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Journal of Clinical Research in Paramedical Sciences
The Official Journal of Paramedical School, KUMS
e-ISSN 2345-3338
p-ISSN 2322-1593
Image Credit:J Clin Res Paramed Sci
Outline
The frequency study of anti HLA antibodies of platelet in patients who received blood component in Imam Reza and Taleghani hospitals in Kermanshah
Authors
Daryoush Pourmand1, Soraya Bilvaye1,*, Bahram Ebrahimi2, Mozafar Aznab3, Sahar Afzali1, Shahin Karimi4, Seyed Siamak Peyambari3
1Department of Medical Laboratory Sciences, Paramedicine Faculty, Kermanshah University of Medical Sciences, Kermanshah, Iran
2Blood Transfusion Organization Kermanshah, Kermanshah, Iran
3Department of Oncology, Taleghani Hospital, Kermanshah, Iran
4Department of Oncology, Imam Reza Hospital, Kermanshah, Iran
*Corresponding Author: Corresponding author: Soraya Bilvaye, Department of Medical Laboratory Sciences, Paramedicine Faculty, Kermanshah University of Medical Sciences, Kermanshah, Iran, E-mail: Email: sbilvayeh1371@gmail.com
Published online:May 17, 2015
Article type:Brief Report
Received:Nov 12, 2014
Accepted:Mar 25, 2015
How to Cite:Pourmand D, Bilvaye S, Ebrahimi B, Aznab M, Afzali S, et al. The frequency study of anti HLA antibodies of platelet in patients who received blood component in Imam Reza and Taleghani hospitals in Kermanshah. J Clin Res Paramed Sci. 2015;4(1):e81959. doi:
Abstract
There are alloantibody in the patient with hematologic disorders like acute leukemia and multiple blood transfusion. These alloantibodies are IgM and IgG antibodies against
alloantigens of platelets like HLA antigen.
Platelets resistant was detected in 2-30% of patients with blood transfusion and in 50% patients case a unsuitable respond to platelet transfusion in patients.
In this descriptive analytic Study anti platlet antibodes were detected by lymphocytotoxicity method in 18 patients that received blood and blood components in Imam Reza and Taleghani hospitals.
Anti HLA antibodies detected in 9 of 18 sample of patients with blood disorder and malignance. The mean of old in samples was 24.5 years.
Anti HLA antibodies were detected in 50% of study patients. There were not significant related in anti HLA antibodies and FFP, platelet rates and times of hospitalization. But between ratty and times of pack cell transfusion and anti HLA antibodies a significant related was seen.
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Copyright
© 2015, Journal of Clinical Research in Paramedical Sciences. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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