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43 resultsUpdated October 23, 2026
1

Low‐dose Ketamine For Acute Pain Control in the Emergency Department: A Systematic Review and Meta‐analysis

Academic Emergency Medicine 28(4) (2020)

Nathan Balzer; Shelley L. McLeod; Chris Walsh; Keerat Grewal

2

Ketamine as Adjuvant for Acute Pain Management

Anesthesiology and Pain Medicine 9(6) (2019)

Farnad Imani; Giustino Varrassi

3

Comparative Effectiveness of Analgesics to Reduce Acute Pain in the Prehospital Setting

Prehospital Emergency Care 24(2) (2019)

Diana M Sobieraj; Brandon Keith Martinez; Benjamin Miao; Mark X. Cicero; Richard A. Kamin; Adrián Vladimir Hernández; Craig Ian Coleman; William L. Baker

4

Efficacy of analgesic and sub-dissociative dose ketamine for acute pain in the emergency department

The American Journal of Emergency Medicine 70 (2023)

Aeryana N. Beaudrie-Nunn; Erin D. Wieruszewski; Emily J Woods; Fernanda Bellolio; Kristin C. Mara; Elizabeth A. Canterbury

5

Low-dose ketamine versus morphine in the treatment of acute pain in the emergency department: A meta-analysis of 15 randomized controlled trials

The American Journal of Emergency Medicine 76 (2023)

Juan Guo; Fei Zhao; Jinglan Bian; Yunlong Hu; Jixiang Tan

8

Comparing the Effects of Low-Dose Ketamine, Fentanyl, and Morphine on Hemorrhagic Tolerance and Analgesia in Humans

Prehospital Emergency Care 27(5) (2023)

Joseph C. Watso; Mu Ryan Huang; Joseph M. Hendrix; Luke N. Belval; Gilbert Moralez; Matthew N. Cramer; Josh Foster; Carmen Hinojosa‐Laborde; Craig G. Crandall

9

Paramedic analgesia comparing ketamine and morphine in trauma (PACKMaN): a randomised, double-blind, phase 3 trial

The Lancet Regional Health - Europe 53 (2025)

Michael A. Smyth; Hannah Noordali; Kath Starr; Joyce Yeung; Ranjit Lall; Felix Michelet; Gordon Ward Fuller; Stavros Petrou; Alison Walker; Zoe Green; Rebecca McLaren; Elisha Miller; Duncan Buckley; Gavin D. Perkins

10

Continued Opioid Use and Adverse Events Following Provision of Opioids for Musculoskeletal Pain in the Emergency Department: A Systematic Review and Meta-Analysis

Drugs 83(16) (2023)

Qiuzhe Chen; Christopher Gerard Maher; Christopher Sejong Han; Christina Abdel Shaheed; Chung‐Wei Christine Lin; Eileen M. Rogan; Gustavo C Machado

11

Randomised controlled trial of analgesia for the management of acute severe pain from traumatic injury: study protocol for the paramedic analgesia comparing ketamine and morphine in trauma (PACKMaN)

Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 31(1) (2023)

Felix Michelet; Michael A. Smyth; Ranjit Lall; Hannah Noordali; Kath Starr; L. Berridge; Joyce Yeung; Gordon Ward Fuller; Stavros Petrou; A. Walker; J. Mark; Alastair Canaway; Khalid Saeed Khan; Gavin D. Perkins

12

A randomized, noninferiority, controlled trial of two doses of intravenous subdissociative ketamine for analgesia in the emergency department

Academic Emergency Medicine 28(6) (2020)

Shannon Lovett; Trent Reed; Robert Riggs; George Lew; Erica Koch; Ramón Durazo-Arvizú; Megan A. Rech

13

Low-dose morphine reduces tolerance to central hypovolemia in healthy adults without affecting muscle sympathetic outflow

American Journal of Physiology-Heart and Circulatory Physiology 323(1) (2022)

Joseph C. Watso; Luke N. Belval; Frank A. Cimino; Bonnie D. Orth; Joseph M. Hendrix; Mu Ryan Huang; Elias Johnson; Josh Foster; Carmen Hinojosa‐Laborde; Craig G. Crandall

14

Effectiveness of Opioid Analgesic Medicines Prescribed in or at Discharge From Emergency Departments for Musculoskeletal Pain

Annals of Internal Medicine 175(11) (2022)

Caitlin M. P. Jones; Chung‐Wei Christine Lin; Masoud Jamshidi; Christina Abdel Shaheed; Christopher Gerard Maher; Ian Andrew Harris; Asad E. Patanwala; Michael Minh Quoc Dinh; Stephanie Mathieson

15

Comparison of the efficacy of intranasal ketamine versus intravenous ketorolac on acute non-traumatic headaches: a randomized double-blind clinical trial

Head & Face Medicine 18(1) (2022)

Hooman Rafiei; Hamidreza Baigrezaii; Mohammad Nazarianpirdosti; Amirhossein Meysami; Roya Safari‐Faramani

16

Low-dose morphine reduces pain perception and blood pressure, but not muscle sympathetic outflow, responses during the cold pressor test

American Journal of Physiology-Heart and Circulatory Physiology 323(1) (2022)

Joseph C. Watso; Luke N. Belval; Frank A. Cimino; Bonnie D. Orth; Joseph M. Hendrix; Mu Ryan Huang; Elias Johnson; Josh Foster; Carmen Hinojosa‐Laborde; Craig G. Crandall

18

Adverse Effects Associated With High-Dose Ketamine Infusions For Refractory Pain And Psychiatric Conditions

Current Pain and Headache Reports 29(1) (2025)

Elika D. Javaheri; Christopher S. Wie; Stephen M. Covington; Lopa Misra; Scott Pew; Omar Viswanath; John Freeman; Jillian A. Maloney

