Malnutrition-Inflammation Score in Hemodialysis Patients

Background: Malnutrition is a prevalent complication in patients on maintenance hemodialysis. Malnutrition-inflammation score (MIS), comprehensive nutritional assessment tool, as the reference standard was used to examine protein-energy wasting (PEW) and inflammation in hemodialysis patients.

Materials and Methods: In this descriptive- analytical study, 48 hemodialysis patients were selected with random sampling. All the patients were interviewed and the MIS of the patients was recorded. This new comprehensive Malnutrition-Inflammation Score (MIS) which involves 7 components from the SGA and the 3 additional non-SGA components of body mass index, serum albumin, and total iron-binding capacity (TIBC) has 10 components, each with four levels of severity, from 0 (normal) to 3 (very severe). These scores were compared with anthropometric measurements; laboratory measures. Data was analyzed with Chi-square and t-tests and Pearson correlation coefficiant.

Results: In this study 25% of patients on hemodialysis were normal nourished, 54.3% of patients were mild malnourished, 20.8% were moderately malnourished and no one of them were not sever malnurished. Pearson correlation coefficients between MIS score and age (r=+0.332) was significant. There was no correlation between the malnutrition score and sex Chi-square test showed significant correlation between MIS score and dialysis period ≥50 months (χ²=9.09)..

Conclusion: In this study, no one of patients has severed malnutrition, and most of them were assigned to the mildly/moderately malnourished rating. On other hand, most of patients are the well-nourished. Correlation between MIS score and age and dialysis period was significant.