International Journal of Cancer Management

The Official Journal of Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences

e-ISSN 2538-497X

p-ISSN 2538-4422

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Chrysin-loaded folate conjugated PF127-F68 mixed micelles with enhanced oral bioavailability and anticancer activity against human breast cancer cells

Drug Development and Industrial Pharmacy 45(5) (2019)

Debjani Baidya; Jeetendra Kushwaha; Kakasaheb Mahadik; Sharvil Patil

Flavonoids and miRNA Modulation: A Novel Approach to Managing Cancer, Diabetes, Depression, and Neurological Disorders

BioMed Research International 2026(1) (2026)

Mohadese Mahdie; Sedigheh Momenzadeh; Somayeh Reiisi; Razieh Heidari; Poorani Gurumallesh Prabu

Chrysin nanocapsules with dual anti-glycemic and anti-hyperlipidemic effects: Chemometric optimization, physicochemical characterization and pharmacodynamic assessment

International Journal of Pharmaceutics 592 (2021)

Diana El-Hussien; Ghada M. El-Zaafarany; Maha Nasr; Omaima Sammour

The potential use of microRNAs as a therapeutic strategy for SARS-CoV-2 infection

Archives of Virology 166(10) (2021)

Jiulue Hu; Jelena Stojanović; Saman Yasamineh; Pooneh Yasamineh; Sathish Kumar Karuppannan; Mohammed Junaid Hussain Dowlath; Hamed Serati-Nouri

Designing of fucosylated dendrimers as a biocompatible carrier for the targeted delivery of chrysin to human lung cancer cells

Next Materials 5 (2024)

Divya Bharti Rai; Raghu Solanki; Sunita Patel; Deep Pooja; Hitesh Kulhari

An update on nanoparticle-based contrast agents in medical imaging

Artificial Cells, Nanomedicine, and Biotechnology 46(6) (2018)

Neda Naseri; Elham Ajorlou; Fatemeh Asghari; Younes Pilehvar-Soltanahmadi

Nanoscale modification of chrysin for improved of therapeutic efficiency and cytotoxicity

Artificial Cells, Nanomedicine, and Biotechnology 46(sup1) (2018)

Ghassan M. Sulaiman; Majid S. Jabir; Anaheed H. Hameed

Effects of nano-encapsulated curcumin-chrysin on telomerase, MMPs and TIMPs gene expression in mouse B16F10 melanoma tumour model

Artificial Cells, Nanomedicine, and Biotechnology 46(sup2) (2018)

Fatemeh Tavakoli; Rana Jahanban-Esfahlan; Khaled Seidi; Masoumeh Jabbari; Ramezan Behzadi; Younes Pilehvar-Soltanahmadi; Nosratollah Zarghami

Herbal nanomedicines: Recent advancements, challenges, opportunities and regulatory overview

Phytomedicine 96 (2022)

Parusu Kavya Teja; Jinal Mithiya; Abhijeet S. Kate; Khemraj Bairwa; Siddheshwar K Chauthe

Potentiation of Folate-Functionalized PLGA-PEG nanoparticles loaded with metformin for the treatment of breast Cancer: possible clinical application

Molecular Biology Reports 50(4) (2023)

Davoud Jafari-Gharabaghlou; Mehdi Dadashpour; Omid Joodi khanghah; Elnaz Salmani-Javan; Nosratollah Zarghami

In vitro anticancer efficacy of Metformin-loaded PLGA nanofibers towards the post-surgical therapy of lung cancer

Journal of Drug Delivery Science and Technology 61 (2021)

Shadi Samadzadeh; Hanieh Mousazadeh; Somayyeh Ghareghomi; Mehdi Dadashpour; Mirzaagha Babazadeh; Nosratollah Zarghami

A Mechanistic Insight on Phytoconstituents Delivering Hypoglycemic Activity: A Comprehensive Overview

Future Pharmacology 2(4) (2022)

Shraddha Singh Raghav; Bhavna Kumar; Neeraj Kumar Sethiya; Ankur Kaul

Silibinin-loaded magnetic nanoparticles inhibit hTERT gene expression and proliferation of lung cancer cells

