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78 resultsUpdated October 23, 2026
1

Ultrasound-Guided Nerve Hydrodissection for Pain Management: Rationale, Methods, Current Literature, and Theoretical Mechanisms

Journal of Pain Research Volume 13 (2020)

King Hei Stanley Lam; Chen‐Yu Hung; Yi‐Pin Chiang; Kentaro Onishi; Thomas B. Clark; Kenneth Dean Reeves; Su Daniel

3

Effectiveness of Conservative Treatment According to Severity and Systemic Disease in Carpal Tunnel Syndrome: A Systematic Review

International Journal of Environmental Research and Public Health 18(5) (2021)

Mar Hernández-Secorún; Raquel Montaña-Cortés; César Hidalgo-García; Jacobo Rodríguez‐Sanz; Jaime Corral-de-Toro; Sofía Monti-Ballano; Javier Sami Hamam-Alcober; José Miguel Tricás-Moreno; María Orosia Lucha-López

4

Volume Matters in Ultrasound-Guided Perineural Dextrose Injection for Carpal Tunnel Syndrome: A Randomized, Double-Blinded, Three-Arm Trial

Frontiers in Pharmacology 11 (2020)

Meng-Ting Lin; Chun-Li Liao; Ming‐Yen Hsiao; Hsueh‐Wen Hsueh; Chi‐Chao Chao; Chueh‐Hung Wu

5

Clinical Efficacy of Prolotherapy for Temporomandibular Joint Disorders: A Systematic Review and Meta-Analysis

Clinics and Practice 15(3) (2025)

Αντώνιος Σαραμάντος; Αthanassios Kyrgidis; Gregory Venetis; Georgios Hatziantoniou; Anestis Chrysostomidis; Chrysanthi Sardeli; Ioannis Tilaveridis

6

Treatment of Temporomandibular Dysfunction With Hypertonic Dextrose Injection (Prolotherapy): A Randomized Controlled Trial With Long-term Partial Crossover

Mayo Clinic Proceedings 94(5) (2019)

Wynand Francois Louw; Kenneth Dean Reeves; Stanley K.H. Lam; An-Lin Cheng; David Rabago

7

Effectiveness of Dextrose Prolotherapy for Rotator Cuff Tendinopathy: A Systematic Review

PM&R 12(3) (2019)

Michael S. Catapano; Kailia Zhang; Nimish Mittal; Harpreet Sangha; Kentaro Onishi; Darren L. de SA

8

Regenerative Medicine for Axial and Radicular Spine‐Related Pain: A Narrative Review

Pain Practice 20(4) (2019)

Mehul J. Desai; John Taylor Mansfield; David M. Robinson; Benjamin C. Miller; Joanne Borg‐Stein

9

Efficacy of hypertonic dextrose injection (prolotherapy) in temporomandibular joint dysfunction: a systematic review and meta-analysis

Scientific Reports 11(1) (2021)

Regina Wing Shan Sit; Kenneth Dean Reeves; Claire Chenwen Zhong; Charlene H. L. Wong; Bo Wang; Vincent CH Chung; Samuel Yeung Shan Wong; David Rabago

10

TRP channels in COVID-19 disease: Potential targets for prevention and treatment

Chemico-Biological Interactions 345 (2021)

Sahar Majdi Jaffal; Manal Ahmad Abbas

11

Prolotherapy for chronic low back pain: a review of literature

British Medical Bulletin 138(1) (2021)

Lorenzo Giordano; William Murrell; Nicola Maffulli

12

Regenerative medicine for the treatment of chronic low back pain: a narrative review

Journal of International Medical Research 51(2) (2023)

Fengfeng Wang; Chi Wai Cheung; Stanley Sau Ching Wong

13

The effectiveness of dextrose prolotherapy in plantar fasciitis

Medicine 100(51) (2021)

Wei-Fu Lai; Chang Ho Yoon; Meng‐Ting Chiang; Ying-Han Hong; Hui‐Chuan Chen; Wenyu Song; Yen Po Chin

14

Is 5% dextrose prolotherapy effective for radicular low back pain?

