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66 resultsUpdated October 25, 2026
1

Isatin and its derivatives: a survey of recent syntheses, reactions, and applications

MedChemComm 10(3) (2019)

Varun Varun; Sonam Nirwan; Rita Kakkar

2

Biochemical and pharmacological characterization of isatin and its derivatives: from structure to activity

Pharmacological Reports 65(2) (2013)

Parvaneh Pakravan; Soheila Kashanian; Mohammad Mehdi Khodaei; Frances J. Harding

3

Imidazoles as Promising Scaffolds for Antibacterial Activity: A Review

Mini-Reviews in Medicinal Chemistry 13(12) (2013)

Nidhi Rani; Ajay Kumar Sharma; Randhir Singh

4

Isatin containing heterocycles for different biological activities: Analysis of structure activity relationship

Journal of Molecular Structure 1222 (2020)

Rajarshi Nath; Shelly Pathania; Gourav Grover; Md Jawaid Akhtar

5

Synthesis, DFT, and eco-friendly insecticidal activity of some N-heterocycles derived from 4-((2-oxo-1,2-dihydroquinolin-3-yl)methylene)-2-phenyloxazol-5(4H)-one

Bioorganic Chemistry 112 (2021)

Eman A. Ghareeb; Naglaa F. H. Mahmoud; Eman A. A. El‐Bordany; Eman A. E. El‐Helw

6

Design, synthesis and antibacterial activity of new Isatin-based Schiff base derivatives: Molecular docking, POM analysis, in silico pharmacokinetics and identification of antitumor pharmacophore sites

Journal of Molecular Structure 1322 (2024)

Pankaj Meshram; Rajendra S. Dongre; Mukhtar Ahmed; Sumeer Ahmed; Ramalingam Gajendhiran; Aziz Kalilur Rahiman; Taïbi Ben Hadda; Khairi Mustafa Fahelelbom; Ajmal Rashid Bhat; Gabriela Tătărîngă

7

SEARCH FOR BIOLOGICAL ACTIVE ISATINS: A SHORT REVIEW

International Journal of Pharmaceutical Sciences and Drug Research (2010)

Bhanupriya Bhrigu; Devender Pathak; Nadeem Siddiqui; M. S. Alam; Waquar Ahsan

8

Synthesis, in vitro evaluation, and molecular docking studies of novel hydrazineylideneindolinone linked to phenoxymethyl-1,2,3-triazole derivatives as potential α-glucosidase inhibitors

Bioorganic Chemistry 111 (2021)

Diba Shareghi-Boroujeni; Aida Iraji; Somayeh Mojtabavi; Mohammad Ali Faramarzi; Tahmineh Akbarzadeh; Mina Saeedi

9

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SCHIFF’S AND N-MANNICH BASES OF ISATIN AND ITS DERIVATIVES WITH 4-AMINO-N-CARBAMIMIDOYL BENZENE SULFONAMIDE

International Journal of Pharmaceutical Sciences and Drug Research (2010)

U. K. Singh; S. N. Pandeya; A. Singh; B. Srivastava; M. Pandey

10

Green synthesis, antibacterial evaluation and QSAR analysis of some isatin Schiff bases

Journal of Molecular Structure 1208 (2020)

Meryem Chemchem; Rafik Menacer; Naïma Merabet; Hamida Bouridane; Samir Yahiaoui; Sadjia Moussaoui; Lotfi Belkhırı

11

2‐(Hetero(aryl)methylene)hydrazine‐1‐carbothioamides as Potent Urease Inhibitors

Chemical Biology & Drug Design 85(2) (2014)

Aamer Saeed; Aqeel Imran; Pervaiz Ali Channar; Mohammad Shahid; Wajahat Mahmood; Jamshed Iqbal

13

Discovery and Anticancer Activity of Novel 1,3,4-Thiadiazole- and Aziridine-Based Indolin-2-ones via In Silico Design Followed by Supramolecular Green Synthesis

ACS Omega 7(20) (2022)

