Logo

Relationship between synthesis of P21 and Cyclin D1 proteins and histomorphometric parameters of mice testicular tissue in presence of Aflatoxin G1

Author(s):
Cyrus JaliliCyrus Jalili, Toraj Zamir-NastaToraj Zamir-Nasta, laya ghaharilaya ghahari,*, Seyran Kakeh baraeiSeyran Kakeh baraei

Koomesh:Vol. 21, issue 1; 195-200
Published online:Mar 01, 2019
Article type:Research Article
Received:Dec 03, 2017
Accepted:Jul 01, 2018
How to Cite:Cyrus JaliliToraj Zamir-Nastalaya ghahariSeyran Kakeh baraeiRelationship between synthesis of P21 and Cyclin D1 proteins and histomorphometric parameters of mice testicular tissue in presence of Aflatoxin G1.koomesh.21(1):e153057.

Abstract

References

  • 1.
    Luo J, Vogel RF, Niessen L. Rapid detection of aflatoxin producing fungi in food by real-time quantitative loop-mediated isothermal amplification. Food Microbiol 2014;44:142-148.
  • 2.
    Moeenian k, Yaghmaeian K, Ghorbani R. Aflatoxin M1 concentration in raw milk produced in the cities of Semnan province Iran. Koomesh 2014; 15:176-181. (Persian).
  • 3.
    Sharlin JS, Howarth B Jr, Thompson FN, Wyatt RD. Decreased reproductive potential and reduced feed consumption in mature white leghorn males fed aflatoxin. Poultry Sci 1981; 60:2701-278.
  • 4.
    Luo J. Detection, Identification, and quantification of aflatoxin producing fungi in food raw materials using loop-mediated isothermal amplification (LAMP) Assays. 2014.
  • 5.
    Sanjarani A. The study of aflatoxin types and methods of detection, purification, identificationand their effects on human and animal. Sci RoadJ 2015; 3:229-235.
  • 6.
    Khan MR, Alothman ZA, Ghfar AA, Wabaidur SM. Analysis of aflatoxins in nonalcoholic beer using liquid-liquid extraction and ultraperformance LC-MS/MS. J Sep Sci2013; 36:572-577.
  • 7.
    Liu Y, Wu F. Global burden of aflatoxin-induced hepatocellular carcinoma: a risk assessment. Environ Health Perspect2010; 118:818-824.
  • 8.
    Zhang X, Wang F, Wang J, Yan X, Huang X, Xie T, et al. [Experimental lung carcinoma induced by fungi and mycotoxins--a review]. Beijing Da Xue Xue Bao Yi Xue Ban2003; 35:4-6.
  • 9.
    Supriya C, Girish BP, Reddy PS. Aflatoxin B1-induced reproductive toxicity in male rats: possible mechanism of action. Int J Toxicol 2014; 33:155-161.
  • 10.
    Hasanzadeh SR. Effects of aflatoxin B1 on the growth processes of spermatogenic cell series in adult male rats. Comparat Clin Pathol 2013; 22: 555-562.
  • 11.
    Cao Z, Shao B, Xu F, Liu Y, Li Y, Zhu Y. Protective effect of selenium on aflatoxin B1-induced testicular toxicity in mice. Biol Trace Elem Res 2017; 180:233-238.
  • 12.
    Zamir Nasta T, Razi M, Hassanzadeh S, Malekinejad H. Effect of aflatoxin B1 on histomorphometric parameters of testis in male mature albino mouse. Qom Univ Med Sci J 2017; 11:10-17. (Persian).
  • 13.
    Mukumu CK, MachariaBN. Effects of aflatoxin b1 on liver, testis, and epididymis of reproductively mature male pigs: Histopathological evaluation. East African Med J 2017; 94.
  • 14.
    Thnaian Althnaian IAaSME-B. Effect of aflatoxin B1 on histopathology and oxidative stress biomarkers in testis of rats with special references to gene expression of antioxidant enzymes. Int J Pharmacol 2016; 12:408-414.
  • 15.
    Ioachim E, Michael M, Stavropoulos NE, Kitsiou E, Hastazeris K, Salmas M, et al. Expression patterns of cyclins D1, E and cyclin-dependent kinase inhibitors p21(Waf1/Cip1) and p27(Kip1) in urothelial carcinoma: correlation with other cell-cycle-related proteins (Rb, p53, Ki-67 and PCNA) and clinicopathological features. Urol Int 2004; 73:65-73.
