Archives of Clinical Infectious Diseases
In spite of many advantages of modern medicine in comparison with traditional treatments, chemical therapeutic agents have side effects. Pistachio skin extract has antibacterial effects, but side effect has not been reported
The aim of this study was to compare the effects of pistachio skin extract with that of antibiotics such as amoxicillin, tetracycline, cefixime and ciprofloxacin, on enteric bacteria collected from patients with gastroenteritis.
Experimental method was used for this study. One hundred samples were taken from patients with gastroenteritis; then, the samples were characterized and the diagnosis was made. The pistachios internal soft skin extracts were obtained, using the decoction method and water as the solvent. Afterwards, the solution was crystallized and placed on 37C and its water has been evaporated. The solution required two days for the entire water loss process. Antibacterial effect of the extract was analyzed with the disc diffusion method using Mueller-Hinton agar medium. After steeping the blank disc in the extract, bacteria reached 0.5 McFarland density, were cultured on plates with four antibiotic discs including amoxicillin, tetracycline, cefixime and ciprofloxacin. Next, depending on the type of bacteria, the inhibition zones were compared to determine the antibiotic inhibitory effects. Statistical analysis for comparing the antibiotics and pistachio skin extract effects was performed using chi-square tests.
Regarding the natural therapeutic effects of pistachio skin extract and obligations of the routine antibiotics such as resistancy, using pistachio extract as a co-therapeutical agent with ordinary antibiotics can enhance the success rate of the treatment.
© 2014, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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