Cover image of the article: Shelf Life Prediction of Infant Formula by Using Rancidity Test

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Shelf Life Prediction of Infant Formula by Using Rancidity Test

Authors

Behrooz Jannat1, Mohammad Reza Oveisi2, Naficeh Sadeghi2,*, Abdolazim Behfar3, Mannan Hajimahmoodi2, Forouzandeh Jannat4, Sahar Khoshnamfar2
1Food and Drug Laboratory Research Center, Food and Drug Deputy, Ministry of Health and Medical Education, Tehran, Iran
2Drug and Food Control Department, Faculty of Pharmacy, Tehran University of Medical Sciences
3Bromatology Department, Faculty of Pharmacy, Ahvaz University of Medical Sciences
4Arash Hospital, Tehran University of Medical Sciences
*Corresponding Author: Drug and Food Control Department, Faculty of Pharmacy, Tehran University of Medical Sciences. Email:nsadeghi@sina.tums.ac.ir

Iranian Journal of Pharmaceutical Research:Vol. 7, issue 4; 269-273
Published online:Nov 20, 2010
Article type:Research Article
Received:Aug 01, 2007
Accepted:Aug 01, 2008
How to Cite:Jannat B, Oveisi MR, Sadeghi N, Behfar A, Hajimahmoodi M, et al. Shelf Life Prediction of Infant Formula by Using Rancidity Test. Iran J Pharm Res. 2022;7(4):e128601. doi: https://doi.org/10.22037/ijpr.2010.775

Abstract

Infant formula has a fatty acid composition that meets the needs of the neonates for unsaturated fatty acids.These fatty acids are of major importance during this period of life in which the brain and retina are developing, and will therefore have an influence upon visual acuity and learning abilities.

Oxygen reacts readily with unsaturated fatty acids, so that every time these compounds are handled there is a danger of contaminated with oxidative products. Oxidative stability is an important parameter in characterization of fats and oils.

The purpose of this study was to predict the shelf life of an infant formula using accelerated stability test (rancimat), to save time. The Rancimat method is based on conductometric determination of volatile degradation products and features automatic plotting of the conductivity against time. The evaluation was performed graphically after completion of the experiments.

The stability of a commercially available infant formula in Tehran, Iran was measured using rancimat method at temperatures of 60, 80, 90, 100, 110, 120 and 130 °C.

Equations have been derived by which the shelf life can be predicted on the basis of the Rancimat method, thus avoiding the time-consuming long-term studies. The shelf life of the commercial infant formula studied was estimated as 534 days (approximately 18 months).

Highlights

Copyright

© 2022, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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