Artificial Cells, Nanomedicine, and Biotechnology 45(8) (2017)

Soumaye Amirsaadat; Younes Pilehvar-Soltanahmadi; Faraz Zarghami; Shahriar Alipour; Zohreh Ebrahimnezhad; Nosratollah Zarghami

Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin

Cancer Cell International 21(1) (2021)

Marjan Talebi; Mohsen Talebi; Tahereh Farkhondeh; Jesus Simal-Gandara; Dalia M. Kopustinskiene; Jurga Bernatoniene; Saeed Samarghandian

Chrysin Effect in Prevention of Acetaminophen-Induced Hepatotoxicity in Rat

Chemical Research in Toxicology 32(11) (2019)

Arezoo Mohammadi; Sohrab Kazemi; Mohammad Hosseini; Hoseyn Najafzadeh Varzi; Farideh Feyzi; Payam Morakabati; Ali Akbar Moghadamnia

The role of flavonoids in the regulation of epithelial‐mesenchymal transition in cancer: A review on targeting signaling pathways and metastasis

Medicinal Research Reviews 43(6) (2023)

Carina Proença; Marisa Freitas; Daniela Ribeiro; Ana T. Rufino; Eduarda Fernandes; José Miguel P. Ferreira de Oliveira

Development and physicochemical, toxicity and immunogenicity assessments of recombinant hepatitis B surface antigen (rHBsAg) entrapped in chitosan and mannosylated chitosan nanoparticles: as a novel vaccine delivery system and adjuvant

Artificial Cells, Nanomedicine, and Biotechnology 46(sup1) (2018)

Mohsen Mehrabi; Naser Mohammadpour Dounighi; Seyed Mahdi Rezayat Sorkhabadi; Delaram Doroud; Amir Amani; Mehdi Khoobi; Soheila Ajdary; Younes Pilehvar-Soltanahmadi

SP94-Targeted Triblock Copolymer Nanoparticle Delivers Thymidine Kinase–p53–Nitroreductase Triple Therapeutic Gene and Restores Anticancer Function against Hepatocellular Carcinoma in Vivo

ACS Applied Materials & Interfaces 12(10) (2020)

Uday K. Sukumar; Jagadesh Chandra Bose Rajendran; Sanjiv S. Gambhir; Tarik F. Massoud; Ramasamy Paulmurugan

A comprehensive review of molecular targets, pharmacodynamics, and clinical translation of Chrysin: Unlocking the therapeutic potential

Pharmacological Research - Natural Products 11 (2026)

Ghanshyam Mapare; Sateesh Belemkar

Supercritical antisolvent process-assisted fabrication of chrysin-polyvinylpyrrolidone sub-microparticles for improved anticancer efficiency

The Journal of Supercritical Fluids 162 (2020)

Yu-Jing Pan; Pei-Yao Xu; Biao-Qi Chen; Chao-Ping Fu; Ranjith Kumar Kankala; Ai-Zheng Chen; Shi-Bin Wang

Methods of miRNA delivery and possibilities of their application in neuro-oncology

Non-coding RNA Research 8(4) (2023)

Ilgiz Gareev; Ozal Beylerli; Rasim Tamrazov; Tatiana Ilyasova; Alina Shumadalova; Weijie Du; Baofeng Yang

EphA2-specific microvesicles derived from tumor cells facilitate the targeted delivery of chemotherapeutic drugs for osteosarcoma therapy

Journal of Nanobiotechnology 22(1) (2024)

Zhenggang Wang; Zhiyi He; Junlai Wan; Anmin Chen; Peng Cheng; Wentao Zhu

Improving Anticancer Activity of Chrysin using Tumor Microenvironment pH-Responsive and Self-Assembled Nanoparticles

ACS Omega 7(18) (2022)

Ashok Kumar Jangid; Raghu Solanki; Sunita Patel; Kanakaraju Medicherla; Deep Pooja; Hitesh Kulhari

Osteoprotective effects of flavonoids: Evidence from in vivo and in vitro studies (Review)

Molecular Medicine Reports 25(6) (2022)

