Abstract
Introduction: Psoriasis is a common chronic inflammatory skin disease. Cardiovascular diseases have been reported with greater frequency in patients with Psoriais. This may result from hyperlipidemia which seen in these patients. The aim of this study was to further study profiles of serum lipids and to determine, if any, correlation between severity of disease and extent of hyperlipidemia in these patients. Material and Methods: Subjects consisted of 52 patients with Psoriasis and 50 matched (sex and age) healthy persons as a control group. Blood samples were obtained following 14 hour fasting status and serum levels of triglyceride, cholesterol, HDL, LDL, VLDL were determined using standard laboratory methods. Results: Our findings showed that levels of TG, cholesterol, LDL and VLDL were significantly higher in psoriatic patients when compared with control ones (p< 0.001), but HDL level was similar between two groups. Also, any relationship was not found between lipids levels and severity of disease. Conclusion: Our findings further confirm lipid abnormalities in Psoriatic patients. This may enhance risk of cardiovascular diseases in these patients. Thus, we recommend all patients with Psoriasis, regardless of disease severity, should be checked for serum lipids profiles.
Keywords
: Psoriasis, hyperlipidemia, Cardiovascular disease پسوریازیس، بیماریهای کاردیوواسکولار، هایپرلیپیدمی
Copyright
© 2010, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.