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Jundishapur Journal of Microbiology
Ahvaz Jundishapur University of Medical Sciences
e-ISSN 2008-4161
p-ISSN 2008-3645
Genotyping and identification of mycobacteria by fingerprinting techniques
Authors
1Department of Medical Microbiology, School of Medicine, and Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, [email protected], Iran
2Department of Medical Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Iran
*Corresponding Author: Department of Medical Microbiology, School of Medicine, and Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, [email protected], Iran. Email: [email protected]
Published online:Jul 31, 2009
Article type:Research Article
Received:Jul 01, 2009
Accepted:Sep 01, 2009
How to Cite:Khosravi AD, Seghatoleslami S. Genotyping and identification of mycobacteria by fingerprinting techniques. Jundishapur J Microbiol. 2009;2(3):. doi:
Abstract
Tuberculosis (TB) remains a worldwide healthcare concern and has been characterized as an epidemic by World Health Organization (WHO). In the last few decades, DNA fingerprint techniques have become available to study the transmission of TB and other mycobacterial infections. The main gold standard typing technique is restriction fragment length polymorphism, which is widely used for molecular epidemiology purposes. However, other recently introduced techniques such as spoligotyping and MIRU-VNTR are also widely used. This review briefly summarizes the recent achievements in TB epidemiology associated with the introduction of molecular typing methods for Mycobacterium tuberculosis complex and non-M. tuberculosis complex mycobacteria. Besides, in this article, the application of molecular methods in the study of epidemiological aspects and diagnosis of mycobacterial diseases are highlighted.
Copyright
© 2009, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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