19

Melatonin Blocks Morphine-Induced Place Preference: Involvement of GLT-1, NF-κB, BDNF, and CREB in the Nucleus Accumbens

Frontiers in Behavioral Neuroscience 15 (2021)

Badrah Saeed Ali Alghamdi; Fahad S. Alshehri

20

Low-Dose Ketamine Infusion Versus Morphine Infusion During Abdominoplasty to Change the Postoperative Pain Profile

Anesthesiology and Pain Medicine 10(6) (2020)

Hassan Mohamed Ali; Ahmed Abdelaziz Ismail; Amr Samir Wahdan

21

The Effectiveness of Ketamine Versus Opioids in Patients With Acute Pain in the Emergency Department: A Systematic Review and Meta-Analysis

Cureus 15(3) (2023)

Bsaim Abdulsalam Altirkistani; Alaa Adel Ashqar; Dena M. Bahathiq; Suaad Bougis; Ammar Aljabri; Sawsan Hanafi

22

A Comparison of Tertiary Drug Resources’ Consistency Regarding Drug-Drug Interactions of Adjunctive Analgesics

Journal of Pharmacy Technology 37(1) (2020)

Andrew Lang; Michael A. Veronin; Justin P. Reinert

23

Ketamine in the Management of Acute Pain: A Comprehensive Meta-Analysis

Journal of College of Physicians And Surgeons Pakistan 34(01) (2024)

Xinhua Shi; Juan Zhou; He Jiang; Keqi Xie

24

Muscone reduced the hypnotic and analgesic effect of ketamine in mice

Journal of the Chinese Medical Association 83(2) (2020)

Chuiliang Liu; Zeqi Huang; Zhipeng Li; Junhua Li; Yujuan Li

25

Effectiveness of pain management among trauma patients in the emergency department, a systematic review

International Emergency Nursing 62 (2022)

Hana Mohammad Abu‐Snieneh; Abdalkarem F. Alsharari; Fuad Hamdi A. Abuadas; Mohammed Alqahtani

27

Low-dose ketamine as an analgesic agent in the emergency department: Efficacy and safety

Journal of Family Medicine and Primary Care 11(10) (2022)

Ramin Parvizrad; Somayeh Nikfar

28

How to deal with pain in the emergency department - pain management review

Journal of Education Health and Sport 51 (2024)

Katarzyna Beutler; Bartosz Bijata; Dawid Burek; Aleksandra Paszkowska; Aleksandra Kujawa; Urszula Matuszewska; Aleksandra Nykowska

30

Unlocking the Potential of Ketamine: A Systematic Review and Meta-analysis of its Safety and Efficacy in Acute Pain Management

Combinatorial Chemistry & High Throughput Screening 28(18) (2025)

Xiaojuan Chou; Wenhua Zha; Jian Hu; Chen Chen; Rajesh K. Singh; Geng Liu

31

Interactions between Ketamine and Magnesium for the Treatment of Pain: Current State of the Art

CNS & Neurological Disorders - Drug Targets 20(5) (2021)

Katarina Savić Vujović; Sonja Maksim Vuckovic; Radan Stojanović; Nevena Divac; Branislava Medić; Aleksandar Vujović; Dragana Srebro; Milica S. Prostran

32

Comparing the efficacy of nebulized morphine with intravenous morphine in traumatic musculoskeletal pain management

Journal of Research in Clinical Medicine 8(1) (2020)

Mani Mofìdi; Ali Dashti; Mahdi Rezai; Niloufar Ghodrati; Hoorolnesa Ameli; Hassan Amırı

33

Low Dose Ketamine Used for Acute Pain Management in the Emergency Department

Open Journal of Emergency Medicine 08(01) (2020)

Catherine Kestenian; Raymund Gantioque; Eric Snyder

34

Retrospective Examination of Pain Relief Approaches According to Trauma Severity in Emergency Trauma Units

Journal of Academic Research in Nursing (2020)

Züleyha Karadaş; Emel Bahadır Yılmaz

35

Is Low-Dose Ketamine an Effective Alternative to Opioids for Acute Pain?

Annals of Emergency Medicine 73(5) (2018)

Jonathan M. Kirschner; Benton R. Hunter

36

Comparative safety and efficacy of low dose ketamine and opioids for acute pain management at the emergency department

INTERNATIONAL JOURNAL OF ENDORSING HEALTH SCIENCE RESEARCH (IJEHSR) 7(4) (2019)

Syed Jehanzeb Asim; Muhammad Aqil; Wajahat Ali; Lal Shehbaz; Shua Nasir

37

Opioid-free analgesia in the emergency department: A new aspect

Journal of Research in Clinical Medicine 8(1) (2020)

Hassan Soleimanpour

39

The Role of Ketamine in Trauma

IntechOpen eBooks (2022)

Mihai Octavian Botea; Erika Bimbó-Szuhai

40

Bridging the gap: Addressing critiques of the efficacy of analgesic and sub-dissociative dose ketamine for acute pain in the emergency department

The American Journal of Emergency Medicine 87 (2024)

Aeryana N. Beaudrie-Nunn; Erin D. Wieruszewski; Fernanda Bellolio; Elizabeth A. Canterbury

41

Ketamine versus Morphine for Musculoskeletal Trauma Pain: A Meta-analysis of Randomized Controlled Trials

European Journal of Orthopaedic Surgery & Traumatology 36(1) (2026)

Mansoureh Fatahi; Alireza Ebrahimi; Saba Aghajani; Melika Arab Bafrani; Reham H Hamouda; Masoud Mayel

42

Ketamine for acute and chronic pain: beyond anaesthesia

Pain Management 16(5) (2026)

Hao G. Duong; Tariq G. Pulskamp; Daniel J. Berlau