The effects of cellular phone waves on the frequency micronucleus in newborn and adult Balb/C mouse

Javad  Baharara; Farhang Hadad; Mohammad A. Shariatzade; Maryam Amirahmadi

Zahedan Journal of Research in Medical Sciences

The Official Journal of Zahedan University of Medical Sciences

Current Issue All Issues In Press Articles Accepted Manuscripts Search

Journal Information Boards and Committees Indexing and Listing Sources Journal Metrics Open Peer Review (OPR)Publication Ethics and Malpractice Statement Contact Us Support Reviewer and AE Registration Form

APC

Authors Guide Submit Manuscript

The effects of cellular phone waves on the frequency micronucleus in newborn and adult Balb/C mouse

Author(s):

Javad Baharara^1,*,

Farhang Hadad²,

Mohammad A. Shariatzade³,

Maryam Amirahmadi⁴

1Associate Professor of Animal Developmental Biology, School of Basic Sciences, Islamic Azad University Mashhad Branch, Mashhad, Iran.

2Assistant Professor of Cell Genetics, School of Basic Sciences, Ferdowsi University, Mashhad, Iran.

3Professor of Histology& Embryology, School of Basic Sciences, Arak University, Arak, Iran.

4MSc of Cell& Developmental Biology, School of Basic Sciences, Islamic Azad University, Mashhad Branch, Mashhad Iran

Zahedan Journal of Research in Medical Sciences:Vol. 13, issue 4; e93932

Published online:May 27, 2011

Article type:Research Article

Received:Sep 13, 2010

Accepted:Sep 14, 2010

How to Cite:Javad BahararaFarhang HadadMohammad A. ShariatzadeMaryam AmirahmadiThe effects of cellular phone waves on the frequency micronucleus in newborn and adult Balb/C mouse.Zahedan J Res Med Sci.13(4):e93932.

Abstract

Background: In recent years, the widespread use of microwave producing instruments specially cell phones result in growing concern regarding the possible effects associated with these waves on human health especially pregnant woman and neonates. In present study, we investigated the genotoxic effects of cell phone radiation on the mice (Balb/C) and their offspring.

Materials and Method: In this experimental research, pregnant mice were irradiated with cell phone for 4 days of gestational age (days 14^th-18^th, 6h per day, from 9am until 3pm) and after litter, 2^nd-day offspring studied for morphology, weight and CR length. By following, for assessment of possible genetic damages in erythrocytes after bleeding from heart, smears of spleen tissue prepeard for histological studies. Mice peripheral blood and bone marrow smears prepared and stained with May-Granowald and Gimsa.

Results: The finding in experimental group indicated that cell phone radiation decreased offsprings’ weight and CR length (p<0.001). Megakaryocytes in marrow (p=0.02) and red blood cells in spleen (p=0.03) were increased but were not shown any changes in lymphocytes (p>0.05). An increase in micronucleus frequency in peripheral blood erythrocytes were seen in experimental newborn (p=0.006) and adult mice (p<0.001) but we did not found any change in the frequency of micronuclei in adult mice bone marrow polychromatic erythrocytes (p>0.05).

Conclusion: Above findings indicated that cell phone radiation (940 MHZ) are able to increase the frequency of micronucleus in peripheral blood erythrocytes of adult mice and their of fsprings and induce a genotoxic response.

Keywords

Fulltext

The full text of this article is available on the PDF file.

References

1.
The References of this article are available on the PDF file.

comments