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104 resultsUpdated October 25, 2026
1

Pharmaceutical Applications of Hot-Melt Extrusion: Part I

Drug Development and Industrial Pharmacy 33(9) (2007)

Michael M. Crowley; Feng Zhang; Michael A. Repka; Sridhar Thumma; Sampada B. Upadhye; Sunil Kumar Battu; James W. McGinity; Charles Martin

2

Current trends and future perspectives of solid dispersions containing poorly water-soluble drugs

European Journal of Pharmaceutics and Biopharmaceutics 85(3) (2013)

Chau Le-Ngoc Vo; Chulhun Park; Beom‐Jin Lee

3

Oral lipid-based formulations

Advanced Drug Delivery Reviews 59(7) (2007)

David J. Hauss

4

Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation

AAPS PharmSciTech 17(1) (2015)

Hemlata Patil; Roshan V. Tiwari; Michael A. Repka

5

Thin films as an emerging platform for drug delivery

Asian Journal of Pharmaceutical Sciences 11(5) (2016)

Sandeep Karki; Hyeongmin Kim; Seon-Jeong Na; Dohyun Shin; Kanghee Jo; Jaehwi Lee

6

Advanced dielectric polymers for energy storage

Energy storage materials 44 (2021)

Xudong Wu; Xin Chen; Qi Zhang; Daniel Qi Tan

8

Hot melt extrusion (HME) for amorphous solid dispersions: Predictive tools for processing and impact of drug–polymer interactions on supersaturation

European Journal of Pharmaceutical Sciences 48(3) (2012)

Ashish L. Sarode; Harpreet K. Sandhu; Navnit H. Shah; Waseem A. Malick; Hossein Zia

9

3D food printing of as the new way of preparing food: A review

International Journal of Gastronomy and Food Science 22 (2020)

Sylvester Mantihal; Kobun Rovina; Boon‐Beng Lee

10

Applications of hot-melt extrusion for drug delivery

Expert Opinion on Drug Delivery 5(12) (2008)

Michael A. Repka; Soumyajit Majumdar; Sunil Kumar Battu; Ramesh Srirangam; Sampada B. Upadhye

11

Preparation of carbamazepine–Soluplus® solid dispersions by hot-melt extrusion, and prediction of drug–polymer miscibility by thermodynamic model fitting

European Journal of Pharmaceutics and Biopharmaceutics 84(1) (2013)

Jelena Djuriš; Ioannis Nikolakakis; Svetlana R. Ibric; Zorica Djurić; Kyriakos Kachrimanis

12

A review of pharmaceutical extrusion: Critical process parameters and scaling-up

International Journal of Pharmaceutics 479(1) (2014)

Justine Thiry; Fabrice Krier; Brigitte Évrard

13

Raman spectroscopy for the in-line polymer–drug quantification and solid state characterization during a pharmaceutical hot-melt extrusion process

European Journal of Pharmaceutics and Biopharmaceutics 77(1) (2010)

Lien Saerens; Lien Dierickx; Bruno Lenain; Chris Vervaet; Jean Paul Remon; Thomas De Beer

14

Roadmap to 3D-Printed Oral Pharmaceutical Dosage Forms: Feedstock Filament Properties and Characterization for Fused Deposition Modeling

Journal of Pharmaceutical Sciences 108(1) (2018)

Johanna Aho; Johan Peter Boetker; Natalja Genina; Magnus Edinger; Lærke Arnfast; Jukka Rantanen

15

Recent development, challenges, and prospects of extrusion technology

Future Foods 3 (2021)

Krishna Prabha; Payel Ghosh; S. Abdullah; Rosmin M Joseph; Reshma Krishnan; Sandeep Rana; Rama Chandra Pradhan

16

Controlled Release Systems Containing Solid Dispersions: Strategies and Mechanisms

Pharmaceutical Research 28(10) (2011)

Phuong H.L. Tran; Thao T.D. Tran; Jun-Bom Park; Beom‐Jin Lee

17

How water acting as both blowing agent and plasticizer affect on starch-based foam

Industrial Crops and Products 134 (2019)

Linghan Meng; Hongsheng Liu; Long Fei Yu; Qingfei Duan; Ling Chen; Fengsong Liu; Z Z Shao; Kelei Shi; X Y Lin

18

Novel evaluation technology for the demand characteristics of 3D food printing materials: a review

Critical Reviews in Food Science and Nutrition 62(17) (2021)

Qiyong Jiang; Min Zhang; ARUN SADASHIV MUJUMDAR

19

Improved dissolution behavior of lipophilic drugs by solid dispersions: the production process as starting point for formulation considerations

