Predictors of Recurrent Febrile Seizures in Iranian Children

Background : A few factors appear to boost a child's risk of having recurrent febrile seizures, including young age during the first seizure, seizure type, and having immediate family members with a history of febrile seizures. The present study aimed to provide reliable information about recurrent febrile seizure in Iranian children.
Materials and Methods : On the computerized literature valid on valid keyword with search in valid database PubMed, Scientific Information Databases (SID (, Global medical article limberly (Medlib), Iranian Biomedical Journals (Iran Medex), Iranian Journal Database (Magiran), and Google Scholar recruited in different geographic areas. To explore heterogeneity in studies I2 index was used. Meta-analysis used to data analysis with random effects model.
Results : Hospital data of 4,599 children with febrile seizure. Overall, 21 studies met our inclusion criteria. Febrile seizure in 2 age groups (<2 and 2-6 years) were 55.8% (95% CI: 50.4-61.2) and 44.2% (95% CI: 38.8-61.2) respectively. Pooled recurrent rate of febrile seizure in Iran was 20.9% (95% CI: 12.3-29.5). In 28.8 (95% CI: 19.3-38.4), children there was positive family history. The mean prevalence of simple and complex seizures was 69.3% (95% CI: 59.5-79.0) and 28.3% (95% CI: 19.6-31.0) respectively. The rates in different geographical regions of central, east, and west of Iran, 25, 20.8 and 27.1% were estimated, respectively.
Conclusion : According to the data the prevalence febrile seizure is higher in males and children under two years. Recurrence rate in Iran, similar to other studies performed in other regions of the world.