Lili Cao; Jiawei Wang; Yujuan Zhang; Feng Tian; Chunfang Wang

Doxorubicin and chrysin combination chemotherapy with novel pH-responsive poly [(lactide-co-glycolic acid)-block-methacrylic acid] nanoparticle

Journal of Drug Delivery Science and Technology 46 (2018)

Sepideh Jabbari; Aliyeh Ghamkhari; Yousef Javadzadeh; Roya Salehi; Soodabeh Davaran

The Antimicrobial, Antioxidative, and Anti-Inflammatory Effects of Polycaprolactone/Gelatin Scaffolds Containing Chrysin for Regenerative Endodontic Purposes

Stem Cells International 2021 (2021)

Mahdieh Alipour; Bahareh Pouya; Zahra Aghazadeh; Hossein SamadiKafil; Marjan Ghorbani; Sara Alizadeh; Marziyeh Aghazadeh; Elaheh Dalir Abdolahinia; Andrea Ballini

Synthesis and structural characterization of Zn(II)–chrysin-phen complexes with tunable coordination architectures and notable antitumor activity

Inorganic Chemistry Communications 188 (2026)

Ariana C.F. Santos; Ricardo F. Mendes; Diana Salvador; Filipe A. Almeida Paz; Dmitry Chernyshov; Adriana C.C. Gomes; Paul J. Gates; João Rocha; Helena Oliveira; Fátima Martel; Carmen S.R. Freire; Bárbara J.M.Leite Ferreira

Tissue Engineering Scaffolds Loaded With a Variety of Plant Extracts: Novel Model in Breast Cancer Therapy

Breast Cancer: Basic and Clinical Research 18 (2024)

Reyhaneh Azhari Rad; Yasaman Naghdi; Mobina Majidi Jamalabadi; Sima Masoumi; Leila Rezakhani; Morteza Alizadeh

Macrophage repolarization using CD44-targeting hyaluronic acid–polylactide nanoparticles containing curcumin

Artificial Cells, Nanomedicine, and Biotechnology (2017)

Raana Farajzadeh; Nosratollah Zarghami; Hamed Serati-Nouri; Zahra Momeni-Javid; Taher Farajzadeh; Sepideh Jalilzadeh-Tabrizi; Shima Sadeghi-Soureh; Neda Naseri; Younes Pilehvar-Soltanahmadi

Chrysin targets aberrant molecular signatures and pathways in carcinogenesis (Review)

World Academy of Sciences Journal 6(5) (2024)

Ritu Raina; Ravinder Bhatt; Arif Hussain

Synergistic Antiproliferative Effects of Co-nanoencapsulated Curcumin and Chrysin on MDA-MB-231 Breast Cancer Cells Through Upregulating miR-132 and miR-502c

Nutrition and Cancer 71(7) (2019)

Naser Javan; Mohammad Hassan Khadem Ansari; Mehdi Dadashpour; Mehran Khojastehfard; Milad Bastami; Mohammad Rahmati-Yamchi; Nosratollah Zarghami

Metformin and Silibinin co-loaded PLGA-PEG nanoparticles for effective combination therapy against human breast cancer cells

Journal of Drug Delivery Science and Technology 61 (2021)

Soumaye Amirsaadat; Davoud Jafari-Gharabaghlou; Sepideh Alijani; Hanieh Mousazadeh; Mehdi Dadashpour; Nosratollah Zarghami

Pioneering Cu(II)-flavonoid coordination polymers with anticancer activity

Inorganic Chemistry Communications 182 (2025)

Ariana C.F. Santos; Francisca Carmo; Ricardo F. Mendes; Dmitry Chernyshov; Filipe A.A. Paz; João Rocha; Fátima Martel; Carmen S.R. Freire; B.J.M. Leite Ferreira

Design and optimization various formulations of PEGylated niosomal nanoparticles loaded with phytochemical agents: potential anti-cancer effects against human lung cancer cells

Pharmacological Reports 75(2) (2023)

Rasoul Shahbazi; Davoud Jafari-Gharabaghlou; Zohreh Mirjafary; Hamid Saeidian; Nosratollah Zarghami

Recent advances on nanomaterials-based fluorimetric approaches for microRNAs detection