Expert Opinion on Drug Delivery 8(9) (2011)

Parinda Srinarong; Hans de Waard; Henderik Willem Frijlink; Wouter L.J. Hinrichs

20

In-line NIR spectroscopy for the understanding of polymer–drug interaction during pharmaceutical hot-melt extrusion

European Journal of Pharmaceutics and Biopharmaceutics 81(1) (2012)

Lien Saerens; Lien Dierickx; Thomas Quinten; Peter Adriaensens; Robert Carleer; Chris Vervaet; Jean Paul Remon; Thomas De Beer

21

Hierarchical fibrous structures for muscle‐inspired soft‐actuators: A review

Applied Materials Today 20 (2020)

Carlo Gotti; Alberto Sensini; Andrea Zucchelli; Raffaella Carloni; Maria Letizia Focarete

22

Fused Deposition Modelling of Polymer Composite: A Progress

Polymers 15(1) (2022)

J Mogan; Wan Sharuzi Wan Harun; K. Kadirgama; Devarajan Ramasamy; Farhana Mohd Foudzi; Abu Bakar Sulong; Faris Tarlochan; Faiz Ahmad

23

Machine Learning for Process Monitoring and Control of Hot-Melt Extrusion: Current State of the Art and Future Directions

Pharmaceutics 13(9) (2021)

Nimra Munir; Michael Nugent; Darren A. Whitaker; Marion McAfee

24

Insights into powder coating excellence: Unveiling the effects of particle-size distribution

Progress in Organic Coatings 197 (2024)

Xinping Zhu; Junqing Xie; Haiping Zhang; Haiping Zhang; Wei Liu; Hui Zhang; Hui Zhang; Jesse Zhu

25

Influence of formulation and process parameters on the release characteristics of ethylcellulose sustained-release mini-matrices produced by hot-melt extrusion

European Journal of Pharmaceutics and Biopharmaceutics 69(1) (2007)

Ellen Verhoeven; Thomas R. M. De Beer; Guy Van den Mooter; Jean Paul Remon; Chris Vervaet

26

Solvent-Free Melting Techniques for the Preparation of Lipid-Based Solid Oral Formulations

Pharmaceutical Research 32(5) (2015)

Karin Becker; Sharareh Salar-Behzadi; Andreas Zimmer

27

Hot melt extrusion: An industrially feasible approach for casting orodispersible film

Asian Journal of Pharmaceutical Sciences 10(4) (2015)

Rushiraj Jani; Dasharath M. Patel

28

Industrially feasible alternative approaches in the manufacture of solid dispersions: A technical report

AAPS PharmSciTech 7(4) (2006)

Hamsaraj Karanth; Vikram Subraya Shenoy; Rayasa Ramachandra Murthy

29

Process monitoring and visualization solutions for hot-melt extrusion: a review

Journal of Pharmacy and Pharmacology 66(2) (2013)

Lien Saerens; Chris Vervaet; Jean Paul Remon; Thomas De Beer

30

3D printing technologies and composite materials for structural applications

Elsevier eBooks (2018)

Rajkumar Velu; Félix Raspall; Sarat Singamneni

33

Additive Manufacturing of Oral Tablets: Technologies, Materials and Printed Tablets

Pharmaceutics 13(2) (2021)

Alperen Abaci; Christina Gedeon; Anna Kuna; Murat Güvendiren

35

New investigation of distribution imaging and content uniformity of very low dose drugs using hot-melt extrusion method

International Journal of Pharmaceutics 458(2) (2013)

Jun-Bom Park; Chin-Yang Kang; Wie‐Soo Kang; Han‐Gon Choi; Hyo‐Kyung Han; Beom‐Jin Lee

36

Specific mechanical energy – An essential parameter in the processing of amorphous solid dispersions

Advanced Drug Delivery Reviews 173 (2021)

Stephen A. Thompson; Robert O. Williams

37

Formulation and evaluation of cold-extruded chocolate ganache for three-dimensional food printing

Journal of Food Engineering 314 (2021)

Sun Min Kim; Jung Hee Woo; Hyun Woo Kim; Hyun Jin Park

38

Application of Hot Melt Extrusion for Poorly Water-Soluble Drugs: Limitations, Advances and Future Prospects

Current Pharmaceutical Design 20(3) (2014)

Ming Lü; Zhefei Guo; Yongcheng Li; Huishi Pang; Ling Lin; Xu Liu; Xin Pan; Chuanbin Wu

39

PAT tools for the control of co-extrusion implants manufacturing process

International Journal of Pharmaceutics 458(1) (2013)

