Scopus by Title (Ref)

Acetaminophen inhibits diacylglycerol lipase synthesis of 2-arachidonoyl glycerol: Implications for nociception

Cell Reports Medicine

17 June 2025

Dvorakova M.

Open Access

The analgesic paracetamol metabolite AM404 acts peripherally to directly inhibit sodium channels

Proceedings of the National Academy of Sciences of the United States of America

10 June 2025

Maatuf Y.

Open Access

Pharmacokinetic profile of metabolites by heart-cutting two-dimensional liquid chromatography: A focus on paracetamol analysis

Journal of Chromatography A

29 March 2025

Ballester-Caudet A.

Open Access

Transcriptomic signature, bioactivity and safety of a non-hepatotoxic analgesic generating AM404 in the midbrain PAG region

Scientific Reports

December 2024

Bazan H.A.

Open Access

The Ocular Penetration and Intraocular Pressure Lowering Effect of Topical Acetaminophen in the New Zealand White Rabbit

Journal of Ocular Pharmacology and Therapeutics

1 October 2024

Anderson S.G.

High-Dose Acetaminophen as a Treatment for Cancer

Livers

March 2024

Wu J.

Open Access

Gestational paracetamol exposure induces core behaviors of neurodevelopmental disorders in infant rats and modifies response to a cannabinoid agonist in females

Neurotoxicology and Teratology

1 September 2023

Klein R.M.

Paracetamol and ibuprofen in the treatment of pain and fever in children: modern views on the choice of a drug

Meditsinskiy Sovet

2023

Zakharova I.N.

Open Access

Long-Term Paracetamol Treatment Impairs Cognitive Function and Brain-Derived Neurotrophic Factor in Adult Rat Brain

Scientia Pharmaceutica

2023

Lalert L.

Open Access

An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact

Journal of Pain Research

2023

Mallet C.

Open Access

Human sperm cells can form paracetamol metabolite AM404 that directly interferes with sperm calcium signalling and function through a CatSper-dependent mechanism

Human Reproduction

1 May 2022

Rehfeld A.

Teratogenic effects induced by paracetamol, ciprofloxacin, and their mixture on Danio rerio embryos: Oxidative stress implications

Science of the Total Environment

1 February 2022

Rosas-Ramírez J.R.

Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action

Temperature

2021

Ayoub S.S.

Open Access

Nonsteroidal anti-inflammatory drugs and acetaminophen ameliorate muscular mechanical hyperalgesia developed after lengthening contractions via cyclooxygenase-2 independent mechanisms in rats

Plos One

1 November 2019

Shimodaira T.

Open Access

A cannabinoid receptor type 1 (CB1R) agonist enhances the developmental neurotoxicity of acetaminophen (Paracetamol)

Toxicological Sciences

1 November 2018

Philippot G.

Open Access

Activation of the capsaicin-receptor TRPV1 by the acetaminophen metabolite N-arachidonoylaminophenol results in cytotoxicity

Life Sciences

1 February 2018

Stueber T.

AM404, paracetamol metabolite, prevents prostaglandin synthesis in activated microglia by inhibiting COX activity

Journal of Neuroinflammation

13 December 2017

Saliba S.W.

Open Access

First evidence of the conversion of paracetamol to AM404 in human cerebrospinal fluid

Journal of Pain Research

28 November 2017

Sharma C.V.

Open Access

Systems pharmacology of hepatic metabolism in zebrafish larvae

Drug Discovery Today Disease Models

4 February 2016

van Wijk R.C.

Open Access