Official Journal of Research Center for Gastroenterology and Liver Diseases
Authors
Genotype G is the least common of all the hepatitis B virus (HBV) genotypes. The existence of the genotype G strain of HBV was first noted in 2000 and little information is available on its global geographical distribution. Previous studies have demonstrated the dominance of genotype D in patients with HBV infections in Turkey.
To report for the first time in Turkey, the case of a 61 year old male patient who developed the HBV genotype G infection.
According to HBV genotyping using phylogenetic analysis and an INNO-LiPA assay, the patient was infected with genotype G and G+A, respectively.
The present clinical study suggests that the transmission of an HBV genotype other than genotype D, namely HBV genotype G, is possible in Turkey. Epidemiological and clinical information on genotype G infection is currently limited, and this is most likely due to its low prevalence throughout the world. Therefore, it may be important to determine the epidemiologic and molecular characteristics of the HBV genotype G as it relates to chronic hepatitis, to enable better understanding of its circulation and progression around the world.
© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Neisi N, Makvandi M, Samarbaf-Zadeh AR. A study on genotypes of hepatitis B virus among hemodialysis patients in Khuzestan province. Jundishapur J Microbiol. 2011;4(2):. doi:
Mohebbi S, Olyaee S, Zali N, Derakhshan F, Sabahi F, et al. An Extremely Aberrant Subtype of Hepatitis B Virus Genotype D in Iran. Hepat Mon. 2009;9(1):. doi:
Yoosefi K, Taheri M, Khosravi S, Saneie-Moghadam E, Mohagheghi-Fard AH. Genotyping of Hepatitis B Virus by Multiplex PCR in Sistan and Baluchestan Province. Zahedan J Res Med Sci. 2016;18(2):e5986. doi: https://doi.org/10.17795/zjrms-5986
Ozer A, Yakupogullari Y, Beytur A, Beytur L, Koroglu M, et al. Risk factors of hepatitis B virus infection in Turkey: A population-based, case-control study. Hepat Mon. 2011;11(4):. doi:
Azad AR, Zargar M, Zolfaghari MR, Mohammadbeigi A. The Prevalence of Hepatitis B and D Viruses and Evaluating YMDD Mutation in HBV-Suspected Patients in Qom Province, Iran. Jundishapur J Microbiol. 2020;13(2):e100038. doi: https://doi.org/10.5812/jjm.100038
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