Fabrice Krier; Jérôme Mantanus; Pierre‐Yves Sacré; Pierre-François Chavez; Justine Thiry; Aude Pestieau; Eric Rozet; Eric Ziémons; Philippe Hubert; Brigitte Évrard

40

The development of an inline Raman spectroscopic analysis method as a quality control tool for hot melt extruded ramipril fixed-dose combination products

International Journal of Pharmaceutics 566 (2019)

Gavin P. Andrews; David S. Jones; Zoé Senta-Loys; Ammar Almajaan; S. Li; Olivier P. Chevallier; Christopher Elliot; Anne Marie Healy; Jeremiah Kelleher; Atif M. Madi; Gareth C. Gilvary; Yiwei Tian

41

Twin screw granulation: Understanding the mechanism of granule formation along the barrel length

Process Safety and Environmental Protection 110 (2016)

Sushma Lute; Ranjit M. Dhenge; Michael J. Hounslow; Agba D. Salman

42

Hot melt extrusion: An emerging manufacturing method for slow and sustained protein delivery

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology 13(5) (2021)

Yi Zheng; Jonathan K. Pokorski

43

Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair

Pharmaceutics 13(8) (2021)

Eliana B. Souto; Cristiana Maria Pedroso Yoshida; Gislaine Ricci Leonardi; Amanda C. Cano; Elena Sánchez‐López; Aleksandra Zielińska; César Viseras; Patrícia B. Severino; Classius Ferreira da Silva; Raquel de Melo Barbosa

44

Physical Properties of Shellac Material Used for Hot Melt Extrusion with Potential Application in the Pharmaceutical Industry

Polymers 13(21) (2021)

Guangming Yan; Zhi Qiang Cao; Declan M. Devine; Manfred Penning; Noel Gately

45

Solid Dispersion as a Technical Solution to Boost the Dissolution Rate and Bioavailability of Poorly Water-Soluble Drugs

Indian Journal of Pharmaceutical Education and Research 55(2s) (2021)

Mohamed Salah Attia; Azza Ali Hasan; Fakhr-eldin S. Ghazy; Eman Gomaa

46

An Enhanced Water Solubility and Stability of Anthocyanins in Mulberry Processed with Hot Melt Extrusion

International Journal of Molecular Sciences 22(22) (2021)

Eun-Ji Go; Byeong Ryeol Ryu; Su-Ji Ryu; Hyun‐Bok Kim; Hyun–Tai Lee; Jin Woo Kwon; Jong-Suep Baek; Jung Dae Lim

47

Roadmap of Effects of Biowaste-Synthesized Carbon Nanomaterials on Carbon Nano-Reinforced Composites

Catalysts 11(12) (2021)

Bhavana H. Thippeswamy; Anantha Sunil Maligi; Gurumurthy Hegde

48

Hot Melt Extrusion and its Application in 3D Printing of Pharmaceuticals

Current Drug Delivery 18(4) (2020)

Sanjeevani Shekhar Deshkar; Mrunali Rathi; Shital Zambad; Krishnakant Gandhi

49

Narrowing particle size distributions to enhance powder coating performance by improved classifying

Powder Technology 435 (2024)

Xinping Zhu; Wei Liu; Haiping Zhang; Hui Zhang; Jesse Zhu

50

Fabrication of Polypill Pharmaceutical Dosage Forms Using Fused Deposition Modeling 3D Printing: A Systematic Review

Pharmaceutics 16(10) (2024)

Haya Khader Ahmad Yasin; Moawia M. Al-Tabakha; Siok Yee Chan

51

Development and in vitro Evaluation of Cannabidiol Mucoadhesive Buccal Film Formulations Using Hot-Melt Extrusion Technology

Medical Cannabis and Cannabinoids 7(1) (2024)

Iman E. Taha; Mahmoud A. ElSohly; Mohamed M. Radwan; Sundus Omari; Michael A. Repka; Eman A. Ashour

52

Exploring the impact of material selection on the efficacy of hot-melt extrusion

International Journal of Pharmaceutics 668 (2024)

Devesh U. Kapoor; Devendra J. Vaishnav; Rahul Garg; Pushpendra Kumar Saini; Bhupendra Gopalbhai Prajapati; Guillermo Raul Castro; Supakij Suttiruengwong; Sontaya Limmatvapirat; Pornsak Sriamornsak

53

A Comparative Life Cycle Assessment of Hemp-based and Polylactide (PLA) Composite 3D Printing Filaments

Procedia CIRP 135 (2025)

