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Intraoperative ketamine administration to prevent delirium or postoperative cognitive dysfunction: A systematic review and meta‐analysis

Acta Anaesthesiologica Scandinavica 62(9) (2018)

Frédérique Hovaguimian; Chantal Tschopp; Beatrice Beck‐Schimmer; Milo Alan Puhan

Preventing postoperative cognitive dysfunction using anesthetic drugs in elderly patients undergoing noncardiac surgery: a systematic review and meta-analysis

International Journal of Surgery 109(1) (2023)

Kuan Zeng; Jingyi Long; Yi Li; Jichang Hu

2025 American Society of Anesthesiologists Practice Advisory for Perioperative Care of Older Adults Scheduled for Inpatient Surgery

Anesthesiology 142(1) (2024)

Frederick E. Sieber; Daniel I. McIsaac; Stacie G. Deiner; Tangwan B. Azefor; Miles Berger; Christopher G. Hughes; Jacqueline M. Leung; John Maldon; Julie Ryan McSwain; Mark D. Neuman; Marcia McGory Russell; Victoria Tang; Elizabeth L. Whitlock; Robert A. Whittington; Anne M. Marbella; Madhulika Agarkar; Stephanie Ramirez; Alexandre Dyer; Jaime Friel Blanck; Stacey Uhl; Mark D Grant; Karen B. Domino

Geriatric Pharmacology

Anesthesiology Clinics 37(3) (2019)

Tate M. Andres; Tracy Jobin McGrane; Matthew David McEvoy; Brian F.S. Allen

Effects of ketamine on postoperative cognition: a scoping review

British Journal of Anaesthesia 135(3) (2025)

Connor T. A. Brenna; Xuan He; Daheng Liu; Lilia Kaustov; Stephen Choi; Beverley Anne Orser

Anesthesia and cognitive disorders: a systematic review of the clinical evidence

Expert Review of Neurotherapeutics 16(11) (2016)

Federico Bilotta; Ega Qeva; Idit Matot

The effect of perioperative anesthetics for prevention of postoperative delirium on general anesthesia: A network meta-analysis

Journal of Clinical Anesthesia 59 (2019)

Yu Cui; Gen Li; Rong Cao; Liming Luan; Koffi M. Kla

Patients prone for postoperative delirium

Current Opinion in Anaesthesiology 29(3) (2016)

Ulf Guenther; Linda Riedel; Finn Michael Radtke

Evidence Review Conducted for the Agency for Healthcare Research and Quality Safety Program for Improving Surgical Care and Recovery: Focus on Anesthesiology for Total Hip Arthroplasty

Anesthesia & Analgesia 128(3) (2018)

Ellen M. Soffin; Melinda Maggard Gibbons; Clifford Y. Ko; Stephen L. Kates; Elizabeth Collens Wick; Maxime P. Cannesson; Michael J. Scott; Christopher L. Wu

Perioperative ketamine administration to prevent delirium and neurocognitive disorders after surgery: a systematic review and meta-analysis

International Journal of Surgery 109(11) (2023)

Souad Fellous; Baptiste Dubost; Amélie I. F. Cambriel; Marie‐Pierre Bonnet; Franck Verdonk

Effect of memantine on post-operative cognitive dysfunction after cardiac surgeries: a randomized clinical trial

DARU Journal of Pharmaceutical Sciences 25(1) (2017)

Saba Ghaffary; Padideh Ghaeli; Azita H. Talasaz; Abbasali Karimi; Maryam Noroozıan; Abbas Salehiomran; Arash Jalali

Effect of Ketamine on Postoperative Neurocognitive Disorders: A Systematic Review and Meta-Analysis

Journal of Clinical Medicine 12(13) (2023)

Dmitriy Viderman; Mina Aubakirova; Fatima Nabidollayeva; Nurgul Yegembayeva; Federico Bilotta; Rafael Badenes; Yerkin G. Abdildin

Tau protein plays a role in the mechanism of cognitive disorders induced by anesthetic drugs

Frontiers in Neuroscience 17 (2023)

Zheping Chen; Shenghan Wang; Zhaoqian Meng; Yuyang Ye; Guoliang Shan; Xinyue Wang; Xin Zhao; Yanwu Jin

Postoperative cognitive dysfunction in noncardiac surgery: A review

Trends in Anaesthesia and Critical Care 24 (2018)

Christopher M. Green; Susan D. Schaffer

Efficacy of intraoperative subanesthetic dose of ketamine/esketamine in preventing postoperative cognitive dysfunction: a systematic review and meta-analysis

Therapeutic Advances in Psychopharmacology 13 (2023)

Na Zhou; Chengchuan Chen; Yubei Liu; Zhaolan Yu; Yanhua Chen

Effects of anesthetic adjunctive agents on postoperative cognitive dysfunction in elderly patients undergoing noncardiac surgery: A Bayesian network meta‐analysis

Brain and Behavior 13(8) (2023)

Lichi Xu; Shuxiang Xu; Yuelun Zhang; Yuguang Huang

Patterns of prevention effectiveness in postoperative neurocognitive disorder and delayed neurocognitive recovery research: a systematic review with meta-regression of randomised trials

British Journal of Anaesthesia 135(2) (2025)

