Application of the Phenomenological Model to Electrophoretic Mobility in Mixed Solvent Electrolyte Systems in Capillary Zone Electrophoresis

authors:

avatar Abolghasem Jouyban 1 , * , avatar Hak-Kim Chan 2 , avatar Maryam Khoubnasabjafari 3

School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Faculty of Pharmacy, The University of Sydney, Sydney, Australia
Kimia Research Institute, Tabriz, Iran
Iranian Journal of Pharmaceutical Research: Vol.3, issue 1; 23-27
published online: November 20, 2010
article type: Research Article
received: July 01, 2003
accepted: January 01, 2004
DOI: https://doi.org/10.22037/ijpr.2010.292

how to cite: Jouyban A, Chan H, Khoubnasabjafari M. Application of the Phenomenological Model to Electrophoretic Mobility in Mixed Solvent Electrolyte Systems in Capillary Zone Electrophoresis. Iran J Pharm Res. 2004;3(1):e127978. https://doi.org/10.22037/ijpr.2010.292.

Abstract

The phenomenological model of Khossravi and Connors (1992) has been adopted to calculate the electrophoretic mobility of drugs at different concentrations of solvents in a binary mixture. The accuracy and predictability of the model have been evaluated employing 14 experimental data sets by using average percentage mean deviation (APMD). The obtained APMD for correlative and predictive studies are within an acceptable error range and the results show that the model can be used in method development stage to speed up the optimisation process.