Dolor Roy Enarevba; Nebojsa Jaksic; Karl R. Haapala

54

Rheological and solid-state NMR assessments of copovidone/clotrimazole model solid dispersions

International Journal of Pharmaceutics 500(1-2) (2016)

Fengyuan Yang; Yongchao Su; Lei Zhu; Chad D. Brown; Lawrence A. Rosen; Kenneth J. Rosenberg

55

Use of Placket–Burman Statistical Design to Study Effect of Formulation Variables on the Release of Drug from Hot Melt Sustained Release Extrudates

AAPS PharmSciTech 11(2) (2010)

Satishkumar P. Jain; Pirthi Pal Singh; Sharadchandra D. Javeer; Purnima Dhanraj Amin

56

Informatics calibration of a molecular descriptors database to predict solid dispersion potential of small molecule organic solids

International Journal of Pharmaceutics 418(2) (2011)

Michael D. Moore; Peter L. D. Wildfong

57

Effect of composition in the development of carbamazepine hot-melt extruded solid dispersions by application of mixture experimental design

Journal of Pharmacy and Pharmacology 66(2) (2013)

Jelena Djuriš; Ioannis Nikolakakis; Svetlana R. Ibric; Zorica Djurić; Kyriakos Kachrimanis

58

Evaluation of the Influence of Formulation and Process Variables on Mechanical Properties of Oral Mucoadhesive Films Using Multivariate Data Analysis

BioMed Research International 2014 (2014)

Hana Landová; David Vetchý; Jan Gajdziok; Petr Doležel; Jan Muselík; Kateřina Kubová; Vladimír Jekl; Karel Hauptman; Zdeněk Knotek

59

Influence of molecular weight of carriers and processing parameters on the extrudability, drug release, and stability of fenofibrate formulations processed by hot-melt extrusion

Journal of Drug Delivery Science and Technology 29 (2015)

Bader B. Alsulays; Jun-Bom Park; Sultan Alshehri; Joseph T. Morott; Saad M. Alshahrani; Roshan V. Tiwari; Abdullah Alshetaili; Soumyajit Majumdar; Nigel Langley; Karl Kolter; Andreas Gryczke; Michael A. Repka

60

Physical Characterization of Drug:Polymer Dispersion Behavior in Polyethylene Glycol 4000 Solid Dispersions using a Suite of Complementary Analytical Techniques

Journal of Pharmaceutical Sciences 103(9) (2014)

Dipy M. Vasa; Namita Dalal; Jeffrey M. Katz; Rahul Roopwani; Akshata Nevrekar; Harshil M. Patel; Ira S. Buckner; Peter L. D. Wildfong

61

Controlled Porosity Solubility Modulated Osmotic Pump Tablets of Gliclazide

AAPS PharmSciTech 16(3) (2014)

Arti Banerjee; P. R. P. Verma; Subhash P Gore

62

NOVEL TECHNIQUES OF GRANULATION: A REVIEW

International Research Journal of Pharmacy 7(10) (2016)

P Muralidhar; E. Bhargav; C. Sowmya

63

Formulation and Evaluation of Sustained Release Extrudes Prepared via Novel Hot Melt Extrusion Technique

Journal of Pharmaceutical Innovation 9(3) (2014)

Ravindra Kumar Tiwari; Sunil Kumar Agarwal; Rsr Murthy; Shweta Tiwari

64

Hot-melt extrusion of sugar-starch-pellets

International Journal of Pharmaceutics 493(1-2) (2015)

Chi-Wah Yeung; Hubert Rein

65

A Review Paper on Biodegradable Composites Made from Banana Fibers

Asian Journal of Engineering and Applied Technology 7(2) (2018)

Amrinder Singh Pannu; Sehijpal Singh

66

A Review for Gastro - Retentive Drug Delivery System

Asian Journal of Pharmaceutical Research and Development 11(4) (2023)

Rutuja Patole; Bharatee Chaware; Vishal R Mohite; Vivekkumar K. Redasani

67

MELT GRANULATION: AN ALTERNATIVE TO TRADITIONAL GRANULATION TECHNIQUES

INDIAN DRUGS 50(03) (2013)

UJWALA S. DESAI; P. Chaudhari; Dhaval Bhavsar; R.P. Chavan

68

Preparation of Hot-Melt Extruded Dosage Form for Enhancing Drugs Absorption Based on Computational Simulation

Pharmaceutics 12(8) (2020)

Sung-Min Choi; Sung-Hoon Lee; Chin-Yang Kang; Jun-Bom Park

69

Recycled Plastics Utilization in Packaging Converting Processes: A Semi‐Systematic Review

Advances in Polymer Technology 2026(1) (2026)

