An Investigation on the Effect of Alcoholic Extract of Physalis alkekengi on Blood Indexes in Rats

Author(s):
Shahnaz Shekar-ForooshShahnaz Shekar-Foroosh1, Hassan  YarmahmoudiHassan Yarmahmoudi1,*, Hamideh EftekhariHamideh Eftekhari1, Ali ZareAli Zare2, Saeed Changizi-AshtiyaniSaeed Changizi-Ashtiyani3,  Azam Rezaei Azam Rezaei3, Maryam AzizMaryam Aziz3
2Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran
3Department of Physiology, Arak Univer sity of Medical Sciences , Arak, Iran
3Department of Physiology, Arsanjan Branch , Islamic Azad University, Arsanjan, Iran
*Corresponding Author: Department of Physiology, Arsanjan Branch , Islamic Azad University, Arsanjan, Iran Email: [email protected]

Zahedan Journal of Research in Medical Sciences:Vol. 16, issue 10
Published online:Apr 15, 2013
Article type:Brief Report
Received:Mar 07, 2013
Accepted:Apr 24, 2013
How to Cite:Shekar-Foroosh S, Yarmahmoudi H, Eftekhari H, Zare A, Changizi-Ashtiyani S, et al. An Investigation on the Effect of Alcoholic Extract of Physalis alkekengi on Blood Indexes in Rats. Zahedan J Res Med Sci. 2014;16(10):. doi:

Abstract

Background: Physalis alkekengi by effective ingredients such as alkaloids, glucocorticoids and because of antioxidant property can play a role in homeostasis. The aim of this study was to examine the possible effects of fruit extract of P. alkekengi on blood homogram.

Materials and Methods: Forty male rats were divided to control, sham (normal saline) and experimental groups (highest, moderate and minimum doses of alcoholic extract). Then, the blood samples were taken in order to perform laboratory test by Sysmex analyzer, and were analyzed using ANOVA.

Results: Results showed that the number of red blood cells, hemoglobin, hematocrit increased and white blood cells decreased.

Conclusion: Fruit extract of P. alkekensi is probably effective in treatment of anemia.

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© 2014, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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