Abstract
Background: Atrial fibrillation is the most common arrhythmic complication after coronary artery bypass
grafting. Ischemic preconditioning has proved to be a potent endogenous factor in suppressing ischemia- reperfusion
induced arrhythmia.
Patients and Methods: In this prospective study, 101 patients were randomly selected and divided into two
groups including 50 patients with ischemic preconditioning protocol and 51 patients in the control group. Data
were collected from 24 hour electrocardiogram from 1 day before the operation to 3rd post-operative day. Atrial
fibrillation was registered as positive, if it lasted longer than 30 seconds.
Results: The postoperative atrial fibrillation was significantly lower in the ischemic preconditioning group that
was 8% in ischemic preconditioning and 23.52% in control groups (P=0.033). Control group had a longer stay
in intensive care unit and longer mechanical ventilation support.
Conclusion: This study suggests that ischemic preconditioning is a useful prophylactic protocol to decrease the
prevalence of post-cardiac surgery atrial fibrillation.
grafting. Ischemic preconditioning has proved to be a potent endogenous factor in suppressing ischemia- reperfusion
induced arrhythmia.
Patients and Methods: In this prospective study, 101 patients were randomly selected and divided into two
groups including 50 patients with ischemic preconditioning protocol and 51 patients in the control group. Data
were collected from 24 hour electrocardiogram from 1 day before the operation to 3rd post-operative day. Atrial
fibrillation was registered as positive, if it lasted longer than 30 seconds.
Results: The postoperative atrial fibrillation was significantly lower in the ischemic preconditioning group that
was 8% in ischemic preconditioning and 23.52% in control groups (P=0.033). Control group had a longer stay
in intensive care unit and longer mechanical ventilation support.
Conclusion: This study suggests that ischemic preconditioning is a useful prophylactic protocol to decrease the
prevalence of post-cardiac surgery atrial fibrillation.
Keywords
Ischemic Preconditioning Atrial Fibrillation Coronary Artery Bypass Grafting
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Copyright
© 2009, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.