Prashant Jagannath Chaudhari; Sanjay B. Bari; Sanjay Javerilal Surana; Atul A. Shirkhedkar; Chandrakant G. Bonde; Saurabh C. Khadse; Vinod G. Ugale; Akhil A. Nagar; Rameshwar S. Cheke

14

Synthesis, structure elucidation, biological activity, enzyme inhibition and molecular docking studies of new Schiff bases based on 5-nitroisatin-thiocarbohydrazone

Journal of Molecular Structure 1277 (2022)

Hasan Yakan; Hiba Hassan Sulieman Omer; Osman Buruk; Şükriye Çakmak; Sarmad Marah; Aysel Veyisoğlu; Halit Muğlu; Tevfik Özen; Halil Kütük

15

Advances in Synthesis, Derivatization and Bioactivity of Isatin: A Review

Current Organic Synthesis 18(1) (2020)

Garima Chauhan; Dharam Pal Pathak; Faraat Ali; Rubina Bhutani; Garima Talwar Kapoor; Shaik Khasimbi

16

Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors

Antibiotics 11(8) (2022)

Iram Irfan; Asghar Ali; Bharati Reddi; Mohd. Abrar Khan; Phool Hasan; Sarfraz Ahmed; Amad Uddin; Magdalena E. Piatek; Kevin A. Kavanagh; Qazi Mohd Rizwanul Haque; Shailja Singh; A. Addlagatta; Mohammad Abid

17

Microwave Synthesis, Characterization, and Antimicrobial Activity of Some Novel Isatin Derivatives

Journal of Chemistry 2015(1) (2015)

Ayman El‐Faham; Wael Nabil Hozzein; Mohammad Ahmad Wadaan; Sherine N. Khattab; Hazem A. Ghabbour; Hoong‐Kun Fun; Mohammed Rafiq H. Siddiqui

18

Structure-based design, synthesis, and anticonvulsant activity of isatin-1-N-phenylacetamide derivatives

Medicinal Chemistry Research 23(5) (2013)

Chao Xie; Li-Ming Tang; Fu-Nan Li; Liping Guan; Cheng-Yan Pan; Sihong Wang

19

Effect of Structure on Charge Distribution in the Isatin Anions in Aprotic Environment: Spectral Study

Molecules 22(11) (2017)

Pavol Tisovský; Robert Šándrik; Miroslav Horváth; Jana Donovalová; Klaudia Jakusová; Marek Cigáň; Róbert Sokolík; Anton Gáplovský; Martin Gáplovský; Juraj Filo

20

Synthesis, potential anticonvulsant and antidepressant effects of 2-(5-methyl-2,3-dioxoindolin-1-yl)acetamide derivatives

Acta Pharmaceutica Sinica B 5(4) (2015)

Xing‐Hua Zhen; Peng Zhou; Shui-Lian Zhao; Yan Han; Qinghao Jin; Liping Guan

21

Molecular aspects on the interaction of isatin-3-isonicotinylhydrazone to deoxyribonucleic acid: model for intercalative drug-DNA binding

Molecular Biology Reports 39(4) (2011)

Soheila Kashanian; Mohammad Mehdi Khodaei; Parvaneh Pakravan; Hadi Adibi

23

Synthesis, in vitro α-glucosidase activity and in silico molecular docking study of isatin analogues

Chemical Data Collections 43 (2022)

Hayat Ullah; Fazal Rahim; Ezaz Ullah; Shawkat Hayat; Hussan Zada; Fahad Khan; Abdul Wadood; Faisal Nawaz; Zia Ur Rehman; Syed Adnan Alı Shah

24

Isatin Schiff Base -An Overview

Pharmatutor 6(5) (2018)

D. Visagaperumal; Justin Ebuka Ezekwem; H. Munji; Vineeth Chandy

25

A Review an Isatin, Isatin Derivatives and their Pharmacological Activity

Research Journal of Pharmacology and Pharmacodynamics (2021)

S. Janet Beula; T. Rama Mohan Reddy; R. Suthakaran; K. Suneetha

26

Imidazole: An Emerging Scaffold Showing its Therapeutic Voyage to Develop Valuable Molecular Entities

Current Drug Research Reviews 12(2) (2019)

