Determination of Rifampin and Isoniazid resistant mycobacterium tuberculosis in Kermanshah (2006-2008)

Authors

Babak Izadi1, Malek Kanani1,*, Sedigheh Khazaei1, Sayed Hamid Madani1
1Dept. of Pathology. Molecular Pathology Research Center, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
*Corresponding Author: Corresponding author: Malek Kanani, Dept. of Pathology. Molecular Pathology Research Center, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran, Tel: +98 831 4283392 Email: [email protected]

Journal of Kermanshah University of Medical Sciences:Vol. 15, issue 2; e79383
Published online:Jul 19, 2011
Article type:Brief Report
Received:May 31, 2010
Accepted:Aug 03, 2010
How to Cite:Izadi B, Kanani M, Khazaei S, Madani SH. Determination of Rifampin and Isoniazid resistant mycobacterium tuberculosis in Kermanshah (2006-2008). J Kermanshah Univ Med Sci. 2011;15(2):e79383. doi:

Abstract

Tuberculosis is one of the most important infectious diseases and a major cause of morbidity and mortality in developing countries. Multi drug resistant tuberculosis is a new threat, which can result in a high case fatality rate. This study was conducted to define the incidence of multidrug resistant tuberculosis in Kermanshah. ­Antibiogram was performed on­­ PCR-confirmed isolates of mycobacterium tuberculosis by using the proportion method. Eight cases (57.1%) showed resistance to ­1µg/ml Isoniazid­. Resistance to Rifampicin was identified in 46.2% ­of cases.­ This study showed a high rate of single drug and multidrug resistance. We recommend antibiogram for all cases of tuberculosis.

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Copyright

© 2011, Journal of Kermanshah University of Medical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.

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