Zahedan Journal of Research in Medical Sciences
The Official Journal of Zahedan University of Medical Sciences
Nasopharyngeal Mixed Tumor: A Case Report
Author(s):
1Department of ENT, Shar-e-Kord University of Medical Sciences, Shar-e-Kord, Iran
Published online:Dec 27, 2013
Article type:Case Report
Received:May 04, 2013
Accepted:Nov 10, 2013
How to Cite:Reza Khazraei H, Amani S. Nasopharyngeal Mixed Tumor: A Case Report. Zahedan J Res Med Sci. 2014;16(11):e23397. doi:
Abstract
Salivary gland tumors are uncommon neoplasm’s [1] that represent 6-10% of all head and neck neoplasia and 0.3-0.5% of all cancers [2, 3]. The incidence of salivary gland tumors ranges from 0.5 to 2 per 100,000 in different parts of the world [3, 4], with varied biological behavior and clinical outcome [5]. Benign tumors of nasopharynx are rare since nasopharynx is common site for malignant tumors. Pleomorphic adenoma is the most common salivary gland tumor, but is rare in nasopharynx [6].
A 61 years old woman came to the office with 6-month-long progressive nasal obstruction. Anterior rhinos copy and nasal endoscopy were normal but a round mass was seen after the choana, in the posterior wall of nasopharynx. She had hypo nasal voice. Her ears, or pharynx and neck examination were normal; she had par nasal coronal CT and MRI study with herself.
They showed single round mass in the nasopharynx. The mass respected under general anesthesia with adenotome and homeostatic very simply and we did septoplasty too. The patient visited after a week, exiled with nasal endoscopy one and 6 months later. There was not any recurrence.
The fosse of Rosenmuller is a common site of squalors cell carcinoma of the nasopharynx and nasal obstruction, epitasis and neck adenopathy are common symptoms of nasopharyngeal carcinoma [6].
Pleomorphic adenoma or benign mixed tumor makes up 65% of salivary gland tumors [7]. Palate, nasal cavity and nasopharynx have minor salivary glands and pleomorphic adenoma is the most common benign tumor of these glands.
CT scan is not significant differentiation between carcinoma ex pleomorphic adenoma and benign pleomorphic adenoma [6]. Another form of this tumor is salivary gland anlagen tumor (SGAT) of the nasopharynx that is a rare cause of neonatal airway obstruction [8].
Taker et al. reported nasopharyngeal pleomorphic adenoma in a 35 years old male; they said that they found only 5 published reports on this tumor arising from nasopharynx [6]. Lee et al. reported another case of this nasopharyngeal tumor with unilateral nostalgia, tinnitus and aural fullness and a nasopharyngeal pleomorphic adenoma that rose in the soft palate [9]. On the way review of the literature reveals that nasopharyngeal pleomorphic adenoma is rare.
Nasopharyngeal pleomorphic adenoma is a rare tumor, but it must be in mind in the differential diagnosis of nasopharyngeal mass and nasal obstruction. The treatment is surgical removal and fallow up the patient.
Acknowledgments
Footnotes
References
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- 7.Kuo YL, Tu TY, Chang CF, Li WY, Chang SY, Shiao AS, et al. Extra-major salivary gland pleomorphic adenoma of the head and neck: a 10-year experience and review of the literature. Eur Arch Otorhinolaryngol. 2011;268(7):1035-40. [PubMed ID: 21120660]. https://doi.org/10.1007/s00405-010-1437-2.
- 8.Herrmann BW, Dehner LP, Lieu JE. Congenital salivary gland anlage tumor: a case series and review of the literature. Int J Pediatr Otorhinolaryngol. 2005;69(2):149-56. [PubMed ID: 15656947]. https://doi.org/10.1016/j.ijporl.2004.08.014.
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Copyright © 2014 Zahedan University of Medical Sciences. All rights reserved.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
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