Assessing roll-over test in early diagnosis of preeclampsia

¯Abstract Background: Prediction of preeclampsia can reduce the mortality and morbidity and one of the early predictive methods of this disease is roll-over test. Objective: To determine the positive predictive value of roll-over test in diagnosis of preeclampsia. Methods: A sample of 140 healthy women with risk factors of preeclampsia at 28-32 weeks of gestation were assessed prospectively by roll over test. Selected samples followed to 24 hours after delivery for signs of preeclampsia. Findings: The results showed that in 71.4% of patients with positive roll-over test developed preeclampsia, whereas in 9.8% of patients with negative roll-over test developed preeclampsia. The results showed that the sensitivity of roll-over test is 64% and the specificity is 92%. The positive predictive value in this study was 71% and the negative predictive value was 90%. Also, the results showed that there is no significant relation between BP, Rh factor and weight with preeclampsia, but there is significant relation between blood group and pre-eclampsia (P=0.003). Conclusion: This study showed that roll-over test is a practical method for prediction of preeclampsia in high risk women.