Cover image of the article: Effects of Carbon Sources on Growth and Production of Antifungal Agents by Gymnopilus Spectabilis

Image Credit:Iran J Pharm Res

Effects of Carbon Sources on Growth and Production of Antifungal Agents by Gymnopilus Spectabilis

Authors

Hossein Vahidi1,*, Faraz Mojab1, Nasim Taghavi1
1Department of Pharmacognosy, Shaheed Beheshti Medical University, Tehran, Iran
*Corresponding Author: Department of Pharmacognosy, Shaheed Beheshti Medical University, Tehran, Iran. Email:hovahidi@yahoo.com

Iranian Journal of Pharmaceutical Research:Vol. 5, issue 3; 219-222
Published online:Nov 20, 2010
Article type:Research Article
Received:Jan 21, 2006
Accepted:Jun 21, 2006
How to Cite:Vahidi H, Mojab F, Taghavi N. Effects of Carbon Sources on Growth and Production of Antifungal Agents by Gymnopilus Spectabilis. Iran J Pharm Res. 2022;5(3):e128289. doi: https://doi.org/10.22037/ijpr.2010.679

Abstract

Effects of different carbon sources on growth and production of antifungal agent(s) by Gymnopilus spectabilis were investigated. Different carbon sources including; Glucose, fructose, lactose, maltose, manitol and sucrose at the concentration of 10 g/l and slow releasing carbon sources including malt extract and soluble starch at the concentration of 2g/l were used. Inhibition of spore germination of Aspergillus niger was used to test antifungal activity. The results showed that the highest activity (90% inhibition of spore germination) and biomass concentration (2.4 g/l) were obtained when glucose was used as carbon source. Other media with different carbon sources showed antifungal activity ranging from 30% to 70% inhibition of spore germination. Combination of glucose with malt extract as a slow releasing carbon source was also increased activity to 100% inhibition.

 

 

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Copyright

© 2022, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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