The clinicopothologic study of benign and malignant lesions of salivary glands in patients attending Shiraz dental school in 15 years

Background: There are malignant and benign intra-oral pathologic lesions of salivary gland. Reevaluation of paitants’ age, sex and location of lesions can help to have better diagnosis and accurate comparison with other studies in other countries.

  m aterials and Method : In a retrospective study, cases of benign and malignant salivary gland during 1369 to 1385 retrieved from the files and histopathologic records of cases diagnosed at Shiraz School of Dentistry.

  Results : From 110 cases, 70 cases had mucocele, 15 had sialadenitis, 7 of pleomorphic adenoma, 3 mucoepidermoid carcinoma and the remaining 3 cases had adenoid cystic carcinoma. The mean age for patients with mucoceles was 20. 8 and the most common site were mucosa of the lower lips. The mean age for patients with sialadenitis was 34. The most common sites were mucosa of the lips and submandibular gland. The mean age of pleomorphic adenoma was 32 and the most common site was hard palate. Mucoepidermoid carcinoma was detected in 3 males at the ages of 44 to 54. Adenoidcystic carcinoma was seen in 3 patients at the ages of 18 to 32.

  Conclusion: Mucocele was the most common lesion (71%) and pleomorphic adenoma constituted 70% of all salivary gland diseases and 53% of all neoplasms. Mucocele was the most common lesion in lower lip, in the second and third decades with equal gender distribution. Pleomorphic adenoma occurs more in third and fourth decades and the most common site was hard palate.