academic journalism

Effect of Professional Exercises on Brain Natriuretic Peptide


avatar H Sheikhani Shahin 1 , avatar Mohammad Ali Babaee Bigi 2 , avatar Amir Aslani 2 , * , avatar F Daryanoosh 1

1 Education School, Shiraz University of Medical Scinces, Shiraz, Iran, Iran

2 Cardiovascular Research Center, Shiraz University of Medical Scinces, Shiraz, Iran, Iran

How to Cite: Sheikhani Shahin H , Babaee Bigi M A , Aslani A, Daryanoosh F . Effect of Professional Exercises on Brain Natriuretic Peptide. Int Cardio Res J. 2009;3(4):e67880.


International Cardiovascular Research Journal: 3 (4); e67880
Published Online: December 31, 2009
Article Type: Research Article
Received: February 26, 2018
Accepted: December 31, 2009


Background: Brain natriuretic peptide (BNP) reflects myocardial wall stress. BNP activities are similar to those
of atrial natriuretic peptide, including diuresis, natriuresis, hypotension and smooth muscle relaxation as well
as ability to inhibit the rennin aldosterone system. It is mainly produced and released into the circulation by
the ventricle in response to increased ventricular wall pressure or stretching. Therefore, BNP can be served as
a marker of left ventricular dysfunction. The aim of this study was to investigate effect of various professional
exercises on plasma BNP levels.
Methods: We enrolled 20 consecutive healthy professional athletic males from different sporting disciplines including
5 football players, 5 volleyball players, 5 bodybuilders and 5 water- polo players. Plasma BNP samples
were taken immediately before and 1 hour after exercise.
Results: Plasma BNP level was significantly increased after exercise (30.01 ± 23.46 vs. 16.72 ± 10.86 pg/ml;
P= 0.042). The highest increase in BNP level was found among volleyball players (mean values: 19.12 to 43.38
pg/ml; 126.3% increase after volleyball) compared to other exercises.
Conclusion: Exercise can increase plasma BNP levels, particularly among volleyball players.


The full text is available in PDF.


  • 1.

    The references are available in PDF.

© 2009, Shiraz University of Medical Sciences.