Niloy K. Lahiri; Nikola Vuckovic; Angad S. Sidhu; Jiangqiong Li; Yanhua Sun; Semanti Naiken; Samantha Curtis; Emma J. Bisch; Ryan Bolda; Prabhnoor S. Nagra; Gary Mann; Aiden E. Gonzales; Leah Smith; Brendan P. Anderson; Ziyue Liu; David C. Adams; Lingzhong Meng

Ketamine-induced Sustained Modulation of γ-Aminobutyric Acid Type A Receptor Function in Mouse Hippocampal Neurons after Anesthesia

Anesthesiology 143(4) (2025)

Dian-Shi Wang; Winston W. Li; Daheng Liu; Shahin Khodaei; Yalun Zhang; MeiFeng Yu; Howell Y. H. Fang; Agnes Crnic; Kirusanthy Kaneshwaran; Connor T. A. Brenna; Beverley Anne Orser

The impact of ketamine on cognitive outcomes in geriatric anesthesia: a comprehensive review

Frontiers in Psychiatry 16 (2025)

Shuyong You; Zhaohui Li

Ketamine: A Neuroanesthesiologist's Friend or Foe?

Journal of Neuroanaesthesiology and Critical Care 05(02) (2018)

Ankur Luthra; Girija P. Rath

Insulin resistance plays a potential role in postoperative cognitive dysfunction in patients following cardiac valve surgery

Brain Research 1657 (2017)

Ni Tang; Rongrong Jiang; Xiaobin Wang; Jian Wen; Li Liu; Jiali Wu; Chunxiang Zhang

Pharmacological Agents That Prevent Postoperative Cognitive Dysfunction in Patients With General Anesthesia: A Network Meta-analysis

American Journal of Therapeutics 28(4) (2020)

Mingguo Li; Yuanyuan Yang; Yanfang Ma; Qi Wang

A randomized controlled trial for measuring effects on cognitive functions of adding ketamine to propofol during sedation for colonoscopy

Medicine 99(36) (2020)

Liang Tian; Hengfei Luan; Pin Zhu; Zhiyuan Zhang; Hongguang Bao

The Effect of Opioid-Free Anesthesia with Esketamine on Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Thoracoscopic Surgery: A Prospective, Randomized, Controlled Trial

Drug Design Development and Therapy Volume 19 (2025)

Yuening Zhan; Zhaohui Liu; Song Meng; Mingze Luo; Zeqing Huang; Lingfei Wang

Subanesthetic Dose of Ketamine Administered Before Each Electroconvulsive Therapy Session Improves Antidepressant and Sleep Quality Outcomes

Journal of Ect 39(4) (2023)

Jun Dong; Su Min; Qibing Chen; Haitang Qiu; Li Ren

Role of Different Doses of Ketamine in Postoperative Neurocognitive Function in Aged Mice Undergoing Partial Hepatectomy by Regulating the Bmal1/NMDA/NF-Κb Axis

European Surgical Research 63(4) (2021)

Xiaoli Niu; Simin Zheng; Siyuan Li; Hongtao Liu

The effect of sedation methods on early postoperative cognitive decline in patients undergoing hip fracture surgery with spinal anesthesia: a prospective cohort study

BMC Surgery 26(1) (2026)

Ahmet Said Çetinkaya; Derya Arslan Yurtlu; Ahmet Salih Tüzen

Perioperative Cardiac Troponin I Levels in Patients Undergoing Total Hip and Total Knee Arthroplasty: A Single Center Study

Anesthesiology and Pain Medicine 8(6) (2018)

Mir Mohammad Taghi Mortazavi; Jafar Ganjpour Sales; Masoud Nouri‐Vaskeh; Masoud Parish; Salar Abdolhosseynzadeh

Study on the Effect of Dexmedetomidine on Postoperative Cognitive Dysfunction and Inflammation in Aged Rats

Contrast Media & Molecular Imaging 2022(1) (2022)

Ming‐Feng Hou; Qiongyu Zhang; Kai Deng

The impact of ketamine on delayed neurocognitive recovery in elderly patients undergoing spinal anaesthesia for orthopaedic procedures, a pilot study

Journal of Perioperative Practice 35(1-2) (2024)

Mostafa Samy Abbas; Mohamed Gamal Abo-Zeid; Fatma Gad-Elrab Askar; Omnia Ahmed Askar

Effect of ketamine/esketamine on postoperative delirium and cognitive dysfunctions: A systematic review and meta-analysis of randomised trials

Indian Journal of Anaesthesia 69(12) (2025)

Qianqian Guo; Xiaoyong Wei; Zhenghua Dong; Tao Wang; 博之吉留; Na Sun; Changsheng Li

The effects of dexmedetomidine on postoperative cognitive dysfunction in rats with bone fractures undergoing open reduction

American Journal of Translational Research 16(7) (2024)

Fuwang Yao

The effect of ketamine and oxytocin with pethidine in postoperative pain control in patients with laparoscopic cholecystectomy

International Journal of Surgery Open 63(5) (2025)

Arash Karimi; Mehrdad Amini; Seyede Hamideh Hashemiyazdi; Mozhgan Etemadian; Farshad Hassanzadeh Kiabi; Maryam Baghizadeh Baghdashti

Optimal prophylaxis for perioperative drug-induced delayed neurocognitive recovery: a Bayesian network meta-analysis of 18 interventions with mechanism-based stratification

Frontiers in Pharmacology 17 (2026)

Yaqing Liu; Yuqing Yao; X. T. Wang; Wenxue Fan; Xiuling Shang