Journal of Inflammatory Diseases
The Official Journal of Qazvin University of Medical Sciences
The efficiency of Albendazole and Mebendazole in the treatment of ascariasis and trichuriasis
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Abstract
Abstract Background: High prevalence of intestinal parasites in Iran, Specially Hamedan, demands a suitable drug of choice. Objective: To compare the efficiency of albendazole and mebndazole on ascarisis and trichuriasis. Methods: In a triple – blind clinical study, 162 students of Cheshin and Abarru villages who were infected by ascaris lumbricoides and trichuris trichiura were randomly divided into 2 groups in which albendazole and mebendazole were prescribed for them .The collected data was analyzed by chi2, fisher and t-student tests. Findings: The effectiveness of albendazole and mebendazole on ascariasis and trichuriasis were 96.3, 83.2 and 98.7, 100 respectively .No side- effects of albendazole and mebendazole were observed in 89% and 90% of the patients respectively. Conclusion: There is no superiority in prescribing albendazole in comparision to 500 mg single does of mebendazole for treatment of infections of intestinal nematodes.
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© 2024, Journal of Inflammatory Diseases. This open-access article is available under the Creative Commons Attribution-NonCommercial 4.0 (CC BY-NC 4.0) International License (https://creativecommons.org/licenses/by-nc/4.0/), which allows for the copying and redistribution of the material only for noncommercial purposes, provided that the original work is properly cited.
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