  • 16.
    Dong P, Zhang C, Parker BT, You L, Mathey-Prevot B. Cyclin D/CDK4/6 activity controls G1 length in mammalian cells. PloS One 2018; 13:e0185637.
  • 17.
    Alves MR, NC EM, Barros-Filho MC, do Amaral NS, Silva FIB, Baiocchi Neto G, et al. Downregulation of AGR2, p21, and cyclin D and alterations in p53 function were associated with tumor progression and chemotherapy resistance in epithelial ovarian carcinoma. Cancer Med 2018.
  • 18.
    Murad A. Toxicity effect of aflatoxin B1 on reproductive system of albino male rats. Pakistan J Biol Sci 2015; 18:107-114.
  • 19.
    El-Kordy EAAG, Maha M. Effect of aflatoxin B1 on the seminiferous tubules and the possible protective role of curcumin in adult albino rats (Light and electron microscopic study). Egy J Histol 2015; 38: 614-628.
  • 20.
    Yi L, Shen H, Zhao M, Shao P, Liu C, Cui J, et al. Inflammation-mediated SOD-2 upregulation contributes to epithelial-mesenchymal transition and migration of tumor cells in aflatoxin G1-induced lung adenocarcinoma. Sci Rep 2017; 7:7953.
  • 21.
    Shen H, Liu C, Shao P, Yi L, Wang Y, Mills Ko E, et al. Enhanced phenotypic alterations of alveolar type II cells in response to Aflatoxin G1 -induced lung inflammation. J Cell Physiol 2015; 230:1199-1211.
  • 22.
    Liu C, Shen H, Yi L, Shao P, Soulika AM, Meng X, et al. Oral administration of aflatoxin G(1) induces chronic alveolar inflammation associated with lung tumorigenesis. Toxicol Lett 2015; 232:547-556.
  • 23.
    Ortatatli M, Ciftci MK, Tuzcu M, Kaya A. The effects of aflatoxin on the reproductive system of roosters.Res Vet Sci 2002; 72:29-36.
  • 24.
    Agnes VF, Akbarsha MA. Spermatotoxic effect of aflatoxin B(1) in the albino mouse. Food Chem Toxicol 2003; 41:119-130.
  • 25.
    Olashaw N, Pledger WJ. Paradigms of growth control: relation to Cdk activation. Sci STKE 2002; 2002:re7.
  • 26.
    Matsuura I, Denissova NG, Wang G, He D, Long J, Liu F. Cyclin-dependent kinases regulate the antiproliferative function of Smads. Nature 2004; 430:226-231.
  • 27.
    Tashiro E, Tsuchiya A, Imoto M. Functions of cyclin D1 as an oncogene and regulation of cyclin D1 expression. Cancer Sci 2007; 98:629-635.
  • 28.
    Qie S, Diehl JA. Cyclin D1, cancer progression, and opportunities in cancer treatment. J Mol Med 2016; 94:1313-1326.
  • 29.
    Yeganeh M, Gui Y, Kandhi R, Bobbala D, Tobelaim WS, Saucier C. Suppressor of cytokine signaling 1-dependent regulation of the expression and oncogenic functions of p21(CIP1/WAF1) in the liver.Oncogene 2016; 35:4200-4211.
  • 30.
    Zhong M, Wu L, Wang J, Zhang B, Hou L. [Expression of cyclin D1 and its inhibitors and hTERT in ameloblastoma]. Hua Xi Kou Qiang Yi Xue Za Zhi 2006; 24:495-498.
  • 31.
    Kumamoto H, Kimi K, Ooya K. Detection of cell cycle-related factors in ameloblastomas. J Oral Pathol Med 2001; 30:309-315.
  • 32.
    Zamir-Nasta T, Razi M. Roles of p21, p53, cyclin D1, CDK-4, estrogen receptor alpha in aflatoxin B1-induced cytotoxicity in testicular tissue of mice. Environ Toxicol 2018; 33:385-395. ##.
comments

Leave a comment here

Share on
Metrics

Purchasing Reprints

  • Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here (   https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.
Search Relations

Author(s):

Related Articles