Blood Eosinophil Levels in Newborns with Severe Indirect Hyperbilirubinemia Treated with Phototherapy

Banu Aydın Aydın; Serdar Beken; Ayşegül  Zenciroğlu; Dilek Dilli; Nurullah Okumuş

IJ Pediatrics

The Scientific Journal of Growth & Development Research Center

Outlines

Abstract
References
Copyright

Blood Eosinophil Levels in Newborns with Severe Indirect Hyperbilirubinemia Treated with Phototherapy

Author(s):

Banu Aydın Aydın¹,

Serdar Beken^2,*,

Ayşegül Zenciroğlu³,

Dilek Dilli⁴,

Nurullah Okumuş ⁵

IJ Pediatrics:Vol. 24, issue 3; 267-272

Published online:May 08, 2014

Article type:Research Article

Received:Oct 20, 2013

Accepted:Mar 24, 2014

How to Cite:Banu Aydın AydınSerdar BekenAyşegül ZenciroğluDilek DilliNurullah Okumuş Blood Eosinophil Levels in Newborns with Severe Indirect Hyperbilirubinemia Treated with Phototherapy.Iran J Pediatr.24(3):267-272.

Abstract

Objective: Newborns who suffer from jaundice and/or receive phototherapy (PT) are at a higher risk of developing asthma. In this study we aimed to investigate the relationship between bilirubin and peripheral eosinophil counts in newborns with severe hyperbilirubinemia needing PT.Methods: In this study, a retrospective analysis was performed on 306 newborns with severe hyperbilirubinemia with gestational age ≥35 weeks (Group 1) and the control group consisted of 295 age and gender-matched newborns (Group 2). Total serum bilirubin, hemoglobin, albumin, leucocyte and eosinophil counts before and after PT were recorded from medical charts.Findings: All the patients in Group 1 received phototherapy and 77 (25.2%) of them needed exchange transfusion (ET). Before receiving PT, the patients in Group 1 had lower levels of Hb and higher levels of total serum bilirubin and lymphocytes than those in Group 2 although there was no statistically significant difference with regard to peripheral eosinophil counts. Eosinophils were detected to be numerically lower in Group 1. Higher bilirubin subgroups had also lower eosinophil counts. The patients in Group 1 had lower levels of Hb, leucocyte, albumin and higher levels of eosinophil following PT.Conclusion: Peripheral eosinophil count may be affected by bilirubin levels and/or phototherapy. There is a need for further clinical research based on different models.

Keywords

Fulltext

Click here to download PDF.

References

1.
References are available on the PDF.

comments