Cover image of the article: Antimicrobial Activity of Five Endemic Asperula Species from Turkey

Image Credit:Iran J Pharm Res

Antimicrobial Activity of Five Endemic Asperula Species from Turkey

Authors

Fatih Kalyoncu1,*, Ersin Minareci1, Orkide Minareci1
1Celal Bayar University, Faculty of Science and Arts, Department of Biology, Muradiye- Manisa, Turkey
*Corresponding Author: Celal Bayar University, Faculty of Science and Arts, Department of Biology, Muradiye- Manisa, Turkey. Email:fatih.kalyoncu@bayar.edu.tr

Iranian Journal of Pharmaceutical Research:Vol. 8, issue 4; 263-268
Published online:Nov 20, 2010
Article type:Research Article
Received:Mar 01, 2008
Accepted:Sep 01, 2008
How to Cite:Kalyoncu F, Minareci E, Minareci O. Antimicrobial Activity of Five Endemic Asperula Species from Turkey. Iran J Pharm Res. 2022;8(4):e128647. doi: https://doi.org/10.22037/ijpr.2010.820

Abstract

In this study, methanol and ether extracts of five endemic Asperula species (Rubiaceae) from Turkey (A. antalyensis, A. brevifolia, A. pseudochlorantha, A. purpurea subsp. apiculata and A. serotina), used in the traditional system of medicine, were tested for antimicrobial activity by the agar well diffusion method and the broth dilution method. The most active species were Asperula brevifolia and A. serotina which showed broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria and maximum inhibition was shown by methanol extract of A. antalyensis against Candida albicans as 32 mm. Methanol extracts of Asperula species were among the most active with the MIC values ranging from 7.6 to 14.8 mg/mL.

Highlights

Copyright

© 2022, Author(s). This open-access article is available under the Creative Commons Attribution 4.0 (CC BY 4.0) International License (https://creativecommons.org/licenses/by/4.0/), which allows for unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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