Fulltext
The full text of this article is available on the PDF file.
Zahedan Journal of Research in Medical Sciences
The Official Journal of Zahedan University of Medical Sciences
e-ISSN 2383-2894
Image Credit:Zahedan J Res Med Sci
Outline
Association of maternal and neonatal plasma interleukin-6 levels in relation to model of delivery
Authors
1Associate Professor of Pediatric, Zahedan University of Medical Sciences and Health Services, Zahedan, Iran.
2Professor of Pediatric, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
3Assistant Professor of Pediatric, Children's Research Center of Infectious, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
4Professor of Pediatric, Children's Research Center of Infectious, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran.
*Corresponding Author: Professor of Pediatric, Children's Research Center of Infectious, Shahid Beheshti University of Medical Sciences and Health Services, Tehran, Iran. Email: dr_a_karimi@yahoo.com
Published online:Apr 13, 2011
Article type:Research Article
Received:Nov 08, 2010
Accepted:Dec 22, 2010
How to Cite:Imani M, Fakhraei S, Afjeh S, Karimi A. Association of maternal and neonatal plasma interleukin-6 levels in relation to model of delivery. Zahedan J Res Med Sci. 2011;13(3):e94009. doi:
Abstract
Background: Cytokines play an important role during labor of full – or pretern delivery. In umbilical cord blood, Interleukin-6 (IL-6) was thought to be a marker of defense to stress, surgery and infection. The aim of this study was to investigate the cytokine IL-6 concentrations in the mother and neonate depends on the mode of the delivery.
Materials and Method: This study was done on mothers and neonates in 80 single term deliveries (vaginal and cesarean) in Mahdieh Hospital in Tehran. Age of mothers was 21-39 years old, parity was 1 and 2. There wasn't history of underlying disease and drug usage in mothers and neonate was AGA and apgar was more than 8. There wasn't clinical evidence of infection in neonate and mothers. IL-6 was evaluated by enzyme-immunoassays in maternal serum and neonatal umbilical cord. Data were analyzed with SPSS and were applied fishers exact test for compare means.
Results: There were 37 vaginal deliveries and 43cesarean section. The mean (±standard error) of maternal IL-6 concentration in vaginal delivery (0.18±0.02) was significantly (P=0.000) higher than cesarean section (0.1±0.02) and neonatal IL-6 concentration in vaginal delivery (0.17±0.03) was significantly (P=0.000) higher than cesarean section (0.07±0.01).
Conclusion: Results show that vaginal delivery cause to increase IL-6 compared to cesarean section in mother and neonate.
Highlights
References
- 1.The References of this article are available on the PDF file.
Copyright
© 2011, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Similar Articles
28
Oct
2012
Role of Cervical IL-6 and IL-8 Levels in Preterm Labor in Nulliparous Pregnant Women
Sholeh Shahgheibi,
Abdorrahim Afkhamzadeh,
Narjes Noori
Shahgheibi S, Afkhamzadeh A, Noori N. Role of Cervical IL-6 and IL-8 Levels in Preterm Labor in Nulliparous Pregnant Women. Zahedan J Res Med Sci. 2013;15(2):e93083. doi:
1
Dec
2013
Predictive Value of Interleukin-6 (IL6) in Term Neonates With Early Sepsis During 2010-2011
Marzie Heidarzadeh Arani,
Amirhosein Movahedian,
Mohammad Ghannaee Arani,
Mojtaba Adinah,
Ziba Mosayebi
Heidarzadeh Arani M, Movahedian A, Ghannaee Arani M, Adinah M, Mosayebi Z. Predictive Value of Interleukin-6 (IL6) in Term Neonates With Early Sepsis During 2010-2011. Jundishapur J Microbiol. 2013;6(10):e8580. doi: https://doi.org/10.5812/jjm.8580
31
Oct
2006
Maternal and Neonatal Oxytocin Levels During Cesarean Section With or Without Labor Pain and Puerperal Complications
M Sayyah Melli,
M Alizadeh,
M Rahbani-noubar
Sayyah Melli M, Alizadeh M, Rahbani-noubar M. Maternal and Neonatal Oxytocin Levels During Cesarean Section With or Without Labor Pain and Puerperal Complications. Int J Endocrinol Metab. 2006;4(4):. doi:
20
Aug
2025
Comparison of Serum Interleukin 6, Leptin, and Adiponectin Levels after Cesarean Section Under General Versus Spinal Anesthesia
Thaer Kareem Oleiwi Atabi,
Ali Jabbari,
Parvaneh Ebrahimzadeh,
Hamzeh Bader Gazal,
Somayeh Ghorbani Gholiabad,
Ali Movafegh
Kareem Oleiwi Atabi T, Jabbari A, Ebrahimzadeh P, Bader Gazal H, Ghorbani Gholiabad S, et al. Comparison of Serum Interleukin 6, Leptin, and Adiponectin Levels after Cesarean Section Under General Versus Spinal Anesthesia. Anesth Pain Med. 2025;15(4):e162647. doi: https://doi.org/10.5812/aapm-162647
4
Nov
2018
The Effect of Spinal and General Anesthesia on Cytokine Serum Levels Following Cesarean Section in Preeclampsia
Mohammadreza Moshari,
Samira Rajaei,
Maryam Vosoughian,
Hedayatollah Elyasi
Moshari M, Rajaei S, Vosoughian M, Elyasi H. The Effect of Spinal and General Anesthesia on Cytokine Serum Levels Following Cesarean Section in Preeclampsia. J Cell Mol Anesth. 2018;3(3):e149563. doi: https://doi.org/10.22037/jcma.v3i3.22580
Cited by
- Scopus by DOI: 0
Last Update: 3 weeks ago
- Scopus by Title: 0
Last Update: 3 weeks ago
- Scopus by Title (Ref): 1
Last Update: 3 weeks ago
- CrossRef: 0
Last Update: 4 hours ago
- OpenAlex: 0
Last Update: 1 day ago
- OpenCitations: 0
Last Update: 4 days ago
Comments
Number of Comments:0