Application of the Phenomenological Model to Electrophoretic Mobility in Mixed Solvent Electrolyte Systems in Capillary Zone Electrophoresis

Authors

Abolghasem Jouyban1,*, Hak-Kim Chan2, Maryam Khoubnasabjafari3
1School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2Faculty of Pharmacy, The University of Sydney, Sydney, Australia
3Kimia Research Institute, Tabriz, Iran
*Corresponding Author: School of Pharmacy and Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Email:[email protected]

IJ Pharmaceutical Research:Vol. 3, issue 1; 23-27
Published online:Nov 20, 2010
Article type:Research Article
Received:Jul 01, 2003
Accepted:Jan 01, 2004
How to Cite:Jouyban A, Chan H, Khoubnasabjafari M. Application of the Phenomenological Model to Electrophoretic Mobility in Mixed Solvent Electrolyte Systems in Capillary Zone Electrophoresis. Iran J Pharm Res. 2004;3(1):e127978. doi: https://doi.org/10.22037/ijpr.2010.292

Abstract

The phenomenological model of Khossravi and Connors (1992) has been adopted to calculate the electrophoretic mobility of drugs at different concentrations of solvents in a binary mixture. The accuracy and predictability of the model have been evaluated employing 14 experimental data sets by using average percentage mean deviation (APMD). The obtained APMD for correlative and predictive studies are within an acceptable error range and the results show that the model can be used in method development stage to speed up the optimisation process.

Copyright

© 2004, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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