Bhawna Chopra; Ashwani K. Dhingra; Deo Nandan Prasad

27

5-chloro-3-(2-(2,4-dinitrophenyl) hydrazono)indolin-2-one: synthesis, characterization, biochemical and computational screening against SARS-CoV-2

Chemical Papers 78(6) (2024)

Felicite Majoumo‐Mbe; Neba Abongwa Sangbong; Alain Tadjong Tcho; Cyril T. Namba-Nzanguim; Conrad Veranso Simoben; Donatus Bekindaka Eni; Mustafa Alhaji Isa; Adi Narayana Reddy Poli; Joel A. Cassel; Joseph M. Salvino; Luis J. Montaner; Ian Tietjen; Fidele Ntie‐Kang

29

Nanocubic magnesium oxide: Towards hydrazine sensing

Vacuum 155 (2018)

Rizwan Wahab; Naushad Ahmad; Manawwer Alam; Anees A. Ansari

30

Synthesis and Toxicity Evaluation of Some N4-Aryl Substituted 5-Trifluoromethoxyisatin-3-thiosemicarbazones

Molecules 16(8) (2011)

Humayun Pervez; Naveeda Saira; Mohammad Saeed Iqbal; Muhammad Yaqub; Khalid Mohammed Khan

31

Evaluation of Antioxidant, Antimicrobial and Anticancer activity of Thiazole Tagged Isatin Hydrazones

JOURNAL OF PHARMACEUTICAL CHEMISTRY 3(2) (2016)

Venkateshwarlu Eggadi; Umasankar Kulandaivelu; Sharvana bhava B S; Venkateshwar Rao Jupally

32

Synthesis and biological evaluation of some N 4-aryl-substituted 5-fluoroisatin-3-thiosemicarbazones

Medicinal Chemistry Research 22(12) (2013)

Humayun Pervez; Naveeda Saira; Mohammad Saeed Iqbal; Muhammad Yaqub; Khalid Mohammed Khan

33

Synthesis and application of new reactive disperse dyes based on isatin derivatives and their Antibacterial activity

Egyptian Journal of Chemistry 0(0) (2019)

Mervat S. El-Sedik; Saadia A. Abd El-Megied; Tarek S. Aysha; Safia A. Mahmoud

34

SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME SULFONAMIDE SCHIFF’S BASES

International Journal of Pharmaceutical Sciences and Drug Research (2010)

Umesh K. Singh; Surendra N. Pandeya; Sandeep K. Sethia; M. Pandey; A. Singh; Anuj Garg; Pawan Kumar

35

Progressive applications of synthesized isatin-based reactive dye: fabrics dyeing, corrosion inhibition, and antimicrobial activity

Scientific Reports 15(1) (2025)

Mervat S. El-Sedik; Saadia A. Abd El-Megied; Tarek S. Aysha; Amal M. Abdel‐karim; Bassant Gaber; Safia A. Mahmoud

36

N"-[(3Z)-1-Acetyl-5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene]thiocarbonohydrazide

Molbank 2013(2) (2013)

Nataša Ristovska; Frosa Anastasova; Марина Стефова

37

[Retracted] Microwave Mediated Organic Reaction: A Convenient Approach for Rapid and Efficient Synthesis of Biologically Active Substituted 1,3‐Dihydro‐2H‐indol‐2‐one Derivatives

Journal of Nanomaterials 2013(1) (2013)

Jnyanaranjan Panda; Biswa Mohan Sahoo; Nikunja Kishor Mishra; Sai Krushna Padhi; Jitendriya Mishra

38

Antibacterial Potentiality of Isatin-Containing Hybrid Derivatives: A Review

Asian Journal of Chemistry 35(4) (2023)

Suvaiv; Kuldeep Singh; Praveen Kumar; Syed Misbahul Hasan; Shom Prakash Kushwaha; Arun Kumar; Khatib Sayeed Ismail; Samar Mujeeb; Shubham Kumar Maurya; Syed Mehdi Hasan Zaidi

40

Synthesis and anti-inflammatory effects evaluation of 1,3 substituted isatin derivatives

