Tuberculosis and drug resistance in Iran

Batool  Sharifi-Mood; Roya Alavi-Naini; Maliheh Metanat

Zahedan Journal of Research in Medical Sciences

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Tuberculosis and drug resistance in Iran

Author(s):

Batool Sharifi-Mood^1,*,

Roya Alavi-Naini¹,

Maliheh Metanat¹

1Associate Professor of Infectious disease, Research Center of Infectious disease and Tropical Medicine, Zahedan University of Medical Sciences and Health Services, Zahedan, Iran.

Zahedan Journal of Research in Medical Sciences:Vol. 12, issue 3; e94292

Published online:May 26, 2010

Article type:Review Article

Received:Jan 16, 2010

Accepted:Mar 10, 2010

How to Cite:Batool Sharifi-Mood, Roya Alavi-Naini, Maliheh Metanat, Tuberculosis and drug resistance in Iran.Zahedan J Res Med Sci.2010;12(3):e94292.

Abstract

Background : Tuberculosis is a great health issue in developing countries. Drug resistance is one of the principal problems in treating TB patients. In this review article we tried to demonstrate the prevalence of Multiple Drug Resistance (MDR), Extensively Drug Resistance (XDR) and Totally Drug Resistance (TDR) in tuberculosis patients in Iran.

Materials and Method : We used PUBMED, Scopus and scientific Iranian journals from the year 1970 to February 2010 for extracting data. Key words such as tuberculosis, drug resistance and Iran were used.

Results : There were several articles in this context but only articles in which Multiple Drug Resistance, Extensively Drug Resistance and Totally Drug Resistance tuberculosis were used were studied. The prevalence of MDR in several provinces of Iran was 0.5 to 27.9%. In Massih Daneshvari Hospital the prevalence of MDR and XDR were 5.4 and 10.6%, respectively.

Conclusion : The results of the study revealed that the rate of MDR is increasing in Iran. The appearance of XDR and TDR are serious threats in the control and treatment of tuberculosis.

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