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International Journal of Endocrinology and Metabolism
Research Institute for Endocrine Sciences
e-ISSN 1726-9148
p-ISSN 1726-913X
Cushing's Syndrome Accompanied with Adrenal and Pancreatic Mass: A Case Report
Authors
1Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University (MC), [email protected], IR.Iran
2Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University (MC), IR.Iran
*Corresponding Author: Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University (MC), [email protected], IR.Iran. Email: [email protected]
Published online:Jul 31, 2008
Article type:Case Report
Received:Jan 26, 2008
Accepted:Aug 04, 2008
How to Cite:Amouzegar A, Ghanei A, Azizi F. Cushing's Syndrome Accompanied with Adrenal and Pancreatic Mass: A Case Report. Int J Endocrinol Metab. 2008;6(3):. doi:
Abstract
Cushing's syndrome results from inappropriate excessive endogenous glucocorticoids secretion. It may be due to ACTH-producing pituitary adenoma, Adrenocortical adenoma, iatrogen glu-cocorticoid use, or ectopic ACTH production. Pa-tients, who remain untreated, have high morbid-ity and a significant mortality. We describe a very challenging case of Cushing's syndrome due an adrenal adenoma on a pancreatic mass. Material and Methods: A 20-year-old woman presented with sign and symptoms of Cushing syndrome. Thorough basal and dynamic hor-monal assessment. In addition, the results of im-aging studies are presented. Results: The source of ACTH secretion was adrenal adenoma, and hypercortisolism was con-trolled by adrenalectomy. A unique feature of this case is the fact that we observed an adrenal adenoma as a source of Cushing syndrome and an incidental nonfunctional pancreatic nesidiob-lastosis. Conclusion: The diagnosis of Cushing's syn-drome may turn out to be sometimes a complex and time-consuming challenge in clinical endo-crinology.
Copyright
© 2008, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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