Resistin in Cord Blood of Small for Gestation Age and Appropriate for Gestation Age Term Neonates

Manizheh  Mostafa-Gharehbaghi; Sina Davari Farid; Naiere Najati; Ali Ghorbani Haghjo; Morteza Ghojazadeh

IJ Pediatrics

The Scientific Journal of Growth & Development Research Center

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Resistin in Cord Blood of Small for Gestation Age and Appropriate for Gestation Age Term Neonates

Author(s):

Manizheh Mostafa-Gharehbaghi^1,*,

Sina Davari Farid²,

Naiere Najati³,

Ali Ghorbani Haghjo⁴,

Morteza Ghojazadeh⁵

IJ Pediatrics:Vol. 23, issue 6; 659-663

Published online:Nov 03, 2013

Article type:Research Article

Received:Nov 27, 2012

Accepted:Sep 11, 2013

How to Cite:Manizheh Mostafa-GharehbaghiSina Davari FaridNaiere NajatiAli Ghorbani HaghjoMorteza GhojazadehResistin in Cord Blood of Small for Gestation Age and Appropriate for Gestation Age Term Neonates.Iran J Pediatr.23(6):659-663.

Abstract

Objective: Placental hormones such as resistin, adiponectin, ghrelin and leptin are known to have considerable role in fetal growth and there are some articles published in this area recently. Nevertheless there is a shortage of data showing association between resistin level and fetal growth; that was why we decided to conduct a study to evaluate this association. Methods: This study was approved by ethic committee of pediatric health research center and research vice chancellor of Tabriz University of Medical Sciences. In this case-control study we measured the insulin, glucose and resistin in the cord blood of neonates with gestational age of 37 weeks or more in Al Zahra tertiary hospital from March 2011 to March 2012. Thirty-nine appropriate for gestation age (AGA) neonates and 41 small for gestation age (SGA) neonates were studied. Findings: The umbilical cord blood resistin level was not found to have significant correlation with the type of delivery [normal vaginal delivery (NVD) or cesarean-section (C-S)], neonate's gender, maternal age or body mass index (BMI). There was no significant difference in the levels of Insulin and glucose between AGA and SGA groups. Resistin level of blood cord in AGA group was 613.76±180.10 (range: 132.6-983.80 ng/ml) and in SGA group it was 1303.47±537.07 (range: 800.9-3001 ng/ml) (P

Keywords

Small for Gestational Age

Appropriate for Gestational Age

Resistin

Insulin

Glucose

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