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Official Journal of Research Center for Gastroenterology and Liver Diseases
e-ISSN 1735-3408
p-ISSN 1735-143X
Milk thistle for treatment of nonalcoholic fatty liver disease
Authors
1Department of Experimental and Clinical Medicine, University of Magna Grcia, l.abenavoli@unicz.it, Italy
2Department of Experimental Pharmacology, University of Federico, Italy
3Department of Pharmacy, University of Novi Sad, Serbia
*Corresponding Author: Department of Experimental and Clinical Medicine, University of Magna Grcia, l.abenavoli@unicz.it, Italy. Tel: +39-9613697113. Fax: +39-961754220. Email: l.abenavoli@unicz.it
Published online:Mar 31, 2011
Article type:Review Article
Received:Sep 25, 2010
Accepted:Jan 17, 2011
How to Cite:Abenavoli L, Aviello G, Capasso R, Milic N, Capasso F. Milk thistle for treatment of nonalcoholic fatty liver disease. Hepat Mon. 2011;11(3):. doi:
Abstract
Nonalcoholic fatty liver disease (NAFLD) is one the most common causes of chronic liver disorders in the Western world. These patients have many significant comorbidities. The therapeutic approach to NAFLD is based on lifestyle intervention, but there is no consensus on the ideal pharmacological treatment. Silybum marianum, commonly known as milk thistle (MT), is one of the oldest and most extensively researched plants in the treatment of liver diseases. Many studies have demonstrated that the active components of MT silymarin have many hepatoprotective properties. In recent years, several preclinical and clinical reports have described the efficacy of silymarin as a treatment for NAFLD. The chief aim of this review is to discuss the newest and most promising applications of MT in the treatment of NAFLD.
Implication for health policy/practice/research/medical education:
This article describes the importance of natural treatment regimen like plant extracts in treating NAFLD and can be attended by general practitioners and family physicians and others who are involved in treating patients with liver disorders.
Please cite this paper as:
Abenavoli L, Aviello G, Capasso R, Milic N, Capasso F. Milk thistle for treatment of nonalcoholic fatty liver disease. Hepat Mon. 2011;11(3):173-177.
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Copyright
© 2011, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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