Gulhane Medical Journal 61(3) (2019)

Özlem Köroğlu; Aydan Örsçelik; Özlem Karasimav; Yasin Demir; İlker Solmaz

15

Subacromial corticosteroid injection versus subcutaneous 5% dextrose in patients with chronic rotator cuff tendinopathy: A short-term randomized clinical trial

Interventional Medicine and Applied Science 11(3) (2019)

Asadollah Amanollahi; Mahsa Asheghan; Seyed Ebrahim Hashemi

16

Is Low-Dose Dextrose Prolotherapy as Effective as High-Dose Dextrose Prolotherapy in the Treatment of Lateral Epicondylitis? A Double-Blind, Ultrasound Guided, Randomized Controlled Study

Archives of Physical Medicine and Rehabilitation 104(2) (2022)

Yıldız Gonca DOĞRU; Figen Tuncay; Fatmanur Aybala Koçak; Mehmet Okçu

17

Dextrose Prolotherapy for Symptomatic Grade IV Knee Osteoarthritis: A Pilot Study of Early and Longer-Term Analgesia and Pain-Specific Cytokine Concentrations

Clinics and Practice 12(6) (2022)

Gastón Andrés Topol; Ines Guerrero Pestalardo; Kenneth Dean Reeves; Fernando Elias; Neven J. Steinmetz; An‐Lin Cheng; David Rabago

18

The effect of dextrose prolotherapy versus placebo/other non‐surgical treatments on pain in chronic plantar fasciitis: a systematic review and meta‐analysis of clinical trials

Journal of Foot and Ankle Research 16(1) (2023)

Tannaz Ahadi; Masumeh Bagherzadeh Cham; Mahtab Mirmoghtadaei; Gholam Reza Raissi; Lobaneh Janbazi; Ghazal Zoghi

19

Modified prolotherapy by 5% dextrose: Two years experiences of a traditional and complementary medicine practice center in Turkey

Journal of Back and Musculoskeletal Rehabilitation 35(4) (2021)

İlker Solmaz; Aydan Örsçelik; Ozlem Koroglu

21

Treatment of Dorsal Back Pain with Glucopuncture

Medical Case reports and Reviews 4(1) (2021)

Jan Kersschot

22

Novel Sonoguided Digital Palpation and Ultrasound-Guided Hydrodissection of the Long Thoracic Nerve for Managing Serratus Anterior Muscle Pain Syndrome: A Case Report with Technical Details

Diagnostics 15(15) (2025)

Nunung Nugroho; King Hei Stanley Lam; Theodore Tandiono; Teinny Suryadi; Anwar Suhaimi; Wahida Ratnawati; Daniel Chiung‐Jui Su; Yonghyun Yoon; Kenneth Dean Reeves

24

Demonstrating the effectiveness of intra-articular prolotherapy combined with peri-articular perineural injection in knee osteoarthritis: a randomized controlled trial

Journal of Orthopaedic Surgery and Research 19(1) (2024)

Yiling Fu; Yukun Du; Jianyi Li; Yongming Xi; Wenbin Ji; Tieshan Li

25

Prolotherapy as a Regenerative Treatment in the Management of Chronic Low Back Pain: A Systematic Review

Medicina 61(9) (2025)

Stelian-Ilie Mociu; Andreea-Dalila Nedelcu; Andreea Alexandra Lupu; Andreea-Bianca Uzun; Dan Iliescu; Elena Valentina Ionescu; Mădălina Gabriela Iliescu

26

Dextrose injections for failed back surgery syndrome: a consecutive case series

European Spine Journal 28(7) (2019)

İlker Solmaz; Serkan Akpancar; Aydan Örsçelik; Özlem Karasimav; Deniz Gül

27

Is Epidural Injection of Sodium Chloride Solution a True Placebo or an Active Control Agent? A Systematic Review and Meta-Analysis

Pain Physician 1;24(1;1) (2020)

Laxmaiah Manchikanti; Nebojsa Nick Knezevic; Jaya Sanapati; Alan D Kaye; Mahendra R. Sanapati; Joshua Adam Hirsch

28

Prolotherapy for Musculoskeletal Pain and Disability in Low- and Middle-Income Countries

Physical Medicine and Rehabilitation Clinics of North America 30(4) (2019)

David Rabago; Kenneth Dean Reeves; Mary P. Doherty; Maelu Fleck

29

Prolotherapy: Potential for the Treatment of Chronic Wounds?

