The Effect of Gundelia Tournefortii Hydro-Alcoholic Extract on Sperm Motility and Testosterone Serum Concentration in Mice

Background: Gundelia tournefortii was used as a food and medicinal in human life from
past time. The present study has been investigated the effects of Gundelia tournefortii on
number and motility of sperms and testosterone serum concentration.
Materials and Methods: In this experimental study, male mice were divided into control
and 4 experimental groups (Gundelia tournefortii extract at doses of 100, 200, 400, 800
mg/kg was administered intraperitoneally for 14 days). One week after the last injection,
blood samples were collected for hormonal assay. Also weight of testes, motility rate and
number of sperms were assessed. Data analysis was performed using one-way ANOVA
followed by Tukey test.
Results: Studies showed the number of sperms increased significantly at dose of 400
mg/kg (2.88±0.4580) (p=0.001).The percentage of sperm motility (p=0.001) and the
testicular weight (p=0.012) significantly increased at doses of 200 (36.83± 1.2506) and
400 mg/kg (57.51±2.1113) (p=0.001). Testosterone serum level significantly increased at
doses of 100 (p=0.05), 200 (p=0.05) and 400 mg/kg (p=0.001) as compared to control
group.
Conclusion: Gundelia tournefortii extract increases the number, motility of sperm and
testosterone level because of antioxidant components for example Quercetin presumably.