Vitamin D and Hypertension

Tina Jafari Jafari; Zamzam  Paknahad

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

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Vitamin D and Hypertension

Author(s):

Tina Jafari Jafari¹,

Zamzam Paknahad^2,*

1Ph.D Student , Faculty of Nutrition and Food Sciences, Isfahan University of Medical Sciences,, Isfahan, Iran

2Department of Clinical Nutrition, Faculty of Nutrition and Food Sciences, Isfahan University of Medical Scienc, sfaha, Iran

Zahedan Journal of Research in Medical Sciences:Vol. 16, issue 6; 1-7

Published online:Jun 09, 2013

Article type:Review Article

Received:Sep 02, 2012

Accepted:Oct 03, 2012

How to Cite:Jafari T J, Paknahad Z. Vitamin D and Hypertension.Zahedan J Res Med Sci.2013;16(6):1-7.

Abstract

Nowadays, hypertension is one of the most important causes of death all over the world because of its adverse effects on cardiovascular system. For this reason its study is very valuable. Vitamin D is one of the important factors that may influence blood pressure. Many studies have shown the modulatory effect of this vitamin on rennin-angiotensin system as well as its inhibitory effect on vascular smooth muscle hypertrophy. According to the fact that vitamin receptors are distributed in almost all organs of human body, we can't consider its role just as factor in calcium homeostasis. Therefore many other important roles could be attributed to it. So vitamin D deficiency could arise many problems. There are many causes for vitamin D deficiency. The most important is insufficient exposure to UV-B. In epidemiological studies the vitamin D deficiency is considered to be associated with high blood pressure, as emphasized in many cross-sectional studies. Concerning the cohort prospective studies, the relationship between vitamin D deficiency and hypertension is reported in some cases. The interventional studies about the association between vitamin D and hypertension are not many and the results are different or contradictory. Controversial results might be due to differences in dose of supplements or duration of supplement therapy. The aim of this systematic review is to assess the researches about the association between vitamin D deficiency and hypertension and discuss the power of them. This can be helpful to lighten the path to prospective investigations.

Keywords

Vitamin D

Hypertension

Cardiovascular Diseases

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Author(s):

Tina Jafari Jafari:[PubMed][Scholar]
Zamzam Paknahad:[PubMed][Scholar]