Logo
homeHome
toggle_offCompany ProfilegroupsBoards & Staffsworkspace_premiumMemberships & PartnersschoolAcademy of Journalismperson_addCareerslinkBlog(EN)emailContact Us
list_altOur JournalslightbulbInstruction for AuthorsbookmarkBrieflands PolicieshandshakePublish My Researchplay_circleJournal Management Systemcredit_cardArticle Processing Chargeszoom_inOpen Peer ReviewimagePublishing Services
menu_bookPublish My Book

Archives of Clinical Infectious Diseases

Infectious Diseases and Tropical Medicine Research Center, SBUMS

homeHome
play_arrowCurrent Issuecheck_circleAccepted ManuscriptslistAll Issuesformat_indent_increaseIn PresssearchSearch
settingsInstructions
bookmarkJournal InformationgroupsEditors & BoardsshareIndexing and Listing Sourcesshow_chartJournal MetricsbalancePublication Ethics and Malpractice StatementemailSupportphoneContact Usassignment_indReviewer and AE Registration Formzoom_inOpen Peer Review (OPR)
format_list_bulletedAPC
Authors GuideSubmit Manuscript

Outlines

Serum Antithrombin III Level in Multi-Trauma Patients Who Develop Sepsis

Author(s):
Parviz SalehParviz Saleh1, Hamid NoshadHamid Noshad2,*, Firooz SalehpourFirooz Salehpour3
1Assistant Professor of Infectious Diseases, Tabriz University of Medical Sciences, Tabriz, IR Iran
2Chronic Kidney Disease Research Center, Tabriz University of Medical Sciences, Tabriz, IR Iran.
3Professor of Neurosurgery, Tabriz University of Medical Sciences, Tabriz, IR Iran
Archives of Clinical Infectious Diseases:Vol. 7, issue 1; 25-8
Published online:Jan 31, 2012
Article type:Research Article
How to Cite:Saleh P, Noshad H, Salehpour F. Serum Antithrombin III Level in Multi-Trauma Patients Who Develop Sepsis. Arch Clin Infect Dis. 2012;7(1):. doi:

Abstract

Methods:

From January 2010 to June 2010, 50 patients with multi-trauma injuries were enrolled in our study. All of them were hospitalized in the intensive care unit (ICU) of neurosurgery department, Imam Reza university hospital, Tabriz University of Medical Sciences, Tabriz, Iran. Twenty-four patients demonstrated sepsis manifestations (sepsis group), but 26 patients did not (non-sepsis group). During ICU stay, blood levels of AT III were measured on days 0, 3, 7. Then, the obtained values were compared between the two groups.

Results:

Mean (standard deviation, SD) serum AT III level upon hospitalization was 95.00 (15.55) g/ml in sepsis group and 106.28 (17.45) g/ml in non-sepsis group (P= 0.02). Serum AT III level variations during an inter-group study was not significant in non-sepsis group (P= 0.74), but it was statistically significant in sepsis group (P< 0.001). Serum AT III level variations were studied in patients with and without sepsis at different time points with repeated measured ANOVA test. This analysis showed that the variations were statically significant in both groups (P< 0.001).

Conclusion:

Serum AT III level was lower in trauma patients who developed sepsis. Inter-group study showed that serum AT III level variations were statistically significant in the sepsis group but not in the non sepsis patients. So AT III serum level measurement may predict the occurrence of sepsis in traumatic patients earlier.

Full Text

Full text is available in PDF
Import into EndNoteImport into BibTex
Share on
Comments
Number of Comments:0
Cited by
Metrics

Purchasing Reprints

  • Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here (   https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.
Search Relations

Author(s):

Related Articles

Related Article in PubMed

Related Article in Google Scholar

Create Citation Alert via Google Reader