Materials Science and Engineering: C 104 (2019)

Mahdi Norouzi; Saman Yasamineh; Maryam Montazeri; Mehdi Dadashpour; Roghayeh Sheervalilou; Mozhgan Abasi; Younes Pilehvar-Soltanahmadi

Co-Delivery of Curcumin and Chrysin by Polymeric Nanoparticles Inhibit Synergistically Growth and hTERT Gene Expression in Human Colorectal Cancer Cells

Nutrition and Cancer 69(8) (2017)

Javid Lotfi-Attari; Younes Pilehvar-Soltanahmadi; Mehdi Dadashpour; Shahriar Alipour; Raana Farajzadeh; Shahrzad Javidfar; Nosratollah Zarghami

Chrysin a promising anticancer agent: recent perspectives

International Journal of Food Properties 26(1) (2023)

Muhammad Shahbaz; Hammad Naeem; Muhammad Imran; Hammad Ul Hassan; Suliman A. Alsagaby; Waleed Al Abdulmonem; Ahmed Bilal Waqar; Ahmed H. Ghorab; Mohamed A. Abdelgawad; Mohammed M. Ghoneim; Muzzamal Hussain; Entessar Al Jbawi; Amna Ihsan

Synthesis and characterization of novel P(HEMA-LA-MADQUAT) micelles for co-delivery of methotrexate and Chrysin in combination cancer chemotherapy

Journal of Biomaterials Science, Polymer Edition 29(11) (2018)

Soodabeh Davaran; Hamed Fazeli; Aliyeh Ghamkhari; Fariborz Rahimi; Ommoleila Molavi; Maryam Anzabi; Roya Salehi

The relationship between microRNAs and Rab family GTPases in human cancers

Journal of Cellular Physiology 234(8) (2019)

Arman Shahabi; Behrooz Naghili; Khalil Ansarin; Nosratollah Zarghami

PEGylation of Chrysin Improves Its Water Solubility while Preserving the In Vitro Biological Activity

Journal of Agricultural and Food Chemistry 71(49) (2023)

Julia Oggero; Fátima B. Gasser; Silvia M. Zacarías; Patricia Burns; María E. Baravalle; Maria Sol Renna; Hugo H. Ortega; Santiago E. Vaillard; Victoria A. Vaillard

Chrysin-loaded PLGA nanoparticles alleviate the implantation of endometriotic lesions via attenuation of peritoneal inflammation and downregulating NF-κB activation-driven expression of angiogenic factors

Journal of Drug Delivery Science and Technology 109 (2025)

Mohamed A. Kotb; Islam Ahmed Abdelmawgood; Amr Ahmed WalyEldeen; Mennatallah H. Abdelaziz; Marina Lotfy Khalaf; Ayman Saber Mohamed; Ahmed Emam Dakrory; Sherif Abdelaziz Ibrahim

Long-term proliferation and delayed senescence of bone marrow-derived human mesenchymal stem cells on metformin co-embedded HA/Gel electrospun composite nanofibers

Journal of Drug Delivery Science and Technology 80 (2023)

Somayeh Ahmadi; Mehdi Dadashpour; Abdolreza Abri; Nosratollah Zarghami

Chrysin loaded novasomes for enhanced wound healing management: In-vitro/ in-vivo evaluation

Journal of Drug Delivery Science and Technology 108 (2025)

Abeer Salama; Asmaa Badawy Darwish; Rania Elgohary; Marwa Anwar Wagdi

Flavonoids and Gastric Cancer Therapy: From Signaling Pathway to Therapeutic Significance

Drug Design, Development and Therapy Volume 18 (2024)

Jiaying Cai; Xiyue Tan; Qichao Hu; Huafeng Pan; Maoyuan Zhao; Cui Guo; Jinhao Zeng; Xiao Ma; Yanling Zhao

Targeted delivery of silibinin via magnetic niosomal nanoparticles: potential application in treatment of colon cancer cells

Frontiers in Pharmacology 14 (2023)

Golchin Shafiei; Davoud Jafari-Gharabaghlou; Mahdi Farhoudi-Sefidan-Jadid; Effat Alizadeh; Marziyeh Fathi; Nosratollah Zarghami

