The Correlation between Echocardiographic Findings and QT Interval in Cirrhotic Patients

Alireza  Moaref; Mahmood Zamirian; Maryam  Yazdani; Oveis  Salehi; Mehrab Sayadi; Kamran Aghasadeghi

International Cardiovascular Research Journal

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

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The Correlation between Echocardiographic Findings and QT Interval in Cirrhotic Patients

Author(s):

Alireza Moaref^1,*,

Mahmood Zamirian¹,

Maryam Yazdani¹,

Oveis Salehi¹,

Mehrab Sayadi¹,

Kamran Aghasadeghi¹

1Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

International Cardiovascular Research Journal:Vol. 8, issue 2; e12027

Published online:Jun 30, 2014

Article type:Research Article

Received:Apr 29, 2017

Accepted:Jan 11, 2014

How to Cite:Alireza MoarefMahmood ZamirianMaryam YazdaniOveis SalehiMehrab SayadiKamran Aghasadeghiet al.The Correlation between Echocardiographic Findings and QT Interval in Cirrhotic Patients.Int Cardiovasc Res J.8(2):e12027.

Abstract

Background:: Although many electrocardiographic abnormalities have been reported previously, prolonged QTC interval represented as the most important ECG finding in patients with liver cirrhosis. Echocardiography can detect structural cardiac abnormalities in cirrhotic patients.

Objectives:: The present study aimed to determine the correlation between QTC prolongation and echocardiographic findings in end stage liver cirrhosis.

Methods:: The present study was conducted on 100 patients selected through convenient sampling. We recruited 80 cirrhotic patients with CHILD score > B or MELD score > 15 from the transplantation ward of Nemazee educational hospital. A complete echocardiographic study, including chamber quantification, a complete flow Doppler, and tissue Doppler analysis, was performed for each patient using a GE vivid 3 system equipped with Tissue Doppler Imaging (TDI). Then, twelve-lead ECG was carried out and QTc interval was calculated in all patients. The data were analyzed using the SPSS statistical software (v. 13) and Pearson’s correlation coefficient. P value < 0.05 was considered statistically significant.

Results:: The patients’ age ranged from 20 to 60 years old and 62.5% of them were male. According to the results, the only parameter which was significantly associated with prolonged QTc interval was Left Ventricular End Diastolic Dimension (LVEDD). Additionally, a linear direct relationship was found between corrected QT interval and LVEDD (r = 0.41, P < 0.001).

Conclusions:: The current study showed a positive correlation between QTC prolongation as an electerocardiographic finding and LVEDD in echocardiography of the cirrhotic patients. This may indicate a direct relationship between the electrophysiological problems and the severity of volume overload in cirrhotic patients.

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