± 4.57 | Reference | 6.98 ± 3.14 | Reference | 3.20 ± 3.46 | Reference | ||||
| Personal life satisfaction | ||||||||||||
| Low | 9.15 ± 4.69 | 2.32 ± 0.67 | 0.001 | 12.34 ± 4.47 | 4.30 ± 0.77 | 0.001 | 11.64 ± 3.79 | 4.08 ± 0.57 | < 0.001 | 9.00 ± 5.05 | 5.84 ± 0.72 | < 0.001 |
| Medium | 7.38 ± 4.05 | 1.33 ± 0.49 | 0.008 | 8.72 ± 4.70 | NA | NA | 8.97 ± 3.21 | 1.75 ± 0.42 | < 0.001 | 5.10 ± 4.34 | 2.33 ± 0.53 | < 0.001 |
| High | 5.56 ± 3.57 | Reference | 6.96 ± 4.89 | Reference | 6.71 ± 2.72 | 2.18 ± 2.70 | Reference | |||||
| Physical/mental disease | ||||||||||||
| Yes | 8.86 ± 4.49 | 1.69 ± 0.53 | 0.001 | 10.41 ± 5.34 | NA | NA | 10.32 ± 3.96 | 1.03 ± 0.45 | 0.022 | 7.14 ± 5.36 | 1.40 ± 0.56 | 0.013 |
| No | 6.86 ± 4.08 | Reference | 8.60 ± 4.90 | NA | NA | 8.54 ± 3.43 | Reference | 4.59 ± 4.40 | Reference | |||
a Value are presented as mean ± SD.
bValue are presented as β ± SE.
c Not applicable (NA) indicates that the variable was not included in the multivariable regression equation.
dInternal medicine, cardiology, infectious diseases, and toxicology.