Advances in Wound Care 8(4) (2019)

Amir Hossein Siadat; R. Rivkah Isseroff

30

Periarticular hypertonic dextrose vs intraarticular hyaluronic acid injections: a comparison of two minimally invasive techniques in the treatment of symptomatic knee osteoarthritis

Open Access Rheumatology Research and Reviews Volume 11 (2019)

Behnam Hosseini; Mehrdad Taheri; Reza Pourroustaei Ardekani; Siamak Moradi; Morteza Kazempour Mofrad

32

Treatment of Sports Injuries with Glucopuncture

Archives in Biomedical Engineering & Biotechnology 5(1) (2021)

Jan Kersschot

33

Management of Lateral Elbow Pain with Glucopuncture

Global Journal of Orthopedics Research  3(1) (2021)

Jan Kersschot

38

Efficacy comparison between ultrasound-guided injections of 5% dextrose with corticosteroids in carpal tunnel syndrome patients

Neurological Research 45(6) (2023)

Aref Nasiri; Farzaneh Rezaei Motlagh; Mohammad Amin Vafaei

39

Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis: Feasibility, Acceptability, and Patient-Oriented Outcomes in a Pilot-Level Quality Improvement Project

The Journal of Alternative and Complementary Medicine 25(4) (2019)

David Rabago; Ina Kansariwala; David A.S. Marshall; Bobby Nourani; Mikel R. Stiffler-Joachim; Bryan C. Heiderscheit

40

Isotonic Glucose Injections for Postherpetic Neuralgia in the Elderly

Cureus 14(9) (2022)

Jan Kersschot; Ilan Karavani

42

A Novel Somatic Treatment for Post-traumatic Stress Disorder: A Case Report of Hydrodissection of the Cervical Plexus Using 5% Dextrose

Cureus 14(4) (2022)

Kenneth Dean Reeves; Jessica Shaw; Rebekah McAdam; King Hei Stanley Lam; Sean W. Mulvaney; David Rabago

44

Ultrasound-guided Gluco-puncture in the management of saphenous nerve entrapment in ultra-trail runner: A clinical case

World Journal of Advanced Research and Reviews 20(3) (2023)

Cyril Fischhoff; Kevin R. Vincent

45

Short-term efficacy of ultrasound-guided capsule-preserving hydrodilatation for primary frozen shoulder using 5% dextrose water vs. corticosteroid: a randomized controlled trial

Journal of Shoulder and Elbow Surgery 35(1) (2025)

Yao Liu; Yun‐Biao Hu; Miaomiao Xiong; Yuhang Kang; Jiayu Liu; Ming Fang; Ming Fang; Liping Chen

46

Comparison of Ultrasound-Guided Perineural 5% Dextrose Prolotherapy and Corticosteroid Injection in Mild to Moderate Carpal Tunnel Syndrome: A Retrospective Clinical Study

European Journal of Therapeutics 31(5) (2025)

Sevtap Badıl Güloğlu; Tuğba Şahbaz; Meral Bilgilisoy Filiz; Şebnem Koldaş Doğan; Hatice Kübra Aşık

47

POPÜLER BİR TAMAMLAYICI TIP TEDAVİSİ: PROLOTERAPİ

SDÜ Tıp Fakültesi Dergisi 30(1) (2022)

Aydan Örsçelik; İlker Solmaz

48

Dextrose concentration for prolotherapy: A study on human neuroblastoma cells

Gulhane Medical Journal 65(4) (2023)

Özlem Karasimav; Zehra Dilşad Çoban

49

The efficacy of ultrasound and fluoroscopy-guided caudal epidural prolotherapy versus steroids for chronic pain management in failed back surgery syndrome

Alexandria Journal of Medicine 60(1) (2024)

Yasmine Ragab Elsayed Mohamed; Ahmed Mohamed El-Attar; Dorreya Mohammed Fikry; Ahmed S. Shehab

51

Pain relief in a patient with snapping scapula after 5% dextrose injection

Turkish Journal of Physical Medicine and Rehabilitation 66(3) (2020)

Başak Mansız-Kaplan

52

Treatment of lateral ankle pain with glucopuncture: A clinical case

World Journal of Advanced Research and Reviews 19(1) (2023)

Ferrie J; Jan Kersschot

54

Treatment of Grade 1 Hamstring Injury with Glucopuncture: A Clinical Case

World Journal of Advanced Research and Reviews 19(3) (2023)

Jan Kersschot; D Laverde

55

History of Glucopuncture

World Journal of Advanced Research and Reviews 21(1) (2024)

Jan Kersschot

56

Ultrasound-guided Perineural Dextrose Injection for Treatment of Superior Cluneal Nerve Entrapment: Serial Case Report

The Open Pain Journal 14(1) (2021)

Yusak Mangara Tua Siahaan; Jessica Herlambang; Cynthia Putri; Pamela Tiffani

57

Ultrasound-Guided Nerve Hydrodissection for Pain Management: From Anatomy to Techniques

Springer eBooks (2022)

King Hei Stanley Lam; Yung‐Tsan Wu; Kenneth Dean Reeves

58

The Effect of Intra-articular Injection of Hypertonic Saline Versus Dextrose Prolotherapy for Knee Osteoarthritis

Annals of Military and Health Sciences Research 22(2) (2024)

Zahra Rezasoltani; Ensieh Taftian; Seyed Morteza Tabatabaee; Sharif Najafi; Sirous Azizi

59

Glucopuncture: Series of Regional Multiple Glucose 5% Injections

Advances in Complementary & Alternative Medicine 6(3) (2020)

Jan Kersschot

60

Glucopuncture for Traumatic Periostitis of the Tibial Crest. An Alternative for NSAIDs?

