Logo
homeHome
toggle_offCompany ProfilegroupsBoards & Staffsworkspace_premiumMemberships & PartnersschoolAcademy of Journalismperson_addCareerslinkBlog(EN)emailContact Us
list_altOur JournalslightbulbInstruction for AuthorsbookmarkBrieflands PolicieshandshakePublish My Researchplay_circleJournal Management Systemcredit_cardArticle Processing Chargeszoom_inOpen Peer ReviewimagePublishing Services
menu_bookPublish My Book

Archives of Clinical Infectious Diseases

Infectious Diseases and Tropical Medicine Research Center, SBUMS

homeHome
play_arrowCurrent Issuecheck_circleAccepted ManuscriptslistAll Issuesformat_indent_increaseIn PresssearchSearch
settingsInstructions
bookmarkJournal InformationgroupsEditors & BoardsshareIndexing and Listing Sourcesshow_chartJournal MetricsbalancePublication Ethics and Malpractice StatementemailSupportphoneContact Usassignment_indReviewer and AE Registration Formzoom_inOpen Peer Review (OPR)
format_list_bulletedAPC
Authors GuideSubmit Manuscript

Outlines

Tuberculous, Pyogenic, and Brucellar Vertebral Osteomyelitis: A 10-year Experience

Author(s):
Mahshid Talebi TaherMahshid Talebi Taher1,*, Fatemeh ShiraniFatemeh Shirani2, Jafar Jabari lakJafar Jabari lak3, Mitra BaratiMitra Barati4
1Antimicrobial Resistance Research Center, Infectious Disease Department, Rasouleakram Hospital, Tehran University of Medical Sciences,Tehran, IR Iran
2Rheumatologist, Internal Medicine Department, Rasouleakram Hospital, Tehran University of Medical Sciences, Tehran, IR Iran
3Internist, Rasouleakram Hospital, Tehran University of Medical Sciences, Tehran, IR Iran
4Pediatric Infectious Diseases Research Center, Infectious Disease Department, Rasouleakram Hospital, Tehran University of Medical Sciences, Tehran, IR Iran
Archives of Clinical Infectious Diseases:Vol. 7, issue 1; 17-20
Published online:Jan 31, 2012
Article type:Research Article
How to Cite:Talebi Taher M, Shirani F, Jabari lak J, Barati M. Tuberculous, Pyogenic, and Brucellar Vertebral Osteomyelitis: A 10-year Experience. Arch Clin Infect Dis. 2012;7(1):. doi:

Abstract

Patients and Methods:

In this descriptive-comparative study, all patients older than 1 year who were hospitalized at Rasoul-e-Akram Hospital from 1999 to 2009 with a confirmed diagnosis of VO were included. The diagnosis of VO was confirmed in the presence of compatible clinical features, vertebral CT scan or MRI. Etiological diagnosis of VO was defined when the microorganism was isolated from blood culture, bone biopsy, paravertebral abscess aspiration; typical histopathological pattern of tuberculosis (caseating granuloma) or malignancy in bone biopsy; Wrights or serum agglutination test 1/80 or 2ME 1/40 according to the national guidelines. Analytical statistics such as the chi-square and t test were used to find correlation and relationships among the variables. P< 0.05 was considered to indicate statistical significance.

Results:

A total number of 87 patients studied. There were 62 (71.26%) males and 25 (28.73%) females. Thirty-eight (43.67%) patients had PVO, 26 (29.88%) had TVO, 18 (20.68%) had BVO, 3 (3.4%) had malignant disorder with metastasis to bone, and the remaining 2 (2.29%) cases had fungal VO. Fever and back pain were the most common symptoms in PVO (12), but in TVO the most common symptom was back pain. DM and previous bone spinal surgery were the most common underlying diseases in PVO patients (P=0.000). Paravertebral abscess was reported in 6 (23.7%) patients with TVO and 6 patients (15.78%) with PVO, but no such complication was noted in BVO group.

Conclusion:

There are significant differences between VO by different microorganisms that help physician to start empirical medical treatment while waiting to definite diagnosis by blood culture, culture from paravertebral abscess, serology and bone biopsy.

Keywords
Vertebral osteomyelitis
pyogenic osteomyelitis
brucella osteomyelitis
tuberculous osteomyelitis

Full Text

Full text is available in PDF
Import into EndNoteImport into BibTex
Share on
Comments
Number of Comments:0
Cited by
Metrics

Purchasing Reprints

  • Copyright Clearance Center (CCC) handles bulk orders for article reprints for Brieflands. To place an order for reprints, please click here (   https://www.copyright.com/landing/reprintsinquiryform/ ). Clicking this link will bring you to a CCC request form where you can provide the details of your order. Once complete, please click the ‘Submit Request’ button and CCC’s Reprints Services team will generate a quote for your review.
Search Relations

Author(s):

Related Articles

Related Article in PubMed

Related Article in Google Scholar

Create Citation Alert via Google Reader