Antioxidant effects of chrysin-loaded electrospun nanofibrous mats on proliferation and stemness preservation of human adipose-derived stem cells

Cell and Tissue Banking 18(4) (2017)

Yaghoub Deldar; Faraz Zarghami; Younes Pilehvar-Soltanahmadi; Mehdi Dadashpour; Nosratollah Zarghami

Enhanced anti-cancer effect of curcumin loaded-niosomal nanoparticles in combination with heat-killed Saccharomyces cerevisiae against human colon cancer cells

Journal of Drug Delivery Science and Technology 80 (2023)

Mahdi Farhoudi Sefidan Jadid; Davoud Jafari-Gharabaghlou; Mohammad Kazem Bahrami; Esat Bonabi; Nosratollah Zarghami

The Expression and Clinicopathologic Significance of Mir-22 in Gastric Cancer

World Journal of Cancer Research 09(02) (2019)

仪唐

Enhanced anti-proliferative and pro-apoptotic effects of metformin encapsulated PLGA-PEG nanoparticles on SKOV3 human ovarian carcinoma cells

Artificial Cells, Nanomedicine, and Biotechnology 47(1) (2019)

Leila Faramarzi; Mehdi Dadashpour; Hadi Sadeghzadeh; Majid Mahdavi; Nosratollah Zarghami

Synergistic anticancer effects of electrospun nanofiber-mediated codelivery of Curcumin and Chrysin: Possible application in prevention of breast cancer local recurrence

Journal of Drug Delivery Science and Technology 55 (2020)

Sara Rasouli; Maryam Montazeri; Samira Mashayekhi; Shima Sadeghi-Soureh; Mehdi Dadashpour; Hanieh Mousazadeh; Abbas Nobakht; Nosratollah Zarghami; Younes Pilehvar-Soltanahmadi

An in vitro examination of the antioxidant, cytoprotective and anti-inflammatory properties of chrysin-loaded nanofibrous mats for potential wound healing applications

Artificial Cells, Nanomedicine, and Biotechnology 46(4) (2018)

Yaghoub Deldar; Younes Pilehvar-Soltanahmadi; Mehdi Dadashpour; Soheila Montazer Saheb; Mohammad Rahmati-Yamchi; Nosratollah Zarghami

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Potential application of inorganic nano-materials in modulation of macrophage function: Possible application in bone tissue engineering

Heliyon 9(6) (2023)

Mohsen Mofarrah; Davoud Jafari-Gharabaghlou; Mahdi Farhoudi-Sefidan-Jadid; Nosratollah Zarghami

Soft nanoparticles for chrysin delivery: an evidence mapping of nanocarrier strategies and biological applications

Drug Delivery and Translational Research 16(10) (2026)

Milena Luiza da Silva; Giovanna Araujo de Morais Trindade; Wellington Martins de Carvalho Ragassi; Marcel Henrique Marcondes Sari; Jéssica Brandão Reolon; Roberto Pontarolo; Luana Mota Ferreira

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Research Progress of Scutellaria baicalensis in the Treatment of Gastrointestinal Cancer

Integrative Cancer Therapies 23 (2024)

Lankang Wang; Baoyi Ni; Jia Wang; Jilai Zhou; Junyi Wang; Jiakang Jiang; Yutong Sui; Yaoyao Tian; Feng Gao; Yufeng Lyu

Chrysin Effect Against Gastric Cancer: Focus on its Molecular Mechanisms

Current Molecular Pharmacology 16(7) (2023)

Seyyed Mohammad Matin Alavi Dana; Tahereh Farkhondeh; Michael Aschner; Majid Darroudi; Helia Samini; Saeed Samarghandian

Using miR-10b, miR-1 and miR-30a expression profiles of bronchoalveolar lavage and sputum for early detection of non-small cell lung cancer

Biomedicine & Pharmacotherapy 88 (2017)

Roghayeh Sheervalilou; Amir Mahdi Khamaneh; Akbar Sharifi; Masoud Nazemiyeh; Ali Taghizadieh; Khalil Ansarin; Nosratollah Zarghami