The Thai Journal of Pharmaceutical Sciences 45(4) (2021)

Farshid Hassanzadeh; Elham Jafari; Nahal Khayambashi; Valiollah Hajhashemi

41

Semiexperimental equilibrium structure of 1-methylisatin from gas-phase electron diffraction data and structural changes in isatin due to 1-methyl and 5-fluoro substituents as predicted by coupled cluster computations

Molecular Physics 117(14) (2018)

Alexander V. Belyakov; Kirill O. Nikolaenko; Alexander A. Oskorbin; Natalja Vogt; Anatolii N. Rykov; Igor F. Shishkov

42

Rh(III)‐Catalyzed [4+1] Cyclization of Sulfoxonium Ylides and Anthranils for Accessing N‐Arylisatins

ChemCatChem 12(18) (2020)

Peng Chao Zhou; Wei‐Tao Yang; Guigen Li; Wen‐Juan Hao; Bo Jiang

43

Anticancer activities and cell death mechanisms of 1H-indole-2,3-dione 3-[N-(4 sulfamoylphenyl)thiosemicarbazone] derivatives

Istanbul Journal of Pharmacy 48(3) (2019)

İdi̇l Çeti̇n; Pınar Eraslan‐Elma; Mehmet Topçul; Nilgün Karalı

44

SYNTHESIS, ANTIBACTERIAL EVALUATION AND DOCKING STUDIES OF SOME NOVEL ISATIN DERIVATIVES

INDIAN DRUGS 55(03) (2018)

Narayanan Venkateshan; R Rajapandi; P. Kaniga

45

N-alkylation methods, Characterization and Evaluation of antibacterial activity of some Novel 5-Chloroisatin Derivative

International Journal of Engineering Research and Applications 07(06) (2017)

Zineb Tribak; O. El Amin; Mohamed Khalid Skalli; Omar Senhaji; Y. Kandri Rodi; Mohammed Houssaini Iraqui

46

Antifouling activity of isonitrosoacetanilides against microfouling and macrofouling

Environmental Science and Pollution Research 30(10) (2022)

Vanessa Ochi Agostini; Sabrina Teixeira Martinez; Erik Muxagata; Alexandre José Macêdo; Grasiela Lopes Leães Pinho

47

Synthesis and Characterization of Some New N-Glycosides of Pyridine-2,6-bis-Carboxamides Derivatives

Nucleosides Nucleotides & Nucleic Acids 35(9) (2016)

Mohammad Emad Azab; Nagy M. Khalifa; Ashraf Ahmed Sediek; Nermein M. Sabry; Mohamed M. Al-Omar; Abd El‐Galil E. Amr

49

STUDIES ON ANTIMICROBIAL AND ANTHELMINTIC POTENTIAL OF ALOE

International Journal of Research in Ayurveda and Pharmacy 3(6) (2012)

Pradeep Kumar Dubey; Rajendra Netam; Neetu Bias; Prachi Khare; Arun Kakkar

50

Benzothiazol Clubbed Imidazol-4-ones as Anti-fungal, Anti-tubercular and Anti-HIV-1 Agents: Their Synthesis and Molecular Docking Study

Letters in Drug Design & Discovery 16(4) (2018)

Navin B. Patel; Asif R. Shaikh; Vatsal M. Patel; Edgar Eduardo Lara-Ramirez; Gildardo Rivera

51

SYNTHESIS, CHARACTERISATION, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF ISATIN DERIVATIVES

International Research Journal of Pharmacy 10(9) (2019)

Anjali .; Devender Pathak; Payal Kamboj; Mohd Amir

53

Synthesis, Spectroscopy, Computational and Anticancer Evaluation of Some Novel Isatin Derivatives

Chemical Sciences Journal 09(03) (2018)

Rabab T Shalof; Eman H. Tawfik; Fadda Aa

55

Molecular Structure Vibrational & Electronic Properties of Some Isatin Derivatives

Karbala International Journal of Modern Science 7(1) (2021)

Fatma K fkandermili; Fatma Aldibashi; Hakan Sezgin Sayıner