QT Dispersion and T Wave Peak–to–end Interval Dispersion in Children with Kawasaki Disease

Hamid  Amoozgar; Maryam  Ahmadipour; Anis  Amirhakimi

International Cardiovascular Research Journal

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

Current Issue All Issues In Press Accepted Manuscripts Search

Journal Information Boards & Committees Indexing and Listing Sources Journal Metrics Publication Ethics and Publication Malpractice Statement Reviewer and AE Registration Form Support Contact Us

APC

Authors Guide Submit Manuscript

QT Dispersion and T Wave Peak–to–end Interval Dispersion in Children with Kawasaki Disease

Author(s):

Hamid Amoozgar¹,

Maryam Ahmadipour^2,*,

Anis Amirhakimi²

1Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

2Division of Pediatric Cardiology, Department of Pediatric, Shiraz University of Medical Sciences, Shiraz, Iran

International Cardiovascular Research Journal:Vol. 7, issue 3; e12427

Published online:Sep 30, 2013

Article type:Research Article

Received:May 03, 2017

Accepted:Jul 13, 2013

How to Cite:Amoozgar H, Ahmadipour M, Amirhakimi A. QT Dispersion and T Wave Peak–to–end Interval Dispersion in Children with Kawasaki Disease. Int Cardiovasc Res J. 2017;7(3):e12427. doi:

Abstract

Background: The main complication of Kawasaki disease is the Coronary Artery (CA) involvement and long term follow up of patients depends on the severity of coronary arterial aneurysms, ischemia, and thrombosis. Early diagnosis of these complications can lead to a more desirable outcome for patients. Myocardial ischemia can prolong QT dispersion and increase the risk of cardiac arrhythmias as well as sudden cardiac arrests. Also, T wave peak–to–end (Tp-Te) interval dispersion, which provides a valuable index of transmural dispersion of repolarization, can trigger the arrhythmia.

Materials and Methods: We evaluated the non-corrected QT interval dispersion (QTD) and the corrected QT (QTc) dispersion and measured Tp–Te interval dispersion in 49 Iranian children (28 males and 21 females) with the diagnosis of Kawasaki disease (KD) in the acute phase and 49 age-matched controls in a prospective study from 2009 to 2012. Student’s t-test and Pearson correlation were used to analyze the data. All the statistical analyses were performed through the SPSS 16. Besides, P<0.05 was considered as statistically significant.

Results: Patients with KD had significantly longer QTc dispersion (0.099±0.055 s versus. 0.040±0.018 s; P<0.001), non-corrected QT dispersion (0.075±0.046 versus 0.042±0.019; P<0.001), and Tp-Te dispersion (0.047±0.054 versus 0.022±0.011; P=0.015). The patients with elevation in white blood cell count (above 15000) had a statistically significant increased in QTD (P=0.011). No significant correlation was found between coronary involvement and repolarization indexes.

Conclusions: In conclusion, the QT interval (corrected or non-corrected) and the Tp-Te dispersion significantly increased in the patients with KD which shows repolarization changes during the acute phase of KD. However, there is no correlation between the QT interval and the coronary involvement.

Keywords

Kawasaki

Dispersion

Electrocardiogram

Fulltext

The full text is available in PDF.

References

1.
The references are available in PDF.

Kawasaki Disease in 159 Iranian Children

Mohammad Hassan Moradinejad,

Abdolrazagh Kiani

Moradinejad MH, Kiani A. Kawasaki Disease in 159 Iranian Children. J Compr Ped. 2007;1(1):. doi:

30

Jun

2007

Clinical symptoms and laboratory findings of Kawasaki disease in children

P Ayazi,

Gh. Mohammadzadeh,

F. Arian far

Ayazi P, Mohammadzadeh G, Arian far F. Clinical symptoms and laboratory findings of Kawasaki disease in children. J Inflamm Dis. 2024;11(1):e155279. doi:

31

Dec

2007

Kawasaki Disease (KD) in Iran: A Report of 85 Cases

Ahmad Siadati,

Farah Sabouni

Siadati A, Sabouni F. Kawasaki Disease (KD) in Iran: A Report of 85 Cases. J Compr Ped. 2007;1(2):. doi:

27

Feb

2014

Clinical Characteristics and Outcomes of Iranian Patients With Kawasaki Disease

Iraj Sedighi,

Mansoureh Biglari,

Mehrnaz Olfat,

Habibollah Yadolahi,

Asadolah Tanasan,

Saadat Torabian

Sedighi I, Biglari M, Olfat M, Yadolahi H, Tanasan A, et al. Clinical Characteristics and Outcomes of Iranian Patients With Kawasaki Disease. J Compr Ped. 2014;5(1):e13971. doi: https://doi.org/10.17795/compreped-13971

31

Dec

2013

The Relationship between QT Interval Dispersion and End-Stage Liver Disease Score in the Patients Undergoing Orthotopic Liver Transplantation

Moghgan Zahmatkeshan,

Ebrahim Fallahzadeh,

Seyedeh Sadat Najib,

Hamid Amoozgar,

Seyed Ali Malekhosseini,

Saman Nikeghbalian

Zahmatkeshan M, Fallahzadeh E, Sadat Najib S, Amoozgar H, Malekhosseini SA, et al. The Relationship between QT Interval Dispersion and End-Stage Liver Disease Score in the Patients Undergoing Orthotopic Liver Transplantation. Int Cardiovasc Res J. 2017;7(4):e12369. doi:

Import into EndNote Import into BibTex

Share on

Comments

Number of Comments:0

Cited by

Scopus by DOI: 0
Last Update: 4 days ago
Scopus by Title: 15
Last Update: 4 days ago
Scopus by Title (Ref): 0
Last Update: 4 days ago
CrossRef: 0
Last Update: 18 hours ago

Metrics

Ordering Reprints

Articles are published under the Creative Commons license stated on each article. No permission or royalty fee is required for uses permitted by that license. CCC handles optional bulk and customized reprint orders. Any quotation covers production and delivery services only, not copyright permission. > Request Reprints from CCC

Search Relations

Author(s):

Hamid Amoozgar:[PubMed][Scholar]
Maryam Ahmadipour:[PubMed][Scholar]
Anis Amirhakimi:[PubMed][Scholar]

The Official Annually Journal of Cardiovascular Research Center, Shiraz University of Medical Sciences

Outlines

QT Dispersion and T Wave Peak–to–end Interval Dispersion in Children with Kawasaki Disease

Abstract

Fulltext

References

Similar Articles

Kawasaki Disease in 159 Iranian Children

Clinical symptoms and laboratory findings of Kawasaki disease in children

Kawasaki Disease (KD) in Iran: A Report of 85 Cases

Clinical Characteristics and Outcomes of Iranian Patients With Kawasaki Disease

The Relationship between QT Interval Dispersion and End-Stage Liver Disease Score in the Patients Undergoing Orthotopic Liver Transplantation

Last Update: 4 days ago

Last Update: 4 days ago

Last Update: 4 days ago

Last Update: 18 hours ago