Evaluation of relationship between serum cholesterol and triglyceride level and gallstone incidence

Background: Cholecystectomy is one of the most common operations in the field of general surgery. It has higher cost in operations with complication and in these cases mortality and morbidity will increase. The main goal of this research is the study and compare of cholesterol and triglyceride serum level in gallstone group and control group. Materials and Methods: The role of Serum total cholesterol and triglyceride level in the etiology of gallstone disease was assessed in a case control study in Emam Reza hospital. Study include 37 cases (15 males and 22 females) with surgically or ultrasonographicaly confirmed cholecystolithiasis and 35 cases (16 males and 19 females) as control outpatient and hospital admitted patient without debilitating disease (such as umbilical and inguinal Hernia) over age of forty. Mean age in stone group was 54 years and in control group was 57 years. Results: Serum cholesterol and triglyceride concentration in gallstone patient was 193 mg/dl and 135.9 mg/dl respectively were compared with control series with cholesterol and triglyceride levels 176 mg/dl and 121.8 mg/dl respectively (p=0.258 for cholesterol &p=0.368 for triglyceride). Conclusion: Gallstone patient had higher serum cholesterol and triglyceride level than control group but these differences were not statistically significant.