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International Journal of Endocrinology and Metabolism
Research Institute for Endocrine Sciences
e-ISSN 1726-9148
p-ISSN 1726-913X
The Association of Carotid Intima-Media Thickness and Postprandial Dyslipidemia in Patients with Type 2 Diabetes
Authors
1Medical Education & Development Centre, Iran University of Medical Sciences, I.R.Iran
2Medical Education & Development Centre, Iran University of Medical Sciences, Tehran, I.R.Iran
3Medical Education & Development Centre, Iran University of Medical Sciences, baradaran@iums.ac.ir, I.R.Iran
*Corresponding Author: Medical Education & Development Centre, Iran University of Medical Sciences, baradaran@iums.ac.ir, I.R.Iran. Email: baradaran@iums.ac.ir
Published online:Jan 31, 2007
Article type:Research Article
Received:Sep 06, 2006
Accepted:Dec 06, 2006
How to Cite:Khamseh M, Soltani K, Rafiee J, Mokhber A, Baradaran H. The Association of Carotid Intima-Media Thickness and Postprandial Dyslipidemia in Patients with Type 2 Diabetes. Int J Endocrinol Metab. 2007;5(1):. doi:
Abstract
This research aimed at investigating the correla-tion between postprandial dyslipidemia and ca-rotid intimae-media thickness in people with dia-betes. Materials and Methods: In 28 diabetic patients and 22 age and sex- matched healthy adults, the carotid intimae-media thickness was measured using Doppler ultrasound. Blood glucose, total cholesterol, triglycerides, LDL and HLD choles-terol level were measured after overnight fasting and again 4 hours after a standard high-fat meal. Results: The carotid intimae-media thickness of diabetic patients was greater than normal sub-jects (0.96±0.29 mm vs. 0.75±0.17 mm, respec-tively p=0.008). Diabetic patients showed post-prandial hypertriglyceridemia (P=0.03). In pa-tients with fasting hyperglycemia and postpran-dial hypertriglyceridemia, carotid intimae-media thickness was greater than in patients with nor-mal levels (p=0.04 and p=0.03 respectively). Conclusion: Postprandial hypertriglyceridemia and fasting hyperglycemia may be an independ-ent risk factor for early atherosclerosis and macrovascular disease in individuals with type 2 diabetes.
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Copyright
© 2007, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.
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