Cover image of the article: Biological evaluation of Hippuric Acid concentration from metabolite of Toluene in urine of gas stations workers

Image Credit:J Inflamm Dis

Biological evaluation of Hippuric Acid concentration from metabolite of Toluene in urine of gas stations workers

Authors

A Bahrami, H Mahjub,*, MJ Asari
*Corresponding Author: Email: hmahjub@mail.com

Journal of Inflammatory Diseases:Vol. 5, issue 2; 17-21
Published online:Sep 30, 2001
Article type:Research Article
How to Cite:Bahrami A, Mahjub H, Asari M. Biological evaluation of Hippuric Acid concentration from metabolite of Toluene in urine of gas stations workers. J Inflamm Dis. 2024;5(2):e154817. doi:

Abstract

Background: Toluene and xylene are compounds of petrol that emit to ambient air through car exhaust pipe and affect humans’ health. The biological factor for toluene and xylene is hippuric acid that is excreted in the urine. Objective: To determine the biological concentration of hippuric acid in urine of workers occupied in gas pump stations. Methods: 46 samples (23 before and 33 after working shifts) were collected and analyzed by spectrophotometer to determine the concentration of hippuric acid and creatinine. Findings: The mean concentration of hippuric acid in workers’ urine before and after working hours were 0.116 and 0.95 gram per gram creatinine respectively thus no significant difference was shown. The concentration of hippuric acid in workers urine in afternoon shift was more than the morning shift (P=0.032). Also, the mean concentration of hippuric acid in workers less than 10 years occupancy was more than the other workers (P=0.002). Conclusion: The concentration of hippuric acid in urine was less than the biological exposure determined by American conference governmental industrial hygiene.

Highlights

Copyright

© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.

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