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8 resultsUpdated November 15, 2026
1

Genetic drivers of Chinese hamster ovary cell proliferation revealed by functional genomics

iScience 28(11) (2025)

Jannis Marzluf; Merle Rattay; Maximilian Goertz; Christoph Zehe; Ann‐Cathrin Leroux

2

Optimization of extended Kozak elements enhances recombinant proteins expression in CHO cells

Journal of Biotechnology 392 (2024)

Zheng-Mei Li; Yan Lin; Cong-Hui Luo; Qiu-li Sun; Chunliu Mi; Xiaoyin Wang; Tian-Yun Wang

3

Evaluating Apoptotic Gene Efficiency for CHO Culture Performance Using Targeted Integration

ACS Synthetic Biology 14(5) (2025)

David Catalán-Tatjer; Saravana Kumar Ganesan; Iván Martínez‐Monge; Lise Marie Grav; Jesús Lavado‐García; Lars Keld Nielsen

4

Overexpression of Tgm2 in Chinese Hamster Ovary Cells Enhances Recombinant Monoclonal Antibody Expression and Promotes Cell Proliferation through Reduction of Apoptosis

ACS Synthetic Biology 14(5) (2025)

Huijie Zhang; Qi Zhao; Miao Zhang; Lu−Lu Yang; Jumai Abiti; Mingming Han; Yanping Gao; Jiang‐Tao Lu; Jianing Wang; Mengying Ji; Xi Zhang; Wen Wang; Le-Le Qiu; Xiao-Yin Wang; Tian-Yun Wang; Yan‐Long Jia

5

Engineering of the Caspase-3 Gene in Recombinant CHO Cells Caused More Apoptosis Resistance and enhanced Recombinant Protein Production Than the BAX Gene

Iranian Biomedical Journal 29(3) (2025)

A Rahimi; Morteza Karimipoor; Reza Mahdian; Atefeh Alipour; Saadi Hosseini; Marzieh Mohammadi; Hooman Kaghazian; Hosein Shahsavarani; Mohammad Ali Shokrgozar

6

A pre-integrated dCas9-VPR CRISPRa platform for high-level recombinant protein production in CHO cells

Biochemical Engineering Journal 232 (2026)

Yuan Tian; Yanan Zhou; Wan-Shun Hu; Jiao Xu; Qian Ye; Wen‐Song Tan

7

CHO endogenous weak promoters facilitating the development of high-yield cell lines

Journal of Biotechnology 416 (2026)

Yuan Tian; Yanan Zhou; Zhi-Ying Xiao; Liang Zhao; Qian Ye; Wen-Song Tan

8

A high-throughput co-culture CRISPR array for rapid fitness hypothesis testing and growth engineering in CHO cells

iScience 29(9) (2026)

Jannis Marzluf; Lea Huckfeldt; Dominik Haidas; Christoph Zehe; Ann‐Cathrin Leroux