Fereshte Mohammadi Khoshoue; Timo Kärki; Ville Leminen

70

PELLETIZATION TECHNIQUES FOR ORAL DRUG DELIVERY

International Journal of Pharmaceutical Sciences and Drug Research (2009)

Jagan Mohan Kandukuri; Allenki Venkatesham; Chandra Mohan Eaga; Vasu Keshetty; Kiran Kumar Jannu

71

Hot-Melt Extrusion (HME): From Process to Pharmaceutical Applications

InTech eBooks (2012)

Mohammed Maniruzzaman; Dennis Douroumis; Joshua Siaw Boateng; John Robert Martin

72

Formulation and Evaluation of Controlled-Release Tablet of Zolpidem Tartrate by Melt Granulation Technique

ISRN Pharmaceutics 2011 (2011)

Shailesh T. Prajapati; Amit N. Patel; Chhagan N. Patel

74

Double-Layered Matrix of Shellac Wax-Lutrol in Controlled Dual Drug Release

AAPS PharmSciTech 17(6) (2015)

Thawatchai Phaechamud; Chai-ek Choncheewa

75

Bioadhesive Films as Drug Delivery Systems

Drug Delivery Letters 11(1) (2020)

Inderbir Singh; Debabrata Ghosh Dastidar; Dipanjan Ghosh; Abhijit Sengupta; Tolulope O. Ajala; Oluwatoyin A. Odeku; Bineet Singh; Madhu Sharma

76

Hot melt extrusion for enhanced dissolution and intestinal absorption of hydrochlorothiazide

Journal of Drug Delivery Science and Technology 88 (2023)

Ebtessam Essa; Manna Amin; Amal A. Sultan; Mona F. Arafa; Gamal Mohamed El Maghraby; Christopher McConville

77

Solubility enhancement using poly(meth)acrylate based solid dispersions

Powder Technology 270 (2014)

Bhavesh B. Patel; Jayvadan K. Patel; Subhashis Chakraborty

78

Buccal Drug Delivery

Springer eBooks (2011)

Michael A. Repka; Li-lan Chen; Rick S. Chan

79

Crystal Growth of Pharmaceuticals from Melt

InTech eBooks (2012)

José S. Redinha; A.J. Lopes

80

The use of hot‐melt extruded corn starch matrices as drug carrier systems: A thermophysical characterization

Starch - Stärke 66(9-10) (2014)

Thomas Kipping; Rita Pereira Trindade; Hubert Rein

81

Review on Hot Melt Extrusion Technology and it's Application

International Journal of Scientific Research in Science and Technology (2019)

Aniruddh Mali; Kaustubh V. Gavali; Ritesh Choudhari; V. P. Anekar; Yogeshkumar Nanasaheb Gavhane

82

Oral Controlled Drug Delivery by Hot-Melt Extrusion Technology

Advances in bioinformatics and biomedical engineering book series (2022)

Divya D. Jain; Srushti M. Tambe; Purnima Dhanraj Amin

83

Fiber extrusion melt-spinning

Elsevier eBooks (2021)

Mukesh Kumar Singh; Annika Singh

84

Preparation of Felodipine–PEG Solid Dispersions by Solvent-Free scCO 2 Processing and Their Translation into Orally Disintegrating Tablets

ACS Omega 11(7) (2026)

Siva Satyanarayana Kolipaka; Laura Andrade Junqueira; Elizabeth J. Pathrapankal; Dennis Douroumis; Vivek Trivedi

85

Formulation and Evaluation of Solid Lipid Nanoparticles for controlled delivery of Zidovudine

Research Journal of Pharmacy and Technology (2021)

Sonia Dhiman; Gurjeet Singh Thakur; Shivangi Anand; Priyanka Yadav

86

Hot-melt extrusion: a versatile technology

Elsevier eBooks (2020)

Mohammed Maniruzzaman; Jaywant N. Pawar

87

Amorphous Drug Formulation

Springer eBooks (2018)

Marzena Rams‐Baron; Renata Jachowicz; E.V. Boldyreva; Deliang Zhou; Witold Jamróz; Marian Paluch

88

Formulation and Evaluation of Microspheres of Diltiazem Hydrochloride by Spray Drying Technique

International Journal of Pharmaceutical Sciences Review and Research (2022)

Shubham R. Kamble; Prafful P. Kothari; Archana Dinkarrao Kajale; M. A Channawar; S.R. Gawande

89

Microparticulate hot melt pallets technology: a review

Journal of Drug Delivery and Therapeutics 8(6-s) (2018)

Shekhar Kokate; Punit R. Rachh