Journal of Kermanshah University of Medical Sciences
Peer-reviewed Medical Quarterly
e-ISSN 2588-2570
p-ISSN 2588-2562
Outline
Induction of growth and proliferation of fibroblast cells in magnetic field
Authors
1Dept. of Biology, School of Basic Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
2Dept. of Pilot Biotechnology, Pasteur Institute of Iran, Tehran, Iran
*Corresponding Author: Corresponding author: Seyed Mohammad Atyabi, Dept. of Pilot Biotechnology, Pasteur Institute of Iran, Tehran, Iran, Tel: +98 2164112165 Email: [email protected]
Published online:Feb 20, 2015
Article type:Research Article
Received:Aug 11, 2014
Accepted:Jan 20, 2015
How to Cite:Ezatti N, Irani S, Atyabi SM. Induction of growth and proliferation of fibroblast cells in magnetic field. J Kermanshah Univ Med Sci. 2015;18(11):e73995. doi: https://doi.org/10.22110/jkums.v18i11.1874
Abstract
Background: Tissue engineering is generally defined as developing and changing the laboratory growth of molecules and cells in tissues or organs to replace and repair the damaged part of body. This study was carried out to stimulate the growth of cultured fibroblast cells by a physical electromagnetic method.
Methods: First, an air-core coil was prepared and the cell culture plate was placed comfortably into the mold, then the plate containing the culture medium and human fibroblast cell along with air-core coil were placed in an incubator and then connected to the power supply. Thus, the sample underwent electromagnetic field at different times, and cell proliferation was studied by MTTassay.
Results: Microscopic images indicated that the cells undergoing electromagnetic field (0.35 amps) had a significant growth compared to the cells in control group in a definit range of stimulation.
Conclusion: In conclusion, electromagnetic stimulation in a definite range led to cell proliferation and could be used as a positive factor in tissue engineering.
Highlights
References
- 1.The references of this article is available on PDF.
Copyright
© 2015, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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