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Official Journal of Research Center for Gastroenterology and Liver Diseases
e-ISSN 1735-3408
p-ISSN 1735-143X
Seroprevalence of Hepatitis Viruses B, C, D and HIV Infection Among Hemodialysis Patients in Kerman Province, South-East Iran
Authors
1The Liver-Biliary-Pancreatic Center, Cannon Research Center, Carolinas Medical Center, Charlotte, USA
2Department of Biology, University of North Carolina at Charlotte, Charlotte, USA
*Corresponding Author: Hossein Sendi. Liver-Biliary-Pancreatic Center, Cannon Research Center, Carolinas Medical Center, Charlotte, NC 28203, USA. Tel: +1-7043557226, Fax: +1-7043551980, E-mail: [email protected], [email protected] Email: [email protected]
Published online:May 31, 2012
Article type:Research Article
Received:Apr 01, 2012
Accepted:Apr 25, 2012
How to Cite:Sendi H. Seroprevalence of Hepatitis Viruses B, C, D and HIV Infection Among Hemodialysis Patients in Kerman Province, South-East Iran. Hepat Mon. 2012;12(5):. doi: https://doi.org/10.5812/hepatmon.6128
Abstract
Background: The prevalence of hepatitis viruses in hemodialysis patients has been reported to be much greater than in the general population. Attention to local data, effectively guides health planners so that they can control infections and prevent nosocomial transmissions.
Objectives: This cross sectional study was carried out to determine the prevalence of hepatitis B (HBV), hepatitis C (HCV), and hepatitis D (HDV) viruses, as well as the human immunode?ciency virus (HIV) in dialysis centers in the Kerman Province, in the southeast of Iran.
Patients and Methods: All hemodialysis patients (n = 228) in 7 centers were enrolled in the study. Hepatitis B surface antigens (HBsAg), HCV antibodies (Ab), HDV Ab and HIV Ab were measured using speci?c enzyme linked immunoassay kits (ULTRA kit, bioMérieux, France) and con?rmed by a qualitative PCR assay.
Results: The studied group was comprised of 92 (40.4%) females and 136 (59.6%) males. The mean age of the patients was 51 ± 9.5 years and the duration of hemodialysis was 39.7 ± 7.9 months. Positive HBsAg was found in 7% of cases, HCV Ab in 7%, and patients with both viruses were detected in 1.7% cases. HIV Ab and HDV Ab were negative in all cases. Out of the other risk factors, frequency of blood transfusions was signi?cantly correlated with positive HCV Ab (P < 0.008).
Conclusions: Prevalence of HBV and HCV in hemodialysis patients was moderate to low in the Kerman Province, as in other parts of the country. Strict adherence to protective measures could lead to even lower rates.
Implication for health policy/practice/research/medical education:
In order to reduce the prevalence of viral hepatitis in hemodialysis centers, more adherence to protective measures are highly recommended.
Please cite this paper as:
Zahedi MJ, Darvish Moghadam S, Alavian SM, Dalili M. Seroprevalence of Hepatitis B, C, D and HIV Infection Among Hemodialysis Patients in Kerman Province, South-East Iran. Hepat Mon. 2012;12(5):339-42. DOI: 10.5812/hepatmon.5969
Copyright © 2012 Kowsar Corp. All rights reserved.
Copyright
© 2012, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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