World Journal of Advanced Research and Reviews 15(3) (2022)

Mulder B and Kersschot J

61

Current Clinical Considerations in the Use of Dextrose Prolotherapy in Sport and Exercise Medicine

Acta Scientific Orthopaedics (2022)

Mark Wilson; Anna Topping; Stephan Praet

62

Dextrose prolotherapy for rotator cuff lesions: the challenges and the future

Hong Kong Medical Journal 24(5) (2018)

Regina Wing Shan Sit; David Rabago

63

Regenerative Medicine for the Spine

Springer eBooks (2020)

Anthony J. Mazzola; David A. Spinner

64

A RANDOMIZED CONTROL TRIAL ON EFFICACY OF ANALGESIC EFFECT OF 5% DEXTROSE CAUDAL EPIDURAL INJECTION FOR NON-SPECIFIC CHRONIC LOW BACK PAIN

INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH (2021)

Nitin Pandey; Priyanka Nayak; Vijendra Gahnolia

65

Dextrose Prolotherapy Injections for Chronic Non-Specific Low Back Pain

Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi 25(1) (2022)

Ekin İlke Şen; Mert Zure; Elham MALEKİFARD; Emel E. Ozcan

66

Glucopuntura para la Tendinopatía de Aquiles: una revisión descriptiva

South Florida Journal of Health 3(3) (2022)

A O'Byrne; Jan Kersschot

67

Isotonic glucose injections for anterior knee pain: A clinical case study

World Journal of Advanced Research and Reviews 15(1) (2022)

J Kersschot; J Borms

68

Glucopuncture for Achilles Tendinopathy: A Descriptive Review

World Journal of Advanced Research and Reviews 15(2) (2022)

A O'Byrne; Jan Kersschot

69

Dextrose Prolotherapy - Mechanism of Action

Acta Scientific Orthopaedics (2022)

Mark Wilson; Anna Topping; Stephan Praet

70

Glucopuncture: A novel injection therapy for non-specific low back pain

World Journal of Advanced Research and Reviews 16(3) (2022)

N Pandey; N Priyanka; G Vijendra; Jan Kersschot

72

Proposed Technique for Ultrasound-Guided Cervical Interlaminar Epidural Pharmacopuncture

Journal of Korean Medical Society of Acupotomology 9(2) (2025)

Jinsam Wang; Inhye Kang; Kyungho Kang

73

Comparison of Clinical Outcomes of 5% and 15% Dextrose Prolotherapy in Chronic Lateral Epicondylitis: A Retrospective Study

Acupuncture & Electro-Therapeutics Research (2026)

Sevtap Badıl Güloğlu; Tuğba Şahbaz; Meral Bilgilisoy Filiz; Şebnem Koldaş Doğan

74

Case Report: At Rare Case of Ulnar Sided Wrist Pain Secondary to Extensor Carpi Ulnaris Split Tear Respond Well to Prolotherapy

Malaysian Journal of Medicine and Health Sciences 21(2) (2025)

MA Aziz; Mohamed Nahar Azmi

75

Regenerative medicine of the spine

Elsevier eBooks (2026)

Newaj M. Abdullah; Usman Latif; Kelsey Gustafson; Dan T. Vu; Blake Evans; Tony K. George; Angel Boev

77

The Therapeutic Effect of Saline in Lumbar Injection Trials

JBJS Reviews 14(8) (2026)

Puru Sadh; Maxwell Dassow; Yousuf Suleman; M A Greenberg; Jinseong Kim; Bryce A. Basques

78

Ultrasound‐Guided Erector Spine Muscle Hydrodissection With 10% Dextrose for Treating Chronic Low Back Pain: A Retrospective Observational Study

Pain Practice 26(8) (2026)

Giorgio Pirrotta; Giuliano Lo Bianco; Bruno Giuseppe Gioia; Benedetta La Barbera; Giuseppe Natoli; Roberta Di Maggio; Alaa A Abd-Elsayed; Agnes Reka Stogicza; Michael E Schatman; Christopher Louis Robinson; Pasquale Enea