Archives of Clinical Infectious Diseases
Haleh Talaie1,*, 
Sepideh Kamalbeik3, Arezou Mahdavinejad1, Abdolkarim Pajoumand2, Seyed Ali Bahreini Moghaddam4One of the prominent microorganisms in several reports of nosocomial infections is Staphylococcus aureus (S. aureus) which is carried by several health care workers (HCW) many times throughout the day. The present investigation was conducted to assess the nasal and hand carriage rate of S. aureus amongst medical personnel of Loghman Hakim Hospital's Toxicological Intensive Care Unit (TICU).
All health care workers of TICU (n= 70) were recruited to this study. A questionnaire with demographic information, work category, duration of working in the (TICU) and history of infection by S. aureus was completed by one trained nurse of the ward. A total of 140 swabs (nasal=70, hand=70) were collected from personnel in TICU. Isolates with both inhibition zone diameter ?13 mm around oxacillin disc and ?21 mm around cefoxitin disc were considered MRSA strains. Also, we used KOH preparation technique to identify hyphae from the samples.
Eighteen (25.7%) persons were S. aureus carriers while methicillin-resistant staphylococcus aureus (MRSA) was found in 6 (8.6%) subjects. There was no significant difference between the sexes (p = 0.075), age (p = 0.080), work category (p=0.100), and duration of working in the TICU (?5 and>5 years) (p = 0.875) with regard to nasal and hand carriage of S. aureus.
Transmission of S. aureus by HCWs has to be concerned, however more studies are required to examine the relationship between nasal or hand colonization of MRSA in HCWs and subsequent MRSA infection in patients.
© 2011, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
Bijari A, Hallaj Zade M, Hatami S, Kalantar E, Noori Sepehr M, et al. High Frequency of Methicillin-Resistant Staphylococcus aureus in Intensive Care Unit in Karaj, Iran. Arch Clin Infect Dis. 2018;13(5):e61917. doi: https://doi.org/10.5812/archcid.61917
Moazen J, Riyahi Zaniani F, Raje R. Characterization of Staphylococcus aureus Nasal Carriage Among Healthcare Providers in an Intensive Care Unit: Insights into Antibiotic Resistance Profiles and Virulence Gene Distribution. Arch Clin Infect Dis. 2023;18(6):e137545. doi: https://doi.org/10.5812/archcid-137545
Nazemsadati S, Allami A, Hajmanoochehri F. Staphylococcus aureus colonization in Qazvin University hospitals healthcare workers. J Inflamm Dis. 2024;22(2):e156078. doi:
Rashidi Nezhad R, Meybodi SM, Rezaee R, Goudarzi M, Fazeli M. Molecular Characterization and Resistance Profile of Methicillin Resistant Staphylococcus aureus Strains Isolated from Hospitalized Patients in Intensive Care Unit, Tehran-Iran. Jundishapur J Microbiol. 2017;10(3):e41666. doi: https://doi.org/10.5812/jjm.41666
Moazen J, Riyahi Zaniani F, Hallaj Asghar B. Characterization of Virulence Genes and Antibiotic Resistance of Methicillin-resistant Staphylococcus aureus (MRSA) and Methicillin-susceptible Staphylococcus aureus (MSSA) Isolates in Intensive Care Unit (ICU) and Non-ICU Wards. J Adv Immunopharmacol. 2022;2(2):e129037. doi: https://doi.org/10.5812/tms-129037
Last Update: 2 weeks ago
Last Update: 2 weeks ago
Last Update: 2 weeks ago
Last Update: 5 days ago
Ordering Reprints
Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC
Author(s):
