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International Cardiovascular Research Journal
The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences
e-ISSN 2251-9149
p-ISSN 2251-9130
Outline
Relationship between Renal Artery Stenosis and Severity of Coronary Artery Disease in Patients with Coronary Atherosclerotic Disease
Authors
Amirfarhang Zandparsa1, Mehrdad Habashizadeh1,*, Ehsan Moradi Farsani1, Mostafa Jabbari1, Razieh Rezaei1
1Department of Cardiology, Tehran University of Medical Sciences, Tehran, Iran
*Corresponding Author: Corresponding author: Mehrdad Habashizadeh, Department of Cardiology, Tehran University of Medical Sciences, Tehran, Iran Email: [email protected]
Published online:Sep 30, 2012
Article type:Research Article
Received:May 16, 2017
Accepted:Jul 12, 2012
How to Cite:Zandparsa A, Habashizadeh M, Moradi Farsani E, Jabbari M, Rezaei R. Relationship between Renal Artery Stenosis and Severity of Coronary Artery Disease in Patients with Coronary Atherosclerotic Disease. Int Cardiovasc Res J. 2017;6(3):e12803. doi:
Abstract
Objective: The aim of the present investigation was to explore probable association of renal artery stenosis (RAS) with coronary artery disease (CAD) and the prevalence of renal artery stenosis (RAS) in patients with CAD.
Patients and methods: This study comprised 165 consecutive patients with CAD, including 52.7% males and 47.2% females with respective mean ages of 60.3 ±8.9 and 59.5±10.1. The patients underwent simultaneous coronary and renal angiographies, and the lumen reduction of 50% or more was considered as significant stenosis. Indeed, stenosis of more than 70% of the arterial lumen was regarded as severe.
Results: According to our findings, the prevalence of renal artery stenosis in our hypertensive and normotensive patients were 46.2% and 19.5% respectively (p=0.002). Renal artery angiography revealed that 64 (38.8%) of the patients had simultaneous renal artery stenosis. RAS is more common in females than males (p=0.031). Multivariate analysis revealed that among all examined factors, hypertension and serum creatinine were associated with RAS. There was no correlations found between gensini score and RAS (p=0.63).
Conclusion: We found a relatively high prevalence of RAS including 46.2% in hypertensive and 19.5% in normotensive patients in our patients with CAD.
Highlights